Risultati della ricerca - Sandra E. Dunn

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  1. 1
    Concise Review: Bullseye: Targeting Cancer Stem Cells to Improve the Treatment of Gliomas by Repurposing Disulfiram

    Concise Review: Bullseye: Targeting Cancer Stem Cells to Improve the Treatment of Gliomas by Repurposing Disulfiram di Joanna Triscott, Mary Rose Pambid, Sandra E. Dunn

    Pubblicazione 2015
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  2. 2
    Small interfering RNA library screen identified polo-like kinase-1 (PLK1) as a potential therapeutic target for breast cancer that uniquely eliminates tumor-initiating cells

    Small interfering RNA library screen identified polo-like kinase-1 (PLK1) as a potential therapeutic target for breast cancer that uniquely eliminates tumor-initiating cells di Kaiji Hu, Jennifer Law, Abbas Fotovati, Sandra E. Dunn

    Pubblicazione 2012
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  3. 3
    Medulloblastoma stem cells: where development and cancer cross pathways

    Medulloblastoma stem cells: where development and cancer cross pathways di Branavan Manoranjan, Chitra Venugopal, Nicole McFarlane, Bradley W. Doble, Sandra E. Dunn, Katrin Scheinemann, Sheila K. Singh

    Pubblicazione 2012
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  4. 4
    MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition

    MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition di Arezoo Astanehe, Melanie Finkbeiner, Martin Krzywinski, Abbas Fotovati, Jaspreet Dhillon, Isabelle M. Berquin, Gordon B. Mills, Marco A. Marra, Sandra E. Dunn

    Pubblicazione 2012
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  5. 5
    Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress

    Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress di Aditi U. Gurkar, Kiki Chu, Lakshmi Raj, Richard Bouley, Seung‐Hwan Lee, Young‐Bum Kim, Sandra E. Dunn, Anna Mandinova, Sam W. Lee

    Pubblicazione 2013
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  6. 6
    Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes

    Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes di Golareh Habibi, Samuel Leung, Jennifer Law, Karen A. Gelmon, Hamid Masoudi, Dmitry Turbin, Michaël Pollak, Torsten O. Nielsen, David G. Huntsman, Sandra E. Dunn

    Pubblicazione 2008
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  7. 7
    Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer

    Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer di Nattapon Panupinthu, Shoujia Yu, D Zhang, F Zhang, Mihai Gagea, Yiling Lu, Jennifer R. Grandis, Sandra E. Dunn, H Y Lee, Gordon B. Mills

    Pubblicazione 2013
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  8. 8
    The transcriptional induction of PIK3CA in tumor cells is dependent on the oncoprotein Y-box binding protein-1

    The transcriptional induction of PIK3CA in tumor cells is dependent on the oncoprotein Y-box binding protein-1 di Arezoo Astanehe, Melanie Finkbeiner, Payman Hojabrpour, Karen To, Abbas Fotovati, Ashleen Shadeo, Anna L. Stratford, Wan L. Lam, Isabelle M. Berquin, Vincent Duronio, Sandra E. Dunn

    Pubblicazione 2009
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  9. 9
    Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells

    Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells di Anna L. Stratford, Christopher J. Fry, Curtis Desilets, Alastair Davies, Yong‐Yeon Cho, Yvonne Li, Zigang Dong, Isabelle M. Berquin, Philippe P. Roux, Sandra E. Dunn

    Pubblicazione 2008
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  10. 10
    Targeting YB-1 in HER-2 Overexpressing Breast Cancer Cells Induces Apoptosis via the mTOR/STAT3 Pathway and Suppresses Tumor Growth in Mice

    Targeting YB-1 in HER-2 Overexpressing Breast Cancer Cells Induces Apoptosis via the mTOR/STAT3 Pathway and Suppresses Tumor Growth in Mice di Cathy Lee, Jaspreet Dhillon, Michelle Y.C. Wang, Yuanyuan Gao, Kaiji Hu, Eugene Park, Arezoo Astanehe, Mien‐Chie Hung, Peter Eirew, Connie J. Eaves, Sandra E. Dunn

    Pubblicazione 2008
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  11. 11
    Nuclear detection of Y-boxprotein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer

    Nuclear detection of Y-boxprotein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer di Edgar Dahl, Abdelaziz En‐Nia, Frank Wiesmann, Renate Krings, Sonja Djudjaj, Elisabeth Breuer, Thomas J. Fuchs, Peter J. Wild, Arndt Hartmann, Sandra E. Dunn, Peter R. Mertens

    Pubblicazione 2009
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  12. 12
    YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification

    YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification di Alastair Davies, Irene Barrett, Mary Rose Pambid, Kaiji Hu, Anna L. Stratford, Spencer A. Freeman, Isabelle M. Berquin, Steven Pelech, P. Hieter, Christopher A. Maxwell, Sandra E. Dunn

    Pubblicazione 2011
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  13. 13
    YB-1 Expression and Phosphorylation Regulate Tumorigenicity and Invasiveness in Melanoma by Influencing EMT

    YB-1 Expression and Phosphorylation Regulate Tumorigenicity and Invasiveness in Melanoma by Influencing EMT di Corinna Kosnopfel, Tobias Sinnberg, Birgit Sauer, Christian Busch, Heike Niessner, Anja Schmitt, Stephan Forchhammer, Cornelia Grimmel, Peter R. Mertens, Stephan Hailfinger, Sandra E. Dunn, Claus Garbe, Birgit Schittek

    Pubblicazione 2018
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  14. 14
    Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours

    Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours di Jill E. Kucab, Cathy Lee, Ching‐Shih Chen, Jiuxiang Zhu, C. Blake Gilks, Maggie C.U. Cheang, David G. Huntsman, Erika Yorida, Joanne T. Emerman, Michaël Pollak, Sandra E. Dunn

    Pubblicazione 2005
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  15. 15
    Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)

    Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) di Kristen M. Reipas, Jennifer Law, Nicole Couto, Sumaiya Islam, Yvonne Li, Huifang Li, Artem Cherkasov, Karen Jung, Amarpal S. Cheema, Steven J.M. Jones, John A. Hassell, Sandra E. Dunn

    Pubblicazione 2013
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  16. 16
    Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide

    Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide di Joanna Triscott, Cathy Lee, Kaiji Hu, Abbas Fotovati, Rachel Berns, Mary Rose Pambid, Margaret Luk, Richard E. Kast, Esther Kong, Eric Toyota, Stephen Yip, Brian Toyota, Sandra E. Dunn

    Pubblicazione 2012
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  17. 17
    Disruption of the Y-Box Binding Protein-1 Results in Suppression of the Epidermal Growth Factor Receptor and HER-2

    Disruption of the Y-Box Binding Protein-1 Results in Suppression of the Epidermal Growth Factor Receptor and HER-2 di Joyce C. Wu, Cathy Lee, Daniel Yokom, Helen Jiang, Maggie C.U. Cheang, Erika Yorida, Dmitry Turbin, Isabelle M. Berquin, Peter R. Mertens, Thomas Iftner, C. Blake Gilks, Sandra E. Dunn

    Pubblicazione 2006
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  18. 18
    Targeting p90 Ribosomal S6 Kinase Eliminates Tumor-Initiating Cells by Inactivating Y-Box Binding Protein-1 in Triple-Negative Breast Cancers

    Targeting p90 Ribosomal S6 Kinase Eliminates Tumor-Initiating Cells by Inactivating Y-Box Binding Protein-1 in Triple-Negative Breast Cancers di Anna L. Stratford, Kristen M. Reipas, Kaiji Hu, Abbas Fotovati, Rachel Brough, Jessica Frankum, Mandeep Takhar, Peter H. Watson, Alan Ashworth, Christopher J. Lord, Annette Lasham, Cristin G. Print, Sandra E. Dunn

    Pubblicazione 2012
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  19. 19
    Preferential Dependence of Breast Cancer Cells versus Normal Cells on Integrin-Linked Kinase for Protein Kinase B/Akt Activation and Cell Survival

    Preferential Dependence of Breast Cancer Cells versus Normal Cells on Integrin-Linked Kinase for Protein Kinase B/Akt Activation and Cell Survival di Armelle A. Troussard, Paul C. McDonald, Elizabeth D. Wederell, Nasrin M. Mawji, Nolan R. Filipenko, Karen A. Gelmon, Jill E. Kucab, Sandra E. Dunn, Joanne T. Emerman, Marcel B. Bally, Shoukat Dedhar

    Pubblicazione 2006
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  20. 20
    Polo-Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice

    Polo-Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice di Cathy Lee, Abbas Fotovati, Joanna Triscott, James Chen, Chitra Venugopal, Ash Singhal, Christopher Dunham, J. M. Munro Kerr, Maïté Verreault, Stephen Yip, Hiroaki Wakimoto, Chris Jones, Aarthi Jayanthan, Aru Narendran, Sheila K. Singh, Sandra E. Dunn

    Pubblicazione 2012
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