Résultats de la recherche - Safa Al‐Sarraj
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Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages... par Andrew King, Fiona Sweeney, István Bódi, Claire Troakes, Satomi Maekawa, Safa Al‐Sarraj
Publié 2010Artigo -
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Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their... par Jorge Gomez-Deza, Youn‐Bok Lee, Claire Troakes, Matthew Nolan, Safa Al‐Sarraj, Jean‐Marc Gallo, Christopher E. Shaw
Publié 2015Artigo -
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Comparison of clinical and neuropathological diagnoses of neurodegenerative diseases in two centres from the Brains for Dementia Research (BDR) cohort par Sashika Selvackadunco, Katie Langford, Zohra Shah, Siobhan Hurley, István Bódi, Andrew King, Dag Aarsland, Claire Troakes, Safa Al‐Sarraj
Publié 2019Artigo -
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Receptor Tyrosine Kinase Genes Amplified in Glioblastoma Exhibit a Mutual Exclusivity in Variable Proportions Reflective of Individual Tumor Heterogeneity par Suzanne E. Little, Sergey Popov, Alexa Jury, Dorine A. Bax, Lawrence J. Doey, Safa Al‐Sarraj, Juliane M. Jürgensmeier, Chris Jones
Publié 2012Artigo -
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Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain par Joana Viana, Ruth Pidsley, Claire Troakes, Helen Spiers, Chloe C. Y. Wong, Safa Al‐Sarraj, Ian Craig, Leonard C. Schalkwyk, Jonathan Mill
Publié 2014Artigo -
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Concomitant neurodegenerative pathologies contribute to the transition from mild cognitive impairment to dementia par Kirsty E. McAleese, Sean J. Colloby, Alan Thomas, Safa Al‐Sarraj, Olaf Ansorge, James Neal, Federico Roncaroli, Seth Love, Paul T. Francis, Johannes Attems
Publié 2021Artigo -
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Microsatellite Instability in Pediatric High Grade Glioma Is Associated with Genomic Profile and Differential Target Gene Inactivation par Marta Viana‐Pereira, Alicia Lee, Sergey Popov, Dorine A. Bax, Safa Al‐Sarraj, Leslie Bridges, João N. Stávale, Darren Hargrave, Chris Jones, Rui Manuel Reis
Publié 2011Artigo -
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BrainNet Europe’s Code of Conduct for brain banking par Natasja Klioueva, Marleen C. Rademaker, David T. Dexter, Safa Al‐Sarraj, Danielle Seilhean, Nathalie Streichenberger, Peer Schmitz, Jeanne E. Bell, James W. Ironside, Thomas Arzberger, Inge Huitinga
Publié 2015Artigo -
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Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopatholog... par Safa Al‐Sarraj, Andrew King, M. S. Cleveland, Pierre-François Pradat, Andrea M. Corse, Jeffrey D. Rothstein, Peter Leigh, Bams Abila, Stewart Bates, Jens Würthner, Vincent Meininger
Publié 2014Artigo -
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Variation in 5-hydroxymethylcytosine across human cortex and cerebellum par Katie Lunnon, Eilís Hannon, Rebecca G. Smith, Emma Dempster, Chloe C. Y. Wong, Joe Burrage, Claire Troakes, Safa Al‐Sarraj, Agnieszka Kepa, Leonard C. Schalkwyk, Jonathan Mill
Publié 2016Artigo -
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Co-deposition of SOD1, TDP-43 and p62 proteinopathies in ALS: evidence for multifaceted pathways underlying neurodegeneration par Benjamin G. Trist, Jennifer A. Fifita, Alison Hogan, Natalie Grima, Bradley Smith, Claire Troakes, Caroline Vance, Christopher E. Shaw, Safa Al‐Sarraj, Ian P. Blair, Kay L. Double
Publié 2022Artigo -
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Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD par Michael Niblock, Bradley Smith, Youn‐Bok Lee, Valentina Sardone, Simon Topp, Claire Troakes, Safa Al‐Sarraj, Claire S. Leblond, Patrick A. Dion, Guy A. Rouleau, Christopher E. Shaw, Jean‐Marc Gallo
Publié 2016Artigo -
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Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease par Adam R. Smith, Rebecca G. Smith, Ehsan Pishva, Eilís Hannon, Janou A. Y. Roubroeks, Joe Burrage, Claire Troakes, Safa Al‐Sarraj, Carolyn Sloan, Jonathan Mill, Daniël van den Hove, Katie Lunnon
Publié 2019Artigo -
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A Distinct Spectrum of Copy Number Aberrations in Pediatric High-Grade Gliomas par Dorine A. Bax, Alan Mackay, Suzanne E. Little, Diana Carvalho, Marta Viana‐Pereira, Narinder Tamber, Anita Grigoriadis, Alan Ashworth, Rui Manuel Reis, David W. Ellison, Safa Al‐Sarraj, Darren Hargrave, Chris Jones
Publié 2010Artigo -
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Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood par Matthew N Davies, Manuela Volta, Ruth Pidsley, Katie Lunnon, Abhishek Dixit, Simon Lovestone, Cristian Coarfa, R. Alan Harris, Aleksandar Milosavljevic, Claire Troakes, Safa Al‐Sarraj, Richard Dobson, Leonard C. Schalkwyk, Jonathan Mill
Publié 2012Artigo -
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Erratum: Has the survival of patients with glioblastoma changed over the years? par Ruth‐Mary deSouza, H Shaweis, Chengcheng Han, Vinothan Sivasubramaniam, L. Brazil, R. P. Beaney, G. Sadler, Safa Al‐Sarraj, Thomas H. Hampton, J. Logan, Victoria Hurwitz, Ranjeev Bhangoo, Richard Gullan, K. Ashkan
Publié 2016Errata/Corrigenda
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Dementia
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Amyotrophic lateral sclerosis
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Allele
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Cancer research
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Alzheimer's disease
Parkinson's disease
Single-nucleotide polymorphism
Dementia with Lewy bodies
Mutation
C9orf72
Frontotemporal lobar degeneration
Genetic association
Genome-wide association study
Neuropathology
DNA methylation
Gene expression
Glioma
Trinucleotide repeat expansion
Cell biology