Resultats de la cerca - Samuel Lara‐Reyna

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  1. 1
    Tumour necrosis factor signalling in health and disease

    Tumour necrosis factor signalling in health and disease per Jonathan Holbrook, Samuel Lara‐Reyna, Heledd Jarosz-Griffiths, Michael McDermott

    Publicat 2019
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  2. 2
    TNF receptor signalling in autoinflammatory diseases

    TNF receptor signalling in autoinflammatory diseases per Heledd Jarosz-Griffiths, Jonathan Holbrook, Samuel Lara‐Reyna, Michael McDermott

    Publicat 2019
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  3. 3
    Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations

    Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations per Samuel Lara‐Reyna, Jonathan Holbrook, Heledd Jarosz-Griffiths, D. Peckham, Michael McDermott

    Publicat 2020
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  4. 4
    Inflammasome activation: from molecular mechanisms to autoinflammation

    Inflammasome activation: from molecular mechanisms to autoinflammation per Samuel Lara‐Reyna, Emily A. Caseley, Joanne Topping, François Rodrigues, Jorge L. Jimenez-Macias, Sean E. Lawler, Michael McDermott

    Publicat 2022
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  5. 5
    Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation

    Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation per Samuel Lara‐Reyna, Thomas Scambler, Jonathan Holbrook, Chi Huey Wong, Heledd Jarosz-Griffiths, Fabio Martinon, Sinisa Savic, D. Peckham, Michael McDermott

    Publicat 2019
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  6. 6
    Neurodegenerative Disease and the NLRP3 Inflammasome

    Neurodegenerative Disease and the NLRP3 Inflammasome per Jonathan Holbrook, Heledd Jarosz-Griffiths, Emily A. Caseley, Samuel Lara‐Reyna, James A. Poulter, Caroline H. Williams‐Gray, D. Peckham, Michael McDermott

    Publicat 2021
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  7. 7
    ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis

    ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis per Thomas Scambler, Heledd Jarosz-Griffiths, Samuel Lara‐Reyna, Shelly Pathak, Chi Huey Wong, Jonathan Holbrook, Fabio Martinon, Sinisa Savic, D. Peckham, Michael McDermott

    Publicat 2019
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  8. 8
    Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen

    Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen per Chinaemerem U. Onyishi, Guillaume E. Desanti, Alex L. Wilkinson, Samuel Lara‐Reyna, Eva‐Maria Frickel, György Fejér, Olivier D. Christophe, Clare Bryant, Subhankar Mukhopadhyay, Siamon Gordon, Robin C. May

    Publicat 2023
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  9. 9
    Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis

    Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis per Heledd Jarosz-Griffiths, Thomas Scambler, Chi Huey Wong, Samuel Lara‐Reyna, Jonathan Holbrook, Fabio Martinon, Sinisa Savic, Paul Whitaker, C. Etherington, Giulia Spoletini, I. Clifton, Anil Mehta, Michael McDermott, D. Peckham

    Publicat 2020
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  10. 10
    PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection

    PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection per Daniel Fisch, Moritz M. Pfleiderer, Eleni Anastasakou, Gillian M. Mackie, Fabian Wendt, Xiangyang Liu, Barbara Clough, Samuel Lara‐Reyna, Vesela Encheva, Ambrosius P. Snijders, Hironori Bando, Masahiro Yamamoto, Andrew D. Beggs, Jason Mercer, Avinash R. Shenoy, Bernd Wollscheid, Kendle M. Maslowski, Wojciech P. Galej, Eva‐Maria Frickel

    Publicat 2023
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  11. 11
    Depletion of WFS1 compromises mitochondrial function in hiPSC-derived neuronal models of Wolfram syndrome

    Depletion of WFS1 compromises mitochondrial function in hiPSC-derived neuronal models of Wolfram syndrome per Malgorzata Zatyka, Tatiana R. Rosenstock, Congxin Sun, Adina M. Palhegyi, Georgina W. Hughes, Samuel Lara‐Reyna, Dewi Astuti, Alessandro Di Maio, Axel Sciauvaud, Miriam E. Korsgen, Vesna Stanulovic, Gamze Koçak, Malgorzata Rak, Sandra Pourtoy-Brasselet, Katherine Winter, Thiago Varga, Margot Jarrige, Hélène Polvèche, Joao Correia, Eva‐Maria Frickel, Maarten Hoogenkamp, Douglas G. Ward, Laëtitia Aubry, Timothy Barrett, Sovan Sarkar

    Publicat 2023
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  12. 12
    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency per Congxin Sun, Elena Seranova, Malkiel A. Cohen, Miruna Chipara, Jennie Roberts, Dewi Astuti, Adina M. Palhegyi, Animesh Acharjee, Lucia Sedlackova, Tetsushi Kataura, Elsje G. Otten, Prashanta Kumar Panda, Samuel Lara‐Reyna, Miriam E. Korsgen, Kevin Kauffman, Alejandro Huerta Uribe, Malgorzata Zatyka, Luiz Silva, Jorge Torresi, Shupei Zhang, Georgina W. Hughes, Carl Ward, Erich R. Kuechler, David Cartwright, Sergey Trushin, Eugenia Trushina, Gaurav Sahay, Yosef Buganim, Gareth G. Lavery, Joerg Gsponer, Daniel G. Anderson, Eva‐Maria Frickel, Tatiana R. Rosenstock, Timothy Barrett, Oliver D.K. Maddocks, Daniel A. Tennant, Haoyi Wang, Rudolf Jaenisch, Viktor I. Korolchuk, Sovan Sarkar

    Publicat 2023
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