Výsledky vyhledávání - Ryan L. Kelly

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  1. 1
    Reduction of Nonspecificity Motifs in Synthetic Antibody Libraries

    Reduction of Nonspecificity Motifs in Synthetic Antibody Libraries Autor Ryan L. Kelly, Doris Le, Jessie Zhao, K. Dane Wittrup

    Vydáno 2017
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    Artigo
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  2. 2
    Human Protein Arginine Methyltransferase 7 (PRMT7) Is a Type III Enzyme Forming ω-N-Monomethylated Arginine Residues

    Human Protein Arginine Methyltransferase 7 (PRMT7) Is a Type III Enzyme Forming ω-N-Monomethylated Arginine Residues Autor Cecilia I. Zurita‐Lopez, Troy E. Sandberg, Ryan L. Kelly, Steven Clarke

    Vydáno 2012
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    Artigo
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  3. 3
    A switchable yeast display/secretion system

    A switchable yeast display/secretion system Autor James A. Van Deventer, Ryan L. Kelly, Saravanan Rajan, K. Dane Wittrup, Sachdev S. Sidhu

    Vydáno 2015
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  4. 4
    The CD28 Transmembrane Domain Contains an Essential Dimerization Motif

    The CD28 Transmembrane Domain Contains an Essential Dimerization Motif Autor Scott A. Leddon, Margaret M. Fettis, Kristin Abramo, Ryan L. Kelly, David Oleksyn, Jim Miller

    Vydáno 2020
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  5. 5
    Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin

    Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic targ... Autor András Perl, Robert Hanczko, Zhi‐Wei Lai, Zachary Oaks, Ryan L. Kelly, Rebecca Borsuk, John M. Asara, Paul E. M. Phillips

    Vydáno 2015
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  6. 6
    Target-independent variable region mediated effects on antibody clearance can be FcRn independent

    Target-independent variable region mediated effects on antibody clearance can be FcRn independent Autor Ryan L. Kelly, Yao Yu, Tingwan Sun, Isabelle Caffry, Heather Lynaugh, Michael E. Brown, Tushar Jain, Yingda Xu, K. Dane Wittrup

    Vydáno 2016
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  7. 7
    PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145

    PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145 Autor Yanzhong Yang, Andrea Hadjikyriacou, Zheng Xia, Sitaram Gayatri, Daehoon Kim, Cecilia I. Zurita‐Lopez, Ryan L. Kelly, Ailan Guo, Wei Li, Steven Clarke, Mark T. Bedford

    Vydáno 2015
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  8. 8
    High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice

    High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice Autor Ryan L. Kelly, Tingwan Sun, Tushar Jain, Isabelle Caffry, Yao Yu, Yuan Cao, Heather Lynaugh, Michael E. Brown, Maximiliano Vásquez, K. Dane Wittrup, Yingda Xu

    Vydáno 2015
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  9. 9
    An engineered antibody binds a distinct epitope and is a potent inhibitor of murine and human VISTA

    An engineered antibody binds a distinct epitope and is a potent inhibitor of murine and human VISTA Autor Nishant Mehta, Sainiteesh Maddineni, Ryan L. Kelly, Robert Lee, Sean A. Yamada‐Hunter, John L. Silberstein, R. Andres Parra Sperberg, Caitlyn L. Miller, Amanda Rabe, Louai Labanieh, Jennifer R. Cochran

    Vydáno 2020
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  10. 10
    Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus

    Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus Autor Iwona A. Buskiewicz, Theresa L. Montgomery, Elizabeth C. Yasewicz, Sally A. Huber, Michael P. Murphy, Richard C. Hartley, Ryan L. Kelly, Mary K. Crow, András Perl, Ralph C. Budd, Andreas Koenig

    Vydáno 2016
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  11. 11
    Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial

    Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial Autor Zhi‐Wei Lai, Ryan L. Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcı́a, Hajra Tily, Lisa Francis, Stephen V. Faraone, Paul E. M. Phillips, András Perl

    Vydáno 2018
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  12. 12
    Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis

    Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis Autor Zachary Oaks, Akshay Patel, Nick Huang, G. Choudhary, Thomas Winans, T. Faludi, Dániel Krakkó, Maria F. Duarte, Jacob S. Lewis, Miguel Beckford, Sampson Lee Blair, Ryan L. Kelly, S.K. Landas, Frank A. Middleton, John M. Asara, S. K. Chung, David Fernández, Katalin Bánki, András Perl

    Vydáno 2023
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  13. 13
    Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

    Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses Autor Kelly D. Moynihan, Cary F. Opel, Gregory L. Szeto, Alice Tzeng, Eric F. Zhu, J Engreitz, Christina Williamson, Kavya Rakhra, Michael H. Zhang, Adrienne M. Rothschilds, Sudha Kumari, Ryan L. Kelly, Byron H. Kwan, Wuhbet Abraham, Kevin Hu, Naveen K. Mehta, Monique J. Kauke, Heikyung Suh, Jennifer R. Cochran, Douglas A. Lauffenburger, K. Dane Wittrup, Darrell J. Irvine

    Vydáno 2016
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  14. 14
    Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury

    Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury Autor Nobuhiko Kayagaki, Irma B. Stowe, Kamela Alegre, Ishan Deshpande, Shuang Wu, Zhonghua Lin, Opher S. Kornfeld, Bettina L. Lee, Juan Zhang, John Liu, Eric Suto, Wyne P. Lee, Kellen Schneider, Wei‐Yu Lin, Dhaya Seshasayee, Tushar Bhangale, Cécile Chalouni, Matthew C. Johnson, Prajakta Joshi, Jan Mossemann, Sarah Zhao, D Israf Ali, Neil M. Goldenberg, Blayne A. Sayed, Benjamin E. Steinberg, Kim Newton, Joshua D. Webster, Ryan L. Kelly, Vishva M. Dixit

    Vydáno 2023
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  15. 15
    Lab-in-the-loop therapeutic antibody design with deep learning

    Lab-in-the-loop therapeutic antibody design with deep learning Autor Nathan C. Frey, Isidro Hötzel, Samuel D Stanton, Ryan L. Kelly, Robert G. Alberstein, Emily K. Makowski, Karolis Martinkus, Daniel Berenberg, Jack Bevers, Tyler Bryson, Pamela Chan, Alicja Czubaty, Tamica A D'Souza, Henri Dwyer, Anna Dziewulska, J.W. Fairman, Allen Goodman, Jennifer L. Hofmann, Henry H Isaacson, Aya Abdelsalam Ismail, S. Joseph James, Taylor Joren, Simon Kelow, James R. Kiefer, Matthieu Kirchmeyer, Joseph Kleinhenz, James T. Koerber, Julien Lafrance‐Vanasse, Andrew Leaver‐Fay, Jae Hyeon Lee, E. Lee, D. Lee, Wei‐Ching Liang, J. Lin, Sidney Lisanza, Andreas Loukas, Jan Ludwiczak, Sai Pooja Mahajan, Omar Mahmood, Homa MohammadiPeyhani, Santrupti Nerli, Ji Won Park, Jaewoo Park, Stephen Ra, Sarah A. Robinson, Saeed Saremi, Franziska Seeger, Indrajit Sinha, Anna M. Sokòl, Christoph Spiess, Nataša Tagasovska, Ho To, Edward Wagstaff, Amy Wang, Andrew M. Watkins, Blair Wilson, Shuang Wu, Karina Zadorozhny, John C. Marioni, Aviv Regev, Yan Wu, Kyunghyun Cho, Richard Bonneau, Vladimir Gligorijević

    Vydáno 2025
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