检索结果 - Sampath, Deepa

Context-dependent actions of miR-106b in CLL 由 Sampath, Deepa, Plunkett, William

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ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replications forks and contribute to drug resistance 由 Ewald, Brett, Sampath, Deepa, Plunkett, William

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CBMT-22. REVERSING THE WARBURG EFFECT BY TARGETING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT), THE RATE-LIMITING ENZYME OF NAD+ SALVAGE PATHWAY INCREASES, CHEMOSENSITIVITY TO T... 由 Sharma, Pratibha, Senapedis, William, Sampath, Deepa, Puduvalli, Vinay

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Fludarabine increases oxaliplatin cytotoxicity in normal and chronic lymphocytic leukemia lymphocytes by suppressing interstrand DNA crosslink removal 由 Moufarij, Mazin A., Sampath, Deepa, Keating, Michael J., Plunkett, William

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Killing of chronic lymphocytic leukemia by the combination of fludarabine and oxaliplatin is dependent on the activity of XPF endonuclease 由 Zecevic, Alma, Sampath, Deepa, Ewald, Brett, Chen, Rong, Wierda, William, Plunkett, William

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Explaining Gene Expression Using Twenty-One MicroRNAs 由 Asiaee, Amir, Abrams, Zachary B., Nakayiza, Samantha, Sampath, Deepa, Coombes, Kevin R.

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EXTH-54. ENHANCED SENSITIVITY OF HUMAN GLIOMA CELLS FOR TEMOZOLOMIDE (TMZ) BY COMBINING THERAPY WITH HEAT SHOCK PROTEIN 90 由 Sharma, Pratibha, Mahadevan, Lakshmi Shree K, Argall, Aaron, Xu, Jihong, Sampath, Deepa, Puduvalli, Vinay

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Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial 由 Sampath, Deepa, Cortes, Jorge, Estrov, Zeev, Du, Min, Shi, Zheng, Andreeff, Michael, Gandhi, Varsha, Plunkett, William

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Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia 由 Sampath, Deepa, Liu, Chaomei, Vasan, Karthik, Sulda, Melanie, Puduvalli, Vinay K., Wierda, William G., Keating, Michael J.

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EXTH-84. TARGETING THE SALVAGE PATHWAY OF NAD+ GENERATION IN GLIOMAS BY KPT-9274, A NOVEL DUAL INHIBITOR OF PAK4 AND NAMPT 由 Sharma, Pratibha, Kesanakurti, Divya, Wu, Pei-Jung, Xu, Jihong, Sampath, Deepa, Senapedis, William, Baloglu, Erkan, Puduvalli, Vinay K

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Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures 由 Xu, Jihong, Sampath, Deepa, Lang, Frederick F., Prabhu, Sujit, Rao, Ganesh, Fuller, Gregory N., Liu, Yuanfang, Puduvalli, Vinay K.

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Anti-tumor NAMPT inhibitor, KPT-9274, mediates gender-dependent murine anemia and nephrotoxicity by regulating SIRT3-mediated SOD deacetylation 由 Mitchell, Shaneice, Zhang, Pu, Cannon, Matthew, Beaver, Larry, Lehman, Amy, Harrington, Bonnie, Sampath, Deepa, Byrd, John C., Lapalombella, Rosa

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Role and regulation of MicroRNAs targeting BTK in acute myelogenous leukemia 由 Rizzotto, Lara, Lai, Tzung-Huei, Bottoni, Arianna, Woyach, Jennifer A, Lapalombella, Rosa, Bloomfield, Clara D, Byrd, John C, Sampath, Deepa

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HDAC inhibition induces microRNA-182 which targets Rad51 and impairs HR repair to sensitize cells to sapacitabine in acute myelogenous leukemia 由 Lai, Tsung-Huei, Ewald, Brett, Zecevic, Alma, Liu, Chaomei, Sulda, Melanie, Papaioannou, Dimitrios, Garzon, Ramiro, Blachly, J.S, Plunkett, William, Sampath, Deepa

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Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneit... 由 Sharma, Pratibha, Xu, Jihong, Williams, Katie, Easley, Michelle, Elder, J Brad, Lonser, Russell, Lang, Frederick F, Lapalombella, Rosa, Sampath, Deepa, Puduvalli, Vinay K

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Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation 由 Sampath, Deepa, Calin, George A., Puduvalli, Vinay K., Gopisetty, Gopal, Taccioli, Cristian, Liu, Chang-Gong, Ewald, Brett, Liu, Chaomei, Keating, Michael J., Plunkett, William

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EXTH-83. TARGETING DNA REPAIR AND SURVIVAL PATHWAYS THROUGH HEAT SHOCK PROTEIN INHIBITION USING AT13387 TO SENSITIZE GLIOMA TO CHEMORADIATION THERAPY 由 Wu, Jasmine P J, Canella, Alessandro, Xu, Jihong, Lai, Tzung-Huei, Welker, Alessandra M, Beattie, Christine E, Nadella, Vijay, Timmers, Cynthia, Kaur, Balveen, Jacob, Naduparambil, Sampath, Deepa, Puduvalli, Vinay K

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HSP90 inhibition depletes DNA repair proteins to sensitize acute myelogenous leukemia to nucleoside analog chemotherapeutics. 由 Lai, Tzung-Huei, Mitchell, Shaneice, Wu, Pei-Jung, Orwick, Shelley, Liu, Chaomei, Ravikrishnan, Janani, Woyach, Jennifer, Mims, Alice, Plunkett, William, Puduvalli, Vinay K, Byrd, John C, Lapalombella, Rosa, Sampath, Deepa

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XPO1 Inhibition Using Selinexor Synergizes With Chemotherapy in Acute Myeloid Leukemia (AML) by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus 由 Ranganathan, Parvathi, Kashyap, Trinayan, Yu, Xueyan, Meng, Xiaomei, Lai, Tzung-Huei, McNeil, Betina, Bhatnagar, Bhavana, Shacham, Sharon, Kauffman, Michael, Dorrance, Adrienne M., Blum, William, Sampath, Deepa, Landesman, Yosef, Garzon, Ramiro

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Phase I Clinical, Pharmacokinetic, and Pharmacodynamic Study of the Akt-Inhibitor Triciribine Phosphate Monohydrate in Patients with Advanced Hematologic Malignancies 由 Sampath, Deepa, Malik, Asifa, Plunkett, William, Nowak, Billie, Williams, Betsy, Burton, Michelle, Verstovsek, Srdan, Faderl, Stefan, Garcia-Manero, Guillermo, List, Alan F., Sebti, Said, Kantarjian, Hagop M., Ravandi, Farhad, Lancet, Jeffrey E.

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