Výsledky vyhledávání - Sampath, Deepa

Context-dependent actions of miR-106b in CLL Autor Sampath, Deepa, Plunkett, William

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ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replications forks and contribute to drug resistance Autor Ewald, Brett, Sampath, Deepa, Plunkett, William

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CBMT-22. REVERSING THE WARBURG EFFECT BY TARGETING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT), THE RATE-LIMITING ENZYME OF NAD+ SALVAGE PATHWAY INCREASES, CHEMOSENSITIVITY TO T... Autor Sharma, Pratibha, Senapedis, William, Sampath, Deepa, Puduvalli, Vinay

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Fludarabine increases oxaliplatin cytotoxicity in normal and chronic lymphocytic leukemia lymphocytes by suppressing interstrand DNA crosslink removal Autor Moufarij, Mazin A., Sampath, Deepa, Keating, Michael J., Plunkett, William

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Killing of chronic lymphocytic leukemia by the combination of fludarabine and oxaliplatin is dependent on the activity of XPF endonuclease Autor Zecevic, Alma, Sampath, Deepa, Ewald, Brett, Chen, Rong, Wierda, William, Plunkett, William

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Explaining Gene Expression Using Twenty-One MicroRNAs Autor Asiaee, Amir, Abrams, Zachary B., Nakayiza, Samantha, Sampath, Deepa, Coombes, Kevin R.

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EXTH-54. ENHANCED SENSITIVITY OF HUMAN GLIOMA CELLS FOR TEMOZOLOMIDE (TMZ) BY COMBINING THERAPY WITH HEAT SHOCK PROTEIN 90 Autor Sharma, Pratibha, Mahadevan, Lakshmi Shree K, Argall, Aaron, Xu, Jihong, Sampath, Deepa, Puduvalli, Vinay

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Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial Autor Sampath, Deepa, Cortes, Jorge, Estrov, Zeev, Du, Min, Shi, Zheng, Andreeff, Michael, Gandhi, Varsha, Plunkett, William

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Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia Autor Sampath, Deepa, Liu, Chaomei, Vasan, Karthik, Sulda, Melanie, Puduvalli, Vinay K., Wierda, William G., Keating, Michael J.

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EXTH-84. TARGETING THE SALVAGE PATHWAY OF NAD+ GENERATION IN GLIOMAS BY KPT-9274, A NOVEL DUAL INHIBITOR OF PAK4 AND NAMPT Autor Sharma, Pratibha, Kesanakurti, Divya, Wu, Pei-Jung, Xu, Jihong, Sampath, Deepa, Senapedis, William, Baloglu, Erkan, Puduvalli, Vinay K

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Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures Autor Xu, Jihong, Sampath, Deepa, Lang, Frederick F., Prabhu, Sujit, Rao, Ganesh, Fuller, Gregory N., Liu, Yuanfang, Puduvalli, Vinay K.

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Anti-tumor NAMPT inhibitor, KPT-9274, mediates gender-dependent murine anemia and nephrotoxicity by regulating SIRT3-mediated SOD deacetylation Autor Mitchell, Shaneice, Zhang, Pu, Cannon, Matthew, Beaver, Larry, Lehman, Amy, Harrington, Bonnie, Sampath, Deepa, Byrd, John C., Lapalombella, Rosa

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Role and regulation of MicroRNAs targeting BTK in acute myelogenous leukemia Autor Rizzotto, Lara, Lai, Tzung-Huei, Bottoni, Arianna, Woyach, Jennifer A, Lapalombella, Rosa, Bloomfield, Clara D, Byrd, John C, Sampath, Deepa

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HDAC inhibition induces microRNA-182 which targets Rad51 and impairs HR repair to sensitize cells to sapacitabine in acute myelogenous leukemia Autor Lai, Tsung-Huei, Ewald, Brett, Zecevic, Alma, Liu, Chaomei, Sulda, Melanie, Papaioannou, Dimitrios, Garzon, Ramiro, Blachly, J.S, Plunkett, William, Sampath, Deepa

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Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneit... Autor Sharma, Pratibha, Xu, Jihong, Williams, Katie, Easley, Michelle, Elder, J Brad, Lonser, Russell, Lang, Frederick F, Lapalombella, Rosa, Sampath, Deepa, Puduvalli, Vinay K

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Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation Autor Sampath, Deepa, Calin, George A., Puduvalli, Vinay K., Gopisetty, Gopal, Taccioli, Cristian, Liu, Chang-Gong, Ewald, Brett, Liu, Chaomei, Keating, Michael J., Plunkett, William

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EXTH-83. TARGETING DNA REPAIR AND SURVIVAL PATHWAYS THROUGH HEAT SHOCK PROTEIN INHIBITION USING AT13387 TO SENSITIZE GLIOMA TO CHEMORADIATION THERAPY Autor Wu, Jasmine P J, Canella, Alessandro, Xu, Jihong, Lai, Tzung-Huei, Welker, Alessandra M, Beattie, Christine E, Nadella, Vijay, Timmers, Cynthia, Kaur, Balveen, Jacob, Naduparambil, Sampath, Deepa, Puduvalli, Vinay K

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HSP90 inhibition depletes DNA repair proteins to sensitize acute myelogenous leukemia to nucleoside analog chemotherapeutics. Autor Lai, Tzung-Huei, Mitchell, Shaneice, Wu, Pei-Jung, Orwick, Shelley, Liu, Chaomei, Ravikrishnan, Janani, Woyach, Jennifer, Mims, Alice, Plunkett, William, Puduvalli, Vinay K, Byrd, John C, Lapalombella, Rosa, Sampath, Deepa

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XPO1 Inhibition Using Selinexor Synergizes With Chemotherapy in Acute Myeloid Leukemia (AML) by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus Autor Ranganathan, Parvathi, Kashyap, Trinayan, Yu, Xueyan, Meng, Xiaomei, Lai, Tzung-Huei, McNeil, Betina, Bhatnagar, Bhavana, Shacham, Sharon, Kauffman, Michael, Dorrance, Adrienne M., Blum, William, Sampath, Deepa, Landesman, Yosef, Garzon, Ramiro

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Phase I Clinical, Pharmacokinetic, and Pharmacodynamic Study of the Akt-Inhibitor Triciribine Phosphate Monohydrate in Patients with Advanced Hematologic Malignancies Autor Sampath, Deepa, Malik, Asifa, Plunkett, William, Nowak, Billie, Williams, Betsy, Burton, Michelle, Verstovsek, Srdan, Faderl, Stefan, Garcia-Manero, Guillermo, List, Alan F., Sebti, Said, Kantarjian, Hagop M., Ravandi, Farhad, Lancet, Jeffrey E.

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