Hakutulokset - Sachdev, Vinay

Intestine-specific DGAT1 deficiency improves atherosclerosis in apolipoprotein E knockout mice by reducing systemic cholesterol burden Tekijä Vujić, Nemanja, Korbelius, Melanie, Sachdev, Vinay, Rainer, Silvia, Zimmer, Andreas, Huber, Anton, Radović, Branislav, Kratky, Dagmar

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MiR-206 is expressed in pancreatic islets and regulates glucokinase activity Tekijä Vinod, Manjula, Patankar, Jay V., Sachdev, Vinay, Frank, Saša, Graier, Wolfgang F., Kratky, Dagmar, Kostner, Gerhard M.

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ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes Tekijä Korbelius, Melanie, Vujic, Nemanja, Sachdev, Vinay, Obrowsky, Sascha, Rainer, Silvia, Gottschalk, Benjamin, Graier, Wolfgang F., Kratky, Dagmar

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Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors Tekijä Dražić, Tonko, Sachdev, Vinay, Leopold, Christina, Patankar, Jay V., Malnar, Martina, Hećimović, Silva, Levak-Frank, Sanja, Habuš, Ivan, Kratky, Dagmar

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The PPARα Agonist Fenofibrate Prevents Formation of Protein Aggregates (Mallory-Denk bodies) in a Murine Model of Steatohepatitis-like Hepatotoxicity Tekijä Nikam, Aniket, Patankar, Jay V., Somlapura, Meghana, Lahiri, Pooja, Sachdev, Vinay, Kratky, Dagmar, Denk, Helmut, Zatloukal, Kurt, Abuja, Peter M.

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Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors Tekijä Dražić, Tonko, Molčanov, Krešimir, Sachdev, Vinay, Malnar, Martina, Hećimović, Silva, Patankar, Jay V., Obrowsky, Sascha, Levak-Frank, Sanja, Habuš, Ivan, Kratky, Dagmar

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Impaired Bile Acid Metabolism and Gut Dysbiosis in Mice Lacking Lysosomal Acid Lipase Tekijä Sachdev, Vinay, Duta-Mare, Madalina, Korbelius, Melanie, Vujić, Nemanja, Leopold, Christina, Freark de Boer, Jan, Rainer, Silvia, Fickert, Peter, Kolb, Dagmar, Kuipers, Folkert, Radovic, Branislav, Gorkiewicz, Gregor, Kratky, Dagmar

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Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation Tekijä Leopold, Christina, Duta-Mare, Madalina, Sachdev, Vinay, Goeritzer, Madeleine, Maresch, Lisa Katharina, Kolb, Dagmar, Reicher, Helga, Wagner, Bettina, Stojakovic, Tatjana, Ruelicke, Thomas, Haemmerle, Guenter, Hoefler, Gerald, Sattler, Wolfgang, Kratky, Dagmar

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Phospholipid Transfer Protein Is Expressed in Cerebrovascular Endothelial Cells and Involved in High Density Lipoprotein Biogenesis and Remodeling at the Blood-Brain Barrier Tekijä Chirackal Manavalan, Anil Paul, Kober, Alexandra, Metso, Jari, Lang, Ingrid, Becker, Tatjana, Hasslitzer, Karin, Zandl, Martina, Fanaee-Danesh, Elham, Pippal, Jyotsna Brijesh, Sachdev, Vinay, Kratky, Dagmar, Stefulj, Jasminka, Jauhiainen, Matti, Panzenboeck, Ute

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Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca(2+) Leak Directed to Mitochondria in Pancreatic Islets and β-Cells Tekijä Klec, Christiane, Madreiter-Sokolowski, Corina T., Stryeck, Sarah, Sachdev, Vinay, Duta-Mare, Madalina, Gottschalk, Benjamin, Depaoli, Maria R., Rost, Rene, Hay, Jesse, Waldeck-Weiermair, Markus, Kratky, Dagmar, Madl, Tobias, Malli, Roland, Graier, Wolfgang F.

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Active autophagy but not lipophagy in macrophages with defective lipolysis Tekijä Goeritzer, Madeleine, Vujic, Nemanja, Schlager, Stefanie, Chandak, Prakash G., Korbelius, Melanie, Gottschalk, Benjamin, Leopold, Christina, Obrowsky, Sascha, Rainer, Silvia, Doddapattar, Prakash, Aflaki, Elma, Wegscheider, Martin, Sachdev, Vinay, Graier, Wolfgang F., Kolb, Dagmar, Radovic, Branislav, Kratky, Dagmar

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Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism Tekijä Sachdev, Vinay, Leopold, Christina, Bauer, Raimund, Patankar, Jay V., Iqbal, Jahangir, Obrowsky, Sascha, Boverhof, Renze, Doktorova, Marcela, Scheicher, Bernhard, Goeritzer, Madeleine, Kolb, Dagmar, Turnbull, Andrew V., Zimmer, Andreas, Hoefler, Gerald, Hussain, M. Mahmood, Groen, Albert K., Kratky, Dagmar

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Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice Tekijä Gali, Chaitanya Chakravarthi, Fanaee-Danesh, Elham, Zandl-Lang, Martina, Albrecher, Nicole Maria, Tam-Amersdorfer, Carmen, Stracke, Anika, Sachdev, Vinay, Reichmann, Florian, Sun, Yidan, Avdili, Afrim, Reiter, Marielies, Kratky, Dagmar, Holzer, Peter, Lass, Achim, Kandimalla, Karunya K., Panzenboeck, Ute

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Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis Tekijä Duta-Mare, Madalina, Sachdev, Vinay, Leopold, Christina, Kolb, Dagmar, Vujic, Nemanja, Korbelius, Melanie, Hofer, Dina C., Xia, Wenmin, Huber, Katharina, Auer, Martina, Gottschalk, Benjamin, Magnes, Christoph, Graier, Wolfgang F., Prokesch, Andreas, Radovic, Branislav, Bogner-Strauss, Juliane G., Kratky, Dagmar

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Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis Tekijä Goeritzer, Madeleine, Schlager, Stefanie, Radovic, Branislav, Madreiter, Corina T., Rainer, Silvia, Thomas, Gwynneth, Lord, Caleb C., Sacks, Jessica, Brown, Amanda L., Vujic, Nemanja, Obrowsky, Sascha, Sachdev, Vinay, Kolb, Dagmar, Chandak, Prakash G., Graier, Wolfgang F., Sattler, Wolfgang, Brown, J. Mark, Kratky, Dagmar

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Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4 Tekijä Out, Carolien, Patankar, Jay V., Doktorova, Marcela, Boesjes, Marije, Bos, Trijnie, de Boer, Sanna, Havinga, Rick, Wolters, Henk, Boverhof, Renze, van Dijk, Theo H., Smoczek, Anna, Bleich, André, Sachdev, Vinay, Kratky, Dagmar, Kuipers, Folkert, Verkade, Henkjan J., Groen, Albert K.

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Defective Lipid Droplet–Lysosome Interaction Causes Fatty Liver Disease as Evidenced by Human Mutations in TMEM199 and CCDC115 Tekijä Larsen, Lars E., van den Boogert, Marjolein A.W., Rios-Ocampo, Wilson A., Jansen, Jos C., Conlon, Donna, Chong, Patrick L.E., Levels, J. Han M., Eilers, Roos E., Sachdev, Vinay V., Zelcer, Noam, Raabe, Tobias, He, Miao, Hand, Nicholas J., Drenth, Joost P.H., Rader, David J., Stroes, Eric S.G., Lefeber, Dirk J., Jonker, Johan W., Holleboom, Adriaan G.

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