Resultats de la cerca - Sachet A. Shukla

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  1. 1
    Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

    Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity per Michael S. Rooney, Sachet A. Shukla, Catherine J. Wu, Gad Getz, Nir Hacohen

    Publicat 2015
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  2. 2
    Clinical Validation of <i>PBRM1</i> Alterations as a Marker of Immune Checkpoint Inhibitor Response in Renal Cell Carcinoma

    Clinical Validation of <i>PBRM1</i> Alterations as a Marker of Immune Checkpoint Inhibitor Response in Renal Cell Carcinoma per David A. Braun, Yuko Ishii, Alice M. Walsh, Eliezer M. Van Allen, Catherine J. Wu, Sachet A. Shukla, Toni K. Choueiri

    Publicat 2019
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  3. 3
    Investigation of Antigen-Specific T-Cell Receptor Clusters in Human Cancers

    Investigation of Antigen-Specific T-Cell Receptor Clusters in Human Cancers per Hongyi Zhang, Longchao Liu, Jian Zhang, Jiahui Chen, Jianfeng Ye, Sachet A. Shukla, Jian Qiao, Xiaowei Zhan, Hao Chen, Catherine J. Wu, Yang‐Xin Fu, Bo Li

    Publicat 2019
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  4. 4
    Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer

    Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous... per Kyle C. Strickland, Brooke E. Howitt, Sachet A. Shukla, Scott J. Rodig, Lauren L. Ritterhouse, Joyce F. Liu, Judy E. Garber, Dipanjan Chowdhury, Catherine J. Wu, Alan D. D’Andrea, Ursula A. Matulonis, Panagiotis A. Konstantinopoulos

    Publicat 2016
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  5. 5
    Landscape of tumor-infiltrating T cell repertoire of human cancers

    Landscape of tumor-infiltrating T cell repertoire of human cancers per Bo Li, Taiwen Li, Jean‐Christophe Pignon, Binbin Wang, Jinzeng Wang, Sachet A. Shukla, Ruoxu Dou, Qianming Chen, F. Stephen Hodi, Toni K. Choueiri, Catherine J. Wu, Nir Hacohen, Sabina Signoretti, Jun S. Liu, X. Shirley Liu

    Publicat 2016
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  6. 6
    Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1

    Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1... per Brooke E. Howitt, Sachet A. Shukla, Lynette M. Sholl, Lauren L. Ritterhouse, Jaclyn C. Watkins, Scott J. Rodig, Elizabeth H. Stover, Kyle C. Strickland, Alan D. D’Andrea, Catherine J. Wu, Ursula A. Matulonis, Panagiotis A. Konstantinopoulos

    Publicat 2015
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  7. 7
    Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes

    Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes per Sachet A. Shukla, Michael S. Rooney, Mohini Rajasagi, Grace Tiao, Philip M. Dixon, Michael S. Lawrence, Jonathan Stevens, William J. Lane, Jamie L. DellaGatta, Scott Steelman, Carrie Sougnez, Kristian Cibulskis, Adam Kieżun, Nir Hacohen, Vladimir Brusić, Catherine J. Wu, Gad Getz

    Publicat 2015
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  8. 8
    STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

    STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA per An-Jou Chen, Ji-Hye Paik, Hailei Zhang, Sachet A. Shukla, Richard M. Mortensen, Jian Hu, Haoqiang Ying, Baoli Hu, Jessica A. Hurt, Natalie G. Farny, Caroline Dong, Yonghong Xiao, Y. Alan Wang, Pamela A. Silver, Lynda Chin, Shobha Vasudevan, Ronald A. DePinho

    Publicat 2012
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  9. 9
    A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression

    A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression per Kathleen M. Mahoney, Sachet A. Shukla, Nikolaos Patsoukis, Apoorvi Chaudhri, Edward P. Browne, Arnon Arazi, Thomas Eisenhaure, William F. Pendergraft, Ping Hua, Hung C. Pham, Xia Bu, Baogong Zhu, Nir Hacohen, Edward F. Fritsch, Vassiliki A. Boussiotis, Catherine J. Wu, Gordon J. Freeman

    Publicat 2018
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  10. 10
    HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study

    HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study per Vivek Naranbhai, Mathias Viard, Michael Dean, Stefan Groha, David A. Braun, Chris Labaki, Sachet A. Shukla, Yuko Yuki, Parantu K. Shah, Kevin M. Chin, Megan Wind‐Rotolo, Xinmeng Jasmine Mu, Paul B. Robbins, Alexander Gusev, Toni K. Choueiri, James L. Gulley, Mary Carrington

    Publicat 2021
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  11. 11
    Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

    Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia per Mohini Rajasagi, Sachet A. Shukla, Edward F. Fritsch, Derin B. Keskin, David S. DeLuca, Ellese M. Carmona, Wandi Zhang, Carrie Sougnez, Kristian Cibulskis, John Sidney, Kristen E. Stevenson, Jerome Ritz, Donna Neuberg, Vladimir Brusić, Stacey Gabriel, Eric S. Lander, Gad Getz, Nir Hacohen, Catherine J. Wu

    Publicat 2014
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  12. 12
    Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma

    Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma per Suzanne George, Diana Miao, George D. Demetri, Dennis O. Adeegbe, Scott J. Rodig, Sachet A. Shukla, Mikel Lipschitz, Ali Amin‐Mansour, Chandrajit P. Raut, Scott L. Carter, Peter S. Hammerman, Gordon J. Freeman, Catherine J. Wu, Patrick A. Ott, Kwok‐Kin Wong, Eliezer M. Van Allen

    Publicat 2017
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  13. 13
    <i>CDKN2A</i> Alterations and Response to Immunotherapy in Solid Tumors

    <i>CDKN2A</i> Alterations and Response to Immunotherapy in Solid Tumors per Elio Adib, Amin H. Nassar, Elie W. Akl, Sarah Abou Alaiwi, Pier Vitale Nuzzo, Tarek H. Mouhieddine, Guru Sonpavde, Robert I. Haddad, Kent W. Mouw, Marios Giannakis, F. Stephen Hodi, Sachet A. Shukla, Alexander Gusev, David A. Braun, Toni K. Choueiri, David J. Kwiatkowski

    Publicat 2021
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  14. 14
    Modeling clonal structure over narrow time frames via circulating tumor DNA in metastatic breast cancer

    Modeling clonal structure over narrow time frames via circulating tumor DNA in metastatic breast cancer per Zachary Weber, Katharine A. Collier, David Tallman, Juliet Forman, Sachet A. Shukla, Sarah Asad, Justin Rhoades, Samuel S. Freeman, Heather A. Parsons, Nicole Williams, Romualdo Barroso‐Sousa, Elizabeth H. Stover, Haider Mahdi, Carrie Cibulskis, Niall J. Lennon, Gavin Ha, Viktor A. Adalsteinsson, Sara M. Tolaney, Daniel G. Stover

    Publicat 2021
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  15. 15
    Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia

    Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia per Lili Wang, Jean Fan, Joshua M. Francis, George P. Georghiou, Sarah Hergert, Shuqiang Li, Rutendo Gambe, Chensheng W. Zhou, Chunxiao Yang, Sheng Xiao, Paola Dal Cin, Michaela Bowden, Dylan Kotliar, Sachet A. Shukla, Jennifer R. Brown, Donna Neuberg, Dario R. Alessi, Cheng‐Zhong Zhang, Peter V. Kharchenko, Kenneth J. Livak, Catherine J. Wu

    Publicat 2017
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  16. 16
    Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

    Genomic correlates of response to CTLA-4 blockade in metastatic melanoma per Eliezer M. Van Allen, Diana Miao, Bastian Schilling, Sachet A. Shukla, Christian U. Blank, Lisa Zimmer, Antje Sucker, Uwe Hillen, Marnix H. Geukes Foppen, Simone M. Goldinger, Jochen Utikal, Jessica C. Hassel, Benjamin Weide, Katharina C. Kaehler, Carmen Loquai, Peter Mohr, Ralf Gutzmer, Reinhard Dummer, Stacey Gabriel, Catherine J. Wu, Dirk Schadendorf, Levi A. Garraway

    Publicat 2015
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  17. 17
    microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-β Signaling in Glioblastoma

    microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-β Signaling in Glioblastoma per Giannicola Genovese, Ayla Ergün, Sachet A. Shukla, Benito Campos, Jason A. Hanna, Papia Ghosh, Steven N. Quayle, Kunal Rai, Simona Colla, Haoqiang Ying, Chang‐Jiun Wu, Sharmistha Sarkar, Yonghong Xiao, Jianhua Zhang, Hailei Zhang, Lawrence N. Kwong, Katherine L. Dunn, Wolf R. Wiedemeyer, Cameron Brennan, Hongwu Zheng, David L. Rimm, James J. Collins, Lynda Chin

    Publicat 2012
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  18. 18
    Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL

    Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL per Lili Wang, Alex K. Shalek, Robert Lawrence, Ruihua Ding, Jellert T. Gaublomme, Nathalie Pochet, Petar Stojanov, Carrie Sougnez, Sachet A. Shukla, Kristen E. Stevenson, Wandi Zhang, Jessica Wong, Quinlan Sievers, Bryan T. MacDonald, Alexander R. Vartanov, Natalie R. Goldstein, Donna Neuberg, Xi He, Eric S. Lander, Nir Hacohen, Aviv Regev, Gad Getz, Jennifer R. Brown, Hongkun Park, Catherine J. Wu

    Publicat 2014
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  19. 19
    irRECIST for the Evaluation of Candidate Biomarkers of Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma: Analysis of a Phase II Prospective Clinical Trial

    irRECIST for the Evaluation of Candidate Biomarkers of Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma: Analysis of a Phase II Prospective Clinical Trial per Jean‐Christophe Pignon, Opeyemi A. Jegede, Sachet A. Shukla, David A. Braun, Christine E. Horak, Megan Wind‐Rotolo, Yuko Ishii, Paul J. Catalano, Jonian Grosha, Abdallah Flaifel, Jesse Novak, Kathleen M. Mahoney, Gordon J. Freeman, Arlene H. Sharpe, F. Stephen Hodi, Robert J. Motzer, Toni K. Choueiri, Catherine J. Wu, Michael B. Atkins, David F. McDermott, Sabina Signoretti

    Publicat 2019
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  20. 20
    Expression of T-Cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma

    Expression of T-Cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma per Miriam Ficial, Opeyemi A. Jegede, Miriam Sant’Angelo, Yue Hou, Abdallah Flaifel, Jean‐Christophe Pignon, David A. Braun, Megan Wind‐Rotolo, Maura Sticco-Ivins, Paul J. Catalano, Gordon J. Freeman, Arlene H. Sharpe, F. Stephen Hodi, Robert J. Motzer, Catherine J. Wu, Michael B. Atkins, David F. McDermott, Sachet A. Shukla, Toni K. Choueiri, Sabina Signoretti

    Publicat 2020
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