نتائج البحث - SEBOLT-LEOPOLD, JUDITH

Development of Preclinical Models to Understand and Treat Colorectal Cancer حسب Sebolt-Leopold, Judith S.

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THER-29. NOVEL DUAL EGFR/PI3-KINASE INHIBITORS SHOW ENHANCED POTENCY, STRONGER PATHWAY SUPPRESSION AND TARGETING OF METABOLIC PROPERTIES IN PEDIATRIC AND ADULT HIGH GRADE GLIOMA MO... حسب Sun, Yusha, Bailey, Cavan, Whitehead, Christopher, Sebolt-Leopold, Judith, Chandra, Joya

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Mapk Signaling Is Required for Dedifferentiation of Acinar Cells and Development of Pancreatic Intraepithelial Neoplasia in Mice حسب Collins, Meredith A., Yan, Wei, Sebolt–Leopold, Judith S., di Magliano, Marina Pasca

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A Role for K-ras in Conferring Resistance to the MEK Inhibitor, CI-1040 حسب Wang, Yuli, Van Becelaere, Keri, Jiang, Ping, Przybranowski, Sally, Omer, Charles, Sebolt-Leopold, Judith

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ERK activation is required for CCK-mediated pancreatic adaptive growth in mice حسب Holtz, Bryan J., Lodewyk, Kevin B., Sebolt-Leopold, Judith S., Ernst, Stephen A., Williams, John A.

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Cyclooxygenase-2 Influences Response to Co-Targeting of MEK and CDK4/6 in a Subpopulation of Pancreatic Cancers حسب Maust, Joel D., Frankowski-McGregor, Christy L., Bankhead, Armand, Simeone, Diane M., Sebolt-Leopold, Judith S.

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Compensatory pathways induced by MEK inhibition are effective drug targets for combination therapy against castration resistant prostate cancer حسب Gioeli, Daniel, Wunderlich, Winfried, Sebolt-Leopold, Judith, Bekiranov, Stefan, Wulfkuhle, Julia D., Petricoin, Emanuel F., Conaway, Mark, Weber, Michael J.

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Dual Inhibition of Allosteric Mitogen-Activated Protein Kinase (MEK) and Phosphatidylinositol 3-Kinase (PI3K) Oncogenic Targets with a Bifunctional Inhibitor حسب Van Dort, Marcian E., Galbán, Stefanie, Wang, Hanxiao, Sebolt-Leopold, Judith, Whitehead, Christopher, Hong, Hao, Rehemtulla, Alnawaz, Ross, Brian D.

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3′-Deoxy-3′-[(18)F]Fluorothymidine Positron Emission Tomography Is a Sensitive Method for Imaging the Response of BRAF-Dependent Tumors to MEK Inhibition حسب Solit, David B., Santos, Elmer, Pratilas, Christine A., Lobo, Jose, Moroz, Maxim, Cai, Shangde, Blasberg, Ronald, Sebolt-Leopold, Judith, Larson, Steven, Rosen, Neal

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Co-Targeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer حسب Williams, Terence M., Flecha, Athena R., Keller, Paul, Ram, Ashwin, Karnak, David, Galbán, Stefanie, Galbán, Craig J., Ross, Brian D., Lawrence, Theodore S., Rehemtulla, Alnawaz, Sebolt-Leopold, Judith

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The Effects of a Novel MEK Inhibitor PD184161 on MEK-ERK Signaling and Growth in Human Liver Cancer حسب Klein, Patrick J, Schmidt, C Max, Wiesenauer, Chad A, Choi, Jennifer N, Gage, Earl A, Yip-Schneider, Michele T, Wiebke, Eric A, Wang, Yufang, Omer, Charles, Sebolt-Leopold, Judith S

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Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency حسب Dosch, Joseph, Ziemke, Elizabeth, Wan, Shanshan, Luker, Kathryn, Welling, Theodore, Hardiman, Karin, Fearon, Eric, Thomas, Suneetha, Flynn, Matthew, Rios-Doria, Jonathan, Hollingsworth, Robert, Herbst, Ronald, Hurt, Elaine, Sebolt-Leopold, Judith

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Costello and Cardio-Facio-Cutaneous Syndromes: Moving Toward Clinical Trials in RASopathies حسب RAUEN, KATHERINE A., BANERJEE, ANURADHA, BISHOP, W. ROBERT, LAUCHLE, JENNIFER O., MCCORMICK, FRANK, MCMAHON, MARTIN, MELESE, TERI, MUNSTER, PAMELA N., NADAF, SORENA, PACKER, ROGER J., SEBOLT-LEOPOLD, JUDITH, VISKOCHIL, DAVID H.

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Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor حسب Ramkumar, Kavya, Samanta, Soma, Kyani, Anahita, Yang, Suhui, Tamura, Shuzo, Ziemke, Elizabeth, Stuckey, Jeanne A., Li, Si, Chinnaswamy, Krishnapriya, Otake, Hiroyuki, Debnath, Bikash, Yarovenko, Vladimir, Sebolt-Leopold, Judith S., Ljungman, Mats, Neamati, Nouri

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Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1() حسب Zhang, Huabing, Ramakrishnan, Sadeesh K., Triner, Daniel, Centofanti, Brook, Maitra, Dhiman, Győrffy, Balázs, Sebolt-Leopold, Judith S., Dame, Michael K., Varani, James, Brenner, Dean E., Fearon, Eric R., Omary, M. Bishr, Shah, Yatrik M.

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Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon حسب Haigis, Kevin M, Kendall, Krystle R, Wang, Yufang, Cheung, Ann, Haigis, Marcia C, Glickman, Jonathan N, Niwa-Kawakita, Michiko, Sweet-Cordero, Alejandro, Sebolt-Leopold, Judith, Shannon, Kevin M, Settleman, Jeffrey, Giovannini, Marco, Jacks, Tyler

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Prospective analysis of parametric MRI biomarkers: Identification of early and distinct glioma response patterns not predicted by standard radiographic assessment حسب Galbán, Craig J., Chenevert, Thomas L., Meyer, Charles R., Tsien, Christina, Lawrence, Theodore S., Hamstra, Daniel A., Junck, Larry, Sundgren, Pia C., Johnson, Timothy D., Galbán, Stefanie, Sebolt-Leopold, Judith S., Rehemtulla, Alnawaz, Ross, Brian D.

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BRAF mutation predicts sensitivity to MEK inhibition حسب Solit, David B., Garraway, Levi A., Pratilas, Christine A., Sawai, Ayana, Getz, Gad, Basso, Andrea, Ye, Qing, Lobo, Jose M., She, Yuhong, Osman, Iman, Golub, Todd R., Sebolt-Leopold, Judith, Sellers, William R., Rosen, Neal

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Response and Resistance to MEK Inhibition in Leukaemias Initiated by Hyperactive Ras حسب Lauchle, Jennifer O., Kim, Doris, Le, Doan T., Akagi, Keiko, Crone, Michael, Krisman, Kimberly, Warner, Kegan, Bonifas, Jeannette M., Li, Qing, Coakley, Kristin M., Diaz-Flores, Ernesto, Gorman, Matthew, Przybranowski, Sally, Tran, Mary, Kogan, Scott C., Roose, Jeroen P., Copeland, Neal, Jenkins, Nancy, Parada, Luis, Wolff, Linda, Sebolt-Leopold, Judith, Shannon, Kevin

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Proceedings from the 2009 Genetic Syndromes of the Ras/MAPK Pathway: From Bedside to Bench and Back حسب Rauen, Katherine A., Schoyer, Lisa, McCormick, Frank, Lin, Angela E., Allanson, Judith E., Stevenson, David A., Gripp, Karen W., Neri, Giovanni, Carey, John C., Legius, Eric, Tartaglia, Marco, Schubbert, Suzanne, Roberts, Amy E., Gelb, Bruce D., Shannon, Kevin, Gutmann, David H., McMahon, Martin, Guerra, Carmen, Fagin, James A., Yu, Benjamin, Aoki, Yoko, Neel, Ben G., Balmain, Allan, Drake, Richard R., Nolan, Garry P., Zenker, Martin, Bollag, Gideon, Sebolt-Leopold, Judith, Gibbs, Jackson B., Silva, Alcino J., Patton, E. Elizabeth, Viskochil, David H., Kieran, Mark W., Korf, Bruce R., Hagerman, Randi J., Packer, Roger J., Melese, Teri

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