Search Results - Sandra Duffy

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  1. 1
    Identification of inhibitors of Plasmodium falciparum gametocyte development

    Identification of inhibitors of Plasmodium falciparum gametocyte development by Sandra Duffy, Vicky M. Avery

    Published 2013
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  2. 2
    Development and Optimization of a Novel 384-Well Anti-Malarial Imaging Assay Validated for High-Throughput Screening

    Development and Optimization of a Novel 384-Well Anti-Malarial Imaging Assay Validated for High-Throughput Screening by Sandra Duffy, Vicky M. Avery

    Published 2012
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  3. 3
    Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay

    Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay by Leonardo Lucantoni, Sandra Duffy, Sophie Adjalley, David A. Fidock, Vicky M. Avery

    Published 2013
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  4. 4
    Antimalarial Activity of Azafluorenone Alkaloids from the Australian Tree <i>Mitrephora diversifolia</i>

    Antimalarial Activity of Azafluorenone Alkaloids from the Australian Tree <i>Mitrephora diversifolia</i> by Daniela Mueller, Rohan A. Davis, Sandra Duffy, Vicky M. Avery, David Camp, Ronald J. Quinn

    Published 2009
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  5. 5
    Antimalarial Bromotyrosine Derivatives from the Australian Marine Sponge <i>Hyattella</i> sp.

    Antimalarial Bromotyrosine Derivatives from the Australian Marine Sponge <i>Hyattella</i> sp. by Xinzhou Yang, Rohan A. Davis, Malcolm S. Buchanan, Sandra Duffy, Vicky M. Avery, David Camp, Ronald J. Quinn

    Published 2010
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  6. 6
    Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery

    Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery by Sandra Duffy, Melissa L. Sykes, Amy J. Jones, Todd Shelper, Moana Simpson, Rebecca Lang, Sally‐Ann Poulsen, Brad E. Sleebs, Vicky M. Avery

    Published 2017
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  7. 7
    Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum

    Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum by Vicky M. Avery, Sridevi Bashyam, Jeremy N. Burrows, Sandra Duffy, George Papadatos, Shyni Puthukkuti, Yuvaraj Sambandan, Shivendra V. Singh, Thomas Spangenberg, David Waterson, Paul Willis

    Published 2014
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  8. 8
    Antimalarial Activity of Pyrroloiminoquinones from the Australian Marine Sponge <i>Zyzzya</i> sp.

    Antimalarial Activity of Pyrroloiminoquinones from the Australian Marine Sponge <i>Zyzzya</i> sp. by Rohan A. Davis, Malcolm S. Buchanan, Sandra Duffy, Vicky M. Avery, Susan A. Charman, William N. Charman, Karen L. White, David M. Shackleford, Michael D. Edstein, Katherine T. Andrews, David Camp, Ronald J. Quinn

    Published 2012
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  9. 9
    One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites

    One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites by Daniela Diedrich, Katharina Stenzel, Eva Hesping, Yevgeniya Antonova‐Koch, Tamirat Gebru, Sandra Duffy, Gillian M. Fisher, Andrea Schöler, Stephan Meister, Thomas Kurz, Vicky M. Avery, Elizabeth A. Winzeler, Jana Held, Katherine T. Andrews, Finn K. Hansen

    Published 2018
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  10. 10
    Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages

    Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages by Finn K. Hansen, Subathdrage D.M. Sumanadasa, Katharina Stenzel, Sandra Duffy, Stephan Meister, Linda Marek, Rebekka Schmetter, Krystina Kuna, Alexandra Hamacher, Benjamin Mordmüller, Matthias U. Kassack, Elizabeth A. Winzeler, Vicky M. Avery, Katherine T. Andrews, Thomas Kurz

    Published 2014
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  11. 11
    Repositioning: the fast track to new anti-malarial medicines?

    Repositioning: the fast track to new anti-malarial medicines? by Julie Lotharius, Francisco Javier Gamo‐Benito, Íñigo Angulo‐Barturen, Julie Clark, Michele Connelly, Santiago Ferrer, Tanya Parkinson, Pavithra Viswanath, Balachandra Bandodkar, Nikhil Rautela, Sowmya Bharath, Sandra Duffy, Vicky M. Avery, Jörg J. Möhrle, R. Kiplin Guy, Timothy N. C. Wells

    Published 2014
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  12. 12
    Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules

    Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules by Katharine R. Trenholme, Linda Marek, Sandra Duffy, Gabriele Pradel, Gillian M. Fisher, Finn K. Hansen, Tina S. Skinner‐Adams, Alice Butterworth, Che Julius Ngwa, Jonas Moecking, C.D. Goodman, Geoffrey I. McFadden, Subathdrage D.M. Sumanadasa, David P. Fairlie, Vicky M. Avery, Thomas Kurz, Katherine T. Andrews

    Published 2014
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  13. 13
    Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

    Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity by Paul R. Gilson, Cyrus Tan, Kate E. Jarman, Kym N. Lowes, Joan Curtis, William Nguyen, Adrian E. Di Rago, Hayley E. Bullen, Boris Prinz, Sandra Duffy, Jonathan B. Baell, Craig A. Hutton, Helene Jousset Subroux, Brendan S. Crabb, Vicky M. Avery, Alan F. Cowman, Brad E. Sleebs

    Published 2017
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  14. 14
    Histone Methyltransferase Inhibitors Are Orally Bioavailable, Fast-Acting Molecules with Activity against Different Species Causing Malaria in Humans

    Histone Methyltransferase Inhibitors Are Orally Bioavailable, Fast-Acting Molecules with Activity against Different Species Causing Malaria in Humans by Nicholas A. Malmquist, Sandeep Sundriyal, Joachim Caron, Patty Chen, Benoît Witkowski, Didier Ménard, Rossarin Suwanarusk, Laurent Rénia, François Nosten, Marı́a Belén Jiménez-Dı́az, Íñigo Angulo‐Barturen, María Santos Martínez, Santiago Ferrer, Laura M. Sanz, Francisco‐Javier Gamo, Sergio Wittlin, Sandra Duffy, Vicky M. Avery, Andrea Ruecker, Michael J. Delves, Robert E. Sinden, Matthew J. Fuchter, Artur Scherf

    Published 2014
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  15. 15
    Target Validation and Identification of Novel Boronate Inhibitors of the <i>Plasmodium falciparum</i> Proteasome

    Target Validation and Identification of Novel Boronate Inhibitors of the <i>Plasmodium falciparum</i> Proteasome by Stanley C. Xie, David L. Gillett, Natalie J. Spillman, Christopher Tsu, Madeline R. Luth, Sabine Ottilie, Sandra Duffy, Alexandra E. Gould, Paul Hales, Benjamin A. Seager, Carlie L. Charron, Frank J. Bruzzese, Xiaofeng Yang, Xiansi Zhao, Shih‐Chung Huang, Craig A. Hutton, Jeremy N. Burrows, Elizabeth A. Winzeler, Vicky M. Avery, Lawrence R. Dick, Leann Tilley

    Published 2018
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  16. 16
    Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

    Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy by Beatriz Baragaña, Neil R. Norcross, Caroline Wilson, Achim Porzelle, Irene Hallyburton, Raffaella Grimaldi, Maria Osuna‐Cabello, Suzanne Norval, Jennifer Riley, Laste Stojanovski, Frederick R. C. Simeons, Paul G. Wyatt, Michael J. Delves, Stephan Meister, Sandra Duffy, Vicky M. Avery, Elizabeth A. Winzeler, Robert E. Sinden, Sergio Wittlin, Julie A. Frearson, David W. Gray, Alan H. Fairlamb, David Waterson, Simon F. Campbell, Paul Willis, Kevin D. Read, Ian H. Gilbert

    Published 2016
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  17. 17
    Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity

    Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity by Manu Vanaerschot, Leonardo Lucantoni, Tao Li, Jill M. Combrinck, Andrea Ruecker, T. R. Santha Kumar, Kelly Rubiano, Pedro Eduardo Ferreira, Giulia Siciliano, Sonia Gulati, Philipp P. Henrich, Caroline L. Ng, James M. Murithi, Victoria Corey, Sandra Duffy, Ori J. Lieberman, María Isabel Veiga, Robert E. Sinden, Pietro Alano, Michael J. Delves, Kim Lee Sim, Elizabeth A. Winzeler, Timothy J. Egan, Stephen L. Hoffman, Vicky M. Avery, David A. Fidock

    Published 2017
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  18. 18
    Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as <i>Plasmodium</i> Cytoplasmic Prolyl-tRNA Synthetase Inhibitors

    Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as <i>Plasmodium</i> Cytoplasmic Prolyl-tRNA Synthetase Inhibitors by Masanori Okaniwa, Akira Shibata, Atsuko Ochida, Yuichiro Akao, Karen L. White, David M. Shackleford, Sandra Duffy, Leonardo Lucantoni, Sumanta Dey, Josefine Striepen, Tomas Yeo, Sachel Mok, Anna Caroline Campos Aguiar, Angelika Sturm, Benigno Crespo, Laura M. Sanz, Alisje Churchyard, Jake Baum, Dhélio B. Pereira, Rafael V. C. Guido, Koen J. Dechering, Sergio Wittlin, Anne‐Catrin Uhlemann, David A. Fidock, Jacquin C. Niles, Vicky M. Avery, Susan A. Charman, Benoı̂t Laleu

    Published 2021
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  19. 19
    Chemical genetics of Plasmodium falciparum

    Chemical genetics of Plasmodium falciparum by W. Armand Guiguemde, Anang A. Shelat, David C. Bouck, Sandra Duffy, Gregory J. Crowther, Paul H. Davis, David C. Smithson, Michele Connelly, Julie Clark, Fangyi Zhu, Marı́a Belén Jiménez-Dı́az, María Santos Martínez, Emily B. Wilson, Abhai K. Tripathi, Jiří Gut, Elizabeth R. Sharlow, Ian Bathurst, Farah El Mazouni, Joseph Fowble, Isaac Forquer, Paula L. McGinley, Steve Castro, Íñigo Angulo‐Barturen, Santiago Ferrer, Philip J. Rosenthal, Joseph L. DeRisi, David J. Sullivan, John S. Lazo, David S. Roos, Michael K. Riscoe, Margaret A. Phillips, Pradipsinh K. Rathod, Wesley C. Van Voorhis, Vicky M. Avery, R. Kiplin Guy

    Published 2010
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  20. 20
    Quinolone-3-Diarylethers: A New Class of Antimalarial Drug

    Quinolone-3-Diarylethers: A New Class of Antimalarial Drug by Aaron Nilsen, Alexis N. LaCrue, Karen L. White, Isaac Forquer, R. Matthew Cross, Jutta Marfurt, Michael W. Mather, Michael J. Delves, David M. Shackleford, Fabián E. Saénz, Joanne M. Morrisey, Jessica Steuten, Tina Mutka, Yuexin Li, Grennady Wirjanata, Eileen Ryan, Sandra Duffy, Jane X. Kelly, Boni F. Sebayang, Anne‐Marie Zeeman, Rintis Noviyanti, Robert E. Sinden, Clemens H. M. Kocken, Ric N. Price, Vicky M. Avery, Íñigo Angulo‐Barturen, Marı́a Belén Jiménez-Dı́az, Santiago Ferrer, Esperanza Herreros, Laura M. Sanz, Francisco‐Javier Gamo, Ian Bathurst, Jeremy N. Burrows, Peter K. S. Siegl, R. Kiplin Guy, Rolf W. Winter, Akhil B. Vaidya, Susan A. Charman, Dennis E. Kyle, Roman Manetsch, Michael K. Riscoe

    Published 2013
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