نتائج البحث - Sabine Hadidaꝉ
- يعرض 1 - 4 نتائج من 4
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Discovery of <i>N</i>-(2,4-Di-<i>tert</i>-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (VX-770, Ivacaftor), a Potent and Orally Bioavailable CFTR Potentiator حسب Sabine Hadidaꝉ, Fredrick Van Goor, Jinglan Zhou, Vijayalaksmi Arumugam, Jason McCartney, Anna Hazlewood, Caroline J. Decker, Paul A. Negulescu, Peter D. J. Grootenhuis
منشور في 2014Artigo -
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Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809 حسب Fredrick Van Goor, Sabine Hadidaꝉ, Peter D. J. Grootenhuis, Bill Burton, Jeffrey H. Stack, Kimberly Straley, Caroline J. Decker, Mark A. Miller, Jason McCartney, Eric R. Olson, Jeffrey J. Wine, Ray A. Frizzell, Melissa A. Ashlock, Paul A. Negulescu
منشور في 2011Artigo -
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Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770 حسب Fredrick Van Goor, Sabine Hadidaꝉ, Peter D. J. Grootenhuis, Bill Burton, Dong Cao, Tim Neuberger, Amanda Turnbull, Ashvani K. Singh, John Joubran, Anna Hazlewood, Jinglan Zhou, Jason McCartney, Vijayalaksmi Arumugam, Caroline J. Decker, Jennifer Yang, Chris Young, Eric R. Olson, Jeffery J. Wine, Raymond A. Frizzell, Melissa A. Ashlock, Paul A. Negulescu
منشور في 2009Artigo
أدوات البحث:
موضوعات ذات صلة
Chemistry
Biochemistry
Cystic fibrosis transmembrane conductance regulator
Gene
Pharmacology
Biology
Cell biology
Chloride channel
Cystic fibrosis
Ivacaftor
Medicine
Molecular biology
Mutation
Potentiator
Secretion
Apical membrane
Benzazepines
Bioavailability
Biophysics
Carboxamide
Catalysis
Cell culture
Combinatorial chemistry
Endoplasmic reticulum
Epithelium
Extraction (chemistry)
Fluorocarbon
Gating
Genetics
In vitro