Výsledky vyhledávání - Ruth Riisnaes

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  1. 1
    Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer

    Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Pro... Autor Jonathan Welti, Daniel Nava Rodrigues, Adam Sharp, Shihua Sun, David Lorente, Ruth Riisnaes, Ines Figueiredo, Zafeiris Zafeiriou, Pasquale Rescigno, Johann S. de Bono, Stephen R. Plymate

    Vydáno 2016
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  2. 2
    Visceral Disease in Castration-resistant Prostate Cancer

    Visceral Disease in Castration-resistant Prostate Cancer Autor Carmel Pezaro, Aurelius Omlin, David Lorente, Daniel Nava Rodrigues, Roberta Ferraldeschi, Diletta Bianchini, Deborah Mukherji, Ruth Riisnaes, Amelia Altavilla, Mateus Crespo, Nina Tunariu, Johann S. de Bono, Gerhardt Attard

    Vydáno 2013
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  3. 3
    Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer

    Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer Autor Susan F. Slovin, Syed A. Hussain, Fred Saad, Jorge García, Joel Picus, Roberta Ferraldeschi, Mateus Crespo, Penelope Flohr, Ruth Riisnaes, Chih‐Che Lin, Harold Keer, Aram Oganesian, Paul Workman, Johann S. de Bono

    Vydáno 2019
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  4. 4
    Novel, gross chromosomal alterations involving PTEN cooperate with allelic loss in prostate cancer

    Novel, gross chromosomal alterations involving PTEN cooperate with allelic loss in prostate cancer Autor Alison Reid, Gerhardt Attard, Daniel Brewer, Susana Miranda, Ruth Riisnaes, Jeremy Clark, Lucy Hylands, Sue Merson, Roy Vergis, Charles Jameson, S. Høyer, Karina Dalsgaard Sørenson, Michael Borre, Chris Jones, Johann S. de Bono, Colin S. Cooper

    Vydáno 2012
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  5. 5
    Circulating Tumor Cell Biomarker Panel As an Individual-Level Surrogate for Survival in Metastatic Castration-Resistant Prostate Cancer

    Circulating Tumor Cell Biomarker Panel As an Individual-Level Surrogate for Survival in Metastatic Castration-Resistant Prostate Cancer Autor Howard I. Scher, Glenn Heller, Arturo Molina, Gerhardt Attard, Daniel C. Danila, Xiaoyu Jia, Weimin Peng, Shahneen Sandhu, David Olmos, Ruth Riisnaes, Robert G. McCormack, Tomasz Burzykowski, Thian Kheoh, Martin Fleisher, Marc Buyse, Johann S. de Bono

    Vydáno 2015
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  6. 6
    First-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate cancer

    First-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate can... Autor Diletta Bianchini, Aurelius Omlin, Carmel Pezaro, David Lorente, Roberta Ferraldeschi, Deborah Mukherji, Mateus Crespo, I. Figueiredo, Susana Miranda, Ruth Riisnaes, Andrea Zivi, Aby Buchbinder, Dana E. Rathkopf, Gerhardt Attard, Howard I. Scher, Johann S. de Bono, Daniel C. Danila

    Vydáno 2013
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  7. 7
    Androgen receptor expression in circulating tumour cells from castration-resistant prostate cancer patients treated with novel endocrine agents

    Androgen receptor expression in circulating tumour cells from castration-resistant prostate cancer patients treated with novel endocrine agents Autor Mateus Crespo, Guus van Dalum, Roberta Ferraldeschi, Zafeiris Zafeiriou, Spyridon Sideris, David Lorente, Diletta Bianchini, Daniel Nava Rodrigues, Ruth Riisnaes, Susana Miranda, I. Figueiredo, Penelope Flohr, Karolina Nowakowska, Johann S. de Bono, Leon W.M.M. Terstappen, Gerhardt Attard

    Vydáno 2015
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  8. 8
    First-in-Human Study of CH5132799, an Oral Class I PI3K Inhibitor, Studying Toxicity, Pharmacokinetics, and Pharmacodynamics, in Patients with Metastatic Cancer

    First-in-Human Study of CH5132799, an Oral Class I PI3K Inhibitor, Studying Toxicity, Pharmacokinetics, and Pharmacodynamics, in Patients with Metastatic Cancer Autor Sarah P. Blagden, Aurelius Olmin, Debra H. Josephs, Chara Stavraka, Andrea Zivi, David J. Pinato, Alan Anthoney, Shaun Decordova, Karen E. Swales, Ruth Riisnaes, Lorna Pope, Kohei Noguchi, Rie Shiokawa, Michiyasu Inatani, Jenny Prince, Keith Jones, Chris Twelves, James Spicer, Udai Banerji

    Vydáno 2014
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  9. 9
    Randomized Phase II Study Evaluating Akt Blockade with Ipatasertib, in Combination with Abiraterone, in Patients with Metastatic Prostate Cancer with and without PTEN Loss

    Randomized Phase II Study Evaluating Akt Blockade with Ipatasertib, in Combination with Abiraterone, in Patients with Metastatic Prostate Cancer with and without PTEN Loss Autor Johann S. de Bono, Ugo De Giorgi, Daniel Nava Rodrigues, Christophe Massard, Sergio Bracarda, Albert Font, José Ángel Arranz Arija, Kent C. Shih, George Daniel Rădăvoi, Na Xu, Wai Yee Chan, Han Ma, Steven Gendreau, Ruth Riisnaes, Premal H. Patel, Daniel Maslyar, Viorel Jinga

    Vydáno 2018
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  10. 10
    Multi-Purpose Utility of Circulating Plasma DNA Testing in Patients with Advanced Cancers

    Multi-Purpose Utility of Circulating Plasma DNA Testing in Patients with Advanced Cancers Autor Géraldine Perkins, Timothy A. Yap, Lorna Pope, Amy Mulick, Juliet Dukes, Ruth Riisnaes, Christophe Massard, Philippe A. Cassier, Susana Miranda, Jeremy Clark, Katie Ann Denholm, Khin Thway, David González de Castro, Gerhardt Attard, L Rhoda Molife, Stan B. Kaye, Udai Banerji, Johann S. de Bono

    Vydáno 2012
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  11. 11
    PTEN loss as a predictive biomarker for the Akt inhibitor ipatasertib combined with abiraterone acetate in patients with metastatic castration-resistant prostate cancer (mCRPC)

    PTEN loss as a predictive biomarker for the Akt inhibitor ipatasertib combined with abiraterone acetate in patients with metastatic castration-resistant prostate cancer (mCRPC) Autor Johann S. de Bono, Ugo De Giorgi, Christophe Massard, Sergio Bracarda, Daniel Nava Rodrigues, Ivo Kocák, Albert Font, J.Á. Arranz Arija, Kent C. Shih, George Daniel Rădăvoi, Wandong Yu, Wen‐Ching Chan, Steven Gendreau, L. Zhang, Ruth Riisnaes, Matthew Wongchenko, Daniel Maslyar, Viorel Jinga

    Vydáno 2016
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  12. 12
    RB1 Heterogeneity in Advanced Metastatic Castration-Resistant Prostate Cancer

    RB1 Heterogeneity in Advanced Metastatic Castration-Resistant Prostate Cancer Autor Daniel Nava Rodrigues, Nicola Casiraghi, Alessandro Romanel, Mateus Crespo, Susana Miranda, Pasquale Rescigno, Ines Figueiredo, Ruth Riisnaes, Suzanne Carreira, Semini Sumanasuriya, Paola Gasperini, Adam Sharp, Joaquı́n Mateo, Alan Makay, Christopher McNair, Matthew J. Schiewer, Karen E. Knudsen, Gunther Boysen, Francesca Demichelis, Johann S. de Bono

    Vydáno 2018
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  13. 13
    Efficacy and Safety of Weekly Paclitaxel Plus Vistusertib vs Paclitaxel Alone in Patients With Platinum-Resistant Ovarian High-Grade Serous Carcinoma

    Efficacy and Safety of Weekly Paclitaxel Plus Vistusertib vs Paclitaxel Alone in Patients With Platinum-Resistant Ovarian High-Grade Serous Carcinoma Autor Susana Banerjee, Gaia Giannone, Andrew R. Clamp, Darren Ennis, Rosalind Glasspool, Rebecca Herbertson, Jonathan Krell, Ruth Riisnaes, Hasan Mirza, Zhao Cheng, Jacqueline McDermott, Clare Green, Rebecca Kristeleit, Angela George, Charlie Gourley, Liz-Anne Lewsley, Debbie Rai, Udai Banerji, Samantha Hinsley, Iain A. McNeish

    Vydáno 2023
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  14. 14
    Genomic Analysis of Three Metastatic Prostate Cancer Patients with Exceptional Responses to Carboplatin Indicating Different Types of DNA Repair Deficiency

    Genomic Analysis of Three Metastatic Prostate Cancer Patients with Exceptional Responses to Carboplatin Indicating Different Types of DNA Repair Deficiency Autor Zafeiris Zafeiriou, Diletta Bianchini, Robert W. Chandler, Pasquale Rescigno, Wei Yuan, Suzanne Carreira, Maialen Barrero, Antonella Petremolo, Susana Miranda, Ruth Riisnaes, Daniel Nava Rodrigues, Bora Gürel, Semini Sumanasuriya, Alec Paschalis, Adam Sharp, Joaquı́n Mateo, Nina Tunariu, Arul M. Chinnaiyan, Colin C. Pritchard, Kevin Kelly, Johann S. de Bono

    Vydáno 2018
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  15. 15
    Prostate-specific Membrane Antigen Heterogeneity and DNA Repair Defects in Prostate Cancer

    Prostate-specific Membrane Antigen Heterogeneity and DNA Repair Defects in Prostate Cancer Autor Alec Paschalis, Beshara Sheehan, Ruth Riisnaes, Daniel Nava Rodrigues, Bora Gürel, Cláudia Bertan, Ana Ferreira, Maryou B. Lambros, George Seed, Wei Yuan, David Dolling, Jon Welti, Antje Neeb, Semini Sumanasuriya, Pasquale Rescigno, Diletta Bianchini, Nina Tunariu, Suzanne Carreira, Adam Sharp, Wim J.G. Oyen, Johann S. de Bono

    Vydáno 2019
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  16. 16
    Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells

    Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells Autor Roberta Ferraldeschi, Jonathan Welti, Marissa Powers, Wei Yuan, Tomoko Smyth, George Seed, Ruth Riisnaes, Somaieh Hedayat, Hannah Wang, Mateus Crespo, Daniel Nava Rodrigues, Ines Figueiredo, Susana Miranda, Suzanne Carreira, John F. Lyons, Swee Y. Sharp, Stephen R. Plymate, Gerhardt Attard, Nicola G. Wallis, Paul Workman, Johann S. de Bono

    Vydáno 2016
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  17. 17
    Phase I Trial of a Selective c-MET Inhibitor ARQ 197 Incorporating Proof of Mechanism Pharmacodynamic Studies

    Phase I Trial of a Selective c-MET Inhibitor ARQ 197 Incorporating Proof of Mechanism Pharmacodynamic Studies Autor Timothy A. Yap, David Olmos, André T. Brunetto, Nina Tunariu, Jorge Barriuso, Ruth Riisnaes, Lorna Pope, J. W. Clark, P. Andrew Futreal, Michael Germuska, David J. Collins, Nandita M. deSouza, Martin O. Leach, Ronald E. Savage, Carol Waghorne, Feng Chai, Edward G. Garmey, Brian Schwartz, Stan B. Kaye, Johann S. de Bono

    Vydáno 2011
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  18. 18
    PTEN loss in circulating tumour cells correlates with PTEN loss in fresh tumour tissue from castration-resistant prostate cancer patients

    PTEN loss in circulating tumour cells correlates with PTEN loss in fresh tumour tissue from castration-resistant prostate cancer patients Autor Elizabeth A. Punnoose, Roberta Ferraldeschi, Edith Szafer‐Glusman, Eric Tucker, Sankar Mohan, Penelope Flohr, Ruth Riisnaes, Susana Miranda, Ines Figueiredo, Daniel Nava Rodrigues, Aurelius Omlin, Carmel Pezaro, Jin Zhu, Lukas C. Amler, Premal H. Patel, Yibing Yan, Natalee Bales, Shannon L. Werner, Jessica Louw, Ajay Pandita, Dena Marrinucci, Gerhardt Attard, Johann S. de Bono

    Vydáno 2015
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  19. 19
    PTEN Protein Loss and Clinical Outcome from Castration-resistant Prostate Cancer Treated with Abiraterone Acetate

    PTEN Protein Loss and Clinical Outcome from Castration-resistant Prostate Cancer Treated with Abiraterone Acetate Autor Roberta Ferraldeschi, Daniel Nava Rodrigues, Ruth Riisnaes, Susana Miranda, Ines Figueiredo, Pasquale Rescigno, Praful Ravi, Carmel Pezaro, Aurelius Omlin, David Lorente, Zafeiris Zafeiriou, Joaquı́n Mateo, Amelia Altavilla, Spyridon Sideris, Diletta Bianchini, Emily Grist, Khin Thway, Raquel Pérez-López, Nina Tunariu, Chris Parker, David P. Dearnaley, Alison Reid, Gerhardt Attard, Johann S. de Bono

    Vydáno 2014
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  20. 20
    Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer

    Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer Autor Adam Sharp, Ilsa M. Coleman, Wei Yuan, Cynthia C.T. Sprenger, David Dolling, Daniel Nava Rodrigues, Joshua W. Russo, Ines Figueiredo, Cláudia Bertan, George Seed, Ruth Riisnaes, Takuma Uo, Antje Neeb, Jonathan Welti, Colm Morrissey, Suzanne Carreira, Jun Luo, Peter S. Nelson, Steven P. Balk, Lawrence D. True, Johann S. de Bono, Stephen R. Plymate

    Vydáno 2018
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