Search Results - Ruby L.C. Hoo

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  1. 1
    The Novel Perspectives of Adipokines on Brain Health

    The Novel Perspectives of Adipokines on Brain Health by Thomas H. Lee, Kenneth K.Y. Cheng, Ruby L.C. Hoo, Parco M. Siu, Suk-Yu Yau

    Published 2019
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  2. 2
    Growth Hormone Induces Hepatic Production of Fibroblast Growth Factor 21 through a Mechanism Dependent on Lipolysis in Adipocytes

    Growth Hormone Induces Hepatic Production of Fibroblast Growth Factor 21 through a Mechanism Dependent on Lipolysis in Adipocytes by Wei Chen, Ruby L.C. Hoo, Morichika Konishi, Nobuyuki Itoh, Pui-chi Lee, Hongying Ye, Karen S.L. Lam, Aimin Xu

    Published 2011
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  3. 3
    APPL1 potentiates insulin secretion in pancreatic β cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in mice

    APPL1 potentiates insulin secretion in pancreatic β cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in mice by Kenneth K.Y. Cheng, Karen S.L. Lam, Donghai Wu, Yu Wang, Gary Sweeney, Ruby L.C. Hoo, Jialiang Zhang, Aimin Xu

    Published 2012
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  4. 4
    Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia

    Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia by Xiaowen Huang, Pengju Wei, Cheng Fang, Min Yu, Shilun Yang, Linhui Qiu, Yu Wang, Aimin Xu, Ruby L.C. Hoo, Junlei Chang

    Published 2024
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  5. 5
    The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages

    The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages by Kelvin Ka Lok Wu, Kekao Long, Huige Lin, Parco M. Siu, Ruby L.C. Hoo, Dewei Ye, Aimin Xu, Kenneth K.Y. Cheng

    Published 2021
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  6. 6
    Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin

    Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin by Suk-Yu Yau, Ang Li, Ruby L.C. Hoo, Ching C. Lau, Brian R. Christie, Tatia M.C. Lee, Aimin Xu, Kwok‐Fai So

    Published 2014
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  7. 7
    Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation

    Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation by Yong Pan, Xiaoyan Hui, Ruby L.C. Hoo, Dewei Ye, Cyrus Yuk Cheung Chan, Tianshi Feng, Yu Wang, Karen Siu Ling Lam, Aimin Xu

    Published 2019
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  8. 8
    Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury

    Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury by Mingyan Zhou, Aimin Xu, Paul Kwong Hang Tam, Karen S.L. Lam, Lawrence Chan, Ruby L.C. Hoo, Jing Liu, Hei‐Man Chow, Yu Wang

    Published 2008
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  9. 9
    Adipocyte-derived shed Syndecan-4 suppresses lipolysis contributing to impaired adipose tissue browning and adaptive thermogenesis

    Adipocyte-derived shed Syndecan-4 suppresses lipolysis contributing to impaired adipose tissue browning and adaptive thermogenesis by Jiuyu Zong, Xiaoping Wu, Xiaowen Huang, Lufengzi Yuan, Kai Yuan, Zixuan Zhang, Mengxue Jiang, Zhihui Ping, Lai Yee Cheong, Aimin Xu, Ruby L.C. Hoo

    Published 2025
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  10. 10
    Adiponectin Modulates the Glycogen Synthase Kinase-3β/β-Catenin Signaling Pathway and Attenuates Mammary Tumorigenesis of MDA-MB-231 Cells in Nude Mice

    Adiponectin Modulates the Glycogen Synthase Kinase-3β/β-Catenin Signaling Pathway and Attenuates Mammary Tumorigenesis of MDA-MB-231 Cells in Nude Mice by Yu Wang, Janice B. B. Lam, Karen S.L. Lam, Jing Liu, Michael C. Lam, Ruby L.C. Hoo, Donghai Wu, Garth J. S. Cooper, Aimin Xu

    Published 2006
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  11. 11
    A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes

    A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes by Lingling Shu, Ruby L.C. Hoo, Xiaoping Wu, Yong Pan, Ida P. C. Lee, Lai Yee Cheong, Stefan R. Bornstein, Xianglu Rong, Jiao Guo, Aimin Xu

    Published 2017
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  12. 12
    An MMP-9 exclusive neutralizing antibody attenuates blood-brain barrier breakdown in mice with stroke and reduces stroke patient-derived MMP-9 activity

    An MMP-9 exclusive neutralizing antibody attenuates blood-brain barrier breakdown in mice with stroke and reduces stroke patient-derived MMP-9 activity by Yabin Ji, Qiang Gao, Yinzhong Ma, F. Wang, Xixi Tan, Dengpan Song, Ruby L.C. Hoo, Zening Wang, Xin Ge, Hongjie Han, Fuyou Guo, Junlei Chang

    Published 2023
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  13. 13
    Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes

    Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes by K. C. B. Tan, Wing-Sun Chow, Annette W.K. Tso, A Xu, Hung‐Fat Tse, Ruby L.C. Hoo, D. J. Betteridge, Karen S.L. Lam

    Published 2007
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  14. 14
    Selective Elevation of Adiponectin Production by the Natural Compounds Derived from a Medicinal Herb Alleviates Insulin Resistance and Glucose Intolerance in Obese Mice

    Selective Elevation of Adiponectin Production by the Natural Compounds Derived from a Medicinal Herb Alleviates Insulin Resistance and Glucose Intolerance in Obese Mice by Aimin Xu, Hongbing Wang, Ruby L.C. Hoo, Gary Sweeney, Paul M. Vanhoutte, Yu Wang, Donghai Wu, Wen‐Jing Chu, Guo‐Wei Qin, Karen S.L. Lam

    Published 2008
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  15. 15
    Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway

    Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway by Junlei Chang, Yiming Li, Yü Huang, Karen S.L. Lam, Ruby L.C. Hoo, Wing Tak Wong, Kenneth K.Y. Cheng, Yiqun Wang, Paul M. Vanhoutte, Aimin Xu

    Published 2010
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  16. 16
    Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells

    Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellat... by Xiaoping Wu, Lingling Shu, Zixuan Zhang, Jingjing Li, Jiuyu Zong, Lai Yee Cheong, Dewei Ye, Karen S.L. Lam, Erfei Song, Cunchuan Wang, Aimin Xu, Ruby L.C. Hoo

    Published 2021
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  17. 17
    Adiponectin Is Required for PPARγ-Mediated Improvement of Endothelial Function in Diabetic Mice

    Adiponectin Is Required for PPARγ-Mediated Improvement of Endothelial Function in Diabetic Mice by Wing Tak Wong, Xiao Yu Tian, Aimin Xu, Jun Yu, Chi Wai Lau, Ruby L.C. Hoo, Yu Wang, Vivian Lee, Karen S.L. Lam, Paul M. Vanhoutte, Yü Huang

    Published 2011
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  18. 18
    Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice

    Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice by Aimin Xu, Michael C. Lam, Kok Weng Chan, Yu Wang, Jialiang Zhang, Ruby L.C. Hoo, Jian Xu, Baoying Chen, Wing-Sun Chow, Annette W.K. Tso, Karen S.L. Lam

    Published 2005
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  19. 19
    Testosterone Selectively Reduces the High Molecular Weight Form of Adiponectin by Inhibiting Its Secretion from Adipocytes

    Testosterone Selectively Reduces the High Molecular Weight Form of Adiponectin by Inhibiting Its Secretion from Adipocytes by Aimin Xu, Kok Weng Chan, Ruby L.C. Hoo, Yu Wang, Kathryn Choon Beng Tan, Jialiang Zhang, Baoying Chen, Michael C. Lam, Cynthia A. Tse, Garth J. S. Cooper, Karen S.L. Lam

    Published 2005
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  20. 20
    The MDM2–p53–pyruvate carboxylase signalling axis couples mitochondrial metabolism to glucose-stimulated insulin secretion in pancreatic β-cells

    The MDM2–p53–pyruvate carboxylase signalling axis couples mitochondrial metabolism to glucose-stimulated insulin secretion in pancreatic β-cells by Xiaomu Li, Kenneth K.Y. Cheng, Zhuohao Liu, Jin‐Kui Yang, Baile Wang, Xue Jiang, Yawen Zhou, Philip Hallenborg, Ruby L.C. Hoo, Karen S.L. Lam, Yasuhiro Ikeda, Xin Gao, Aimin Xu

    Published 2016
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