Resultados de procura - Rose Hurren

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  1. 1
    Activated, But Not Resting, T Cells Can Be Recognized and Killed by Syngeneic NK Cells

    Activated, But Not Resting, T Cells Can Be Recognized and Killed by Syngeneic NK Cells por Brian Rabinovich, Jennifer Li, John P. Shannon, Rose Hurren, Jan Chalupny, David Cosman, Richard G. Miller

    Publicado 2003
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  2. 2
    A Novel Formulation of Tigecycline Has Enhanced Stability and Sustained Antibacterial and Antileukemic Activity

    A Novel Formulation of Tigecycline Has Enhanced Stability and Sustained Antibacterial and Antileukemic Activity por Yulia Jitkova, Marcela Gronda, Rose Hurren, Xiaoming Wang, Carolyn A. Goard, Bozhena Jhas, Aaron D. Schimmer

    Publicado 2014
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  3. 3
    The proteomic landscape of genotoxic stress-induced micronuclei

    The proteomic landscape of genotoxic stress-induced micronuclei por Kate MacDonald, Shahbaz Khan, Brian Lin, Rose Hurren, Aaron D. Schimmer, Thomas Kislinger, Shane M. Harding

    Publicado 2024
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  4. 4
    A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity

    A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity por Samir H. Barghout, Ahmed Aman, Kazem Nouri, Zachary Blatman, Karen Arevalo, Geethu Emily Thomas, Neil MacLean, Rose Hurren, Troy Ketela, Mehakpreet Saini, Moustafa Abohawya, Taira Kiyota, Rima Al‐awar, Aaron D. Schimmer

    Publicado 2021
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  5. 5
    Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells

    Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells por Yanina Eberhard, Sean McDermott, Xiaoming Wang, Marcela Gronda, Amudha L. Venugopal, Tabitha E. Wood, Rose Hurren, Alessandro Datti, Robert A. Batey, Jeffrey L. Wrana, William E. Antholine, John E. Dick, Aaron D. Schimmer

    Publicado 2009
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  6. 6
    The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma

    The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma por Paul A. Spagnuolo, Jiayi Hu, Rose Hurren, Xiaoming Wang, Marcela Gronda, Mahadeo A. Sukhai, Ashley Di Meo, Jonathan Boss, Iman Ashali, Reza Beheshti Zavareh, Noah Fine, Craig D. Simpson, Sumaiya Sharmeen, Robert Rottapel, Aaron D. Schimmer

    Publicado 2010
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  7. 7
    A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia

    A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia por Gregory A. Reed, Gary J. Schiller, Suman Kambhampati, Martin S. Tallman, Dan Douer, Mark D. Minden, Karen Yee, Vikas Gupta, Joseph Brandwein, Yulia Jitkova, Marcela Gronda, Rose Hurren, Aisha Shamas‐Din, Andre C. Schuh, Aaron D. Schimmer

    Publicado 2016
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  8. 8
    Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation

    Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation por Craig D. Simpson, Imtiaz A. Mawji, Kika Anyiwe, Moyo A. Williams, Xiaoming Wang, Amudha L. Venugopal, Marcela Gronda, Rose Hurren, Sonia Cheng, Stefano Serra, Reza Beheshti Zavareh, Alessandro Datti, Jeffrey L. Wrana, Shereen Ezzat, Aaron D. Schimmer

    Publicado 2009
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  9. 9
    The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells

    The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells por Sumaiya Sharmeen, Marko Škrtić, Mahadeo A. Sukhai, Rose Hurren, Marcela Gronda, Xiaoming Wang, Sonali B. Fonseca, Hongxiang Sun, Tabitha E. Wood, Richard A. Ward, Mark D. Minden, Robert A. Batey, Alessandro Datti, Jeffrey L. Wrana, Shana O. Kelley, Aaron D. Schimmer

    Publicado 2010
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  10. 10
    The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice

    The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice por Zubin Zhang, Jiefei Tong, Xiaowen Tang, Jiaxiang Juan, Biyin Cao, Rose Hurren, Guodong Chen, Paul Taylor, Xin Xu, Chang-Xin Shi, Juan Du, Jian Hou, Guanghui Wang, Depei Wu, A. Keith Stewart, Aaron D. Schimmer, Michael F. Moran, Xinliang Mao

    Publicado 2016
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  11. 11
    Leveraging increased cytoplasmic nucleoside kinase activity to target mtDNA and oxidative phosphorylation in AML

    Leveraging increased cytoplasmic nucleoside kinase activity to target mtDNA and oxidative phosphorylation in AML por Sanduni U. Liyanage, Rose Hurren, Véronique Voisin, Gaëlle Bridon, Xiaoming Wang, Changjiang Xu, Neil MacLean, Thirushi Siriwardena, Marcela Gronda, Dana Yehudai, Shrivani Sriskanthadevan, Daina Avizonis, Aisha Shamas‐Din, Mark D. Minden, Gary D. Bader, Rebecca R. Laposa, Aaron D. Schimmer

    Publicado 2017
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  12. 12
    Venetoclax enhances T cell–mediated antileukemic activity by increasing ROS production

    Venetoclax enhances T cell–mediated antileukemic activity by increasing ROS production por Jong Bok Lee, Dilshad H. Khan, Rose Hurren, Mingjing Xu, Yoosu Na, Hyeonjeong Kang, Sara Mirali, Xiaoming Wang, Marcela Gronda, Yulia Jitkova, Neil MacLean, Andrea Arruda, Zoe Alaniz, Marina Konopleva, Michael Andreeff, Mark D. Minden, Zhang Li, Aaron D. Schimmer

    Publicado 2021
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  13. 13
    Selective Inhibition of Histone Deacetylases Sensitizes Malignant Cells to Death Receptor Ligands

    Selective Inhibition of Histone Deacetylases Sensitizes Malignant Cells to Death Receptor Ligands por Tabitha E. Wood, Shadi Dalili, Craig D. Simpson, Mahadeo A. Sukhai, Rose Hurren, Kika Anyiwe, Xinliang Mao, Fernando Suárez, Marcela Gronda, Yanina Eberhard, Neil MacLean, Troy Ketela, John C. Reed, Jason Moffat, Mark D. Minden, Robert A. Batey, Aaron D. Schimmer

    Publicado 2010
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  14. 14
    Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death

    Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death por Eric A. Lee, Leonard Angka, Sarah-Grace Rota, Thomas Hanlon, Andrew Mitchell, Rose Hurren, Xiao Ming Wang, Marcela Gronda, Ezel Boyacı, Barbara Bojko, Mark D. Minden, Shrivani Sriskanthadevan, Alessandro Datti, Jeffery L. Wrana, Andrea N. Edginton, Janusz Pawliszyn, Jamie W. Joseph, Joe Quadrilatero, Aaron D. Schimmer, Paul A. Spagnuolo

    Publicado 2015
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  15. 15
    The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma

    The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma por G. Wei Xu, Mohsin Ali, Tabitha E. Wood, Derek Wong, Neil MacLean, Xiaoming Wang, Marcela Gronda, Marko Škrtić, Xiaoming Li, Rose Hurren, Xinliang Mao, Meenakshi Venkatesan, Reza Beheshti Zavareh, Troy Ketela, John C. Reed, David R. Rose, Jason Moffat, Robert A. Batey, Sirano Dhe‐Paganon, Aaron D. Schimmer

    Publicado 2010
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  16. 16
    Wnt Inhibitor Screen Reveals Iron Dependence of β-Catenin Signaling in Cancers

    Wnt Inhibitor Screen Reveals Iron Dependence of β-Catenin Signaling in Cancers por Siyuan Song, Tania Christova, Stephen Perusini, Solmaz Alizadeh, Ren-Yue Bao, Bryan W. Miller, Rose Hurren, Yulia Jitkova, Marcela Gronda, Methvin Isaac, Babu Joseph, Ratheesh Subramaniam, Ahmed Aman, Anh Chau, Donna E. Hogge, Scott J. Weir, James M. Kasper, Aaron D. Schimmer, Rima Al‐awar, Jeffrey L. Wrana, Liliana Attisano

    Publicado 2011
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  17. 17
    Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignancies

    Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignancies por Mark D. Minden, Donna E. Hogge, Scott J. Weir, Jim Kasper, Debra Webster, Lavonne Patton, Yulia Jitkova, Rose Hurren, Marcela Gronda, Carolyn A. Goard, Lian Rajewski, John L. Haslam, Kathleen E. Heppert, Kevin Schorno, Hong Chang, Joseph Brandwein, Vikas Gupta, Andre C. Schuh, Suzanne Trudel, Karen Yee, Gregory A. Reed, Aaron D. Schimmer

    Publicado 2013
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  18. 18
    Biological and therapeutic implications of a unique subtype of NPM1 mutated AML

    Biological and therapeutic implications of a unique subtype of NPM1 mutated AML por Arvind Singh Mer, Emily Heath, Seyed Ali Madani Tonekaboni, Nergiz Doğan, Sisira Kadambat Nair, Alex Murison, Laura García‐Prat, Liran I. Shlush, Rose Hurren, Véronique Voisin, Gary D. Bader, Corey Nislow, Mattias Rantalainen, Sören Lehmann, Mark Gower, Cynthia J. Guidos, Mathieu Lupien, John E. Dick, Mark D. Minden, Aaron D. Schimmer, Benjamin Haibe‐Kains

    Publicado 2021
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  19. 19
    AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

    AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress por Shrivani Sriskanthadevan, Danny V. Jeyaraju, Timothy Chung, Swayam Prabha, Wei Xu, Marko Škrtić, Bozhena Jhas, Rose Hurren, Marcela Gronda, Xiaoming Wang, Yulia Jitkova, Mahadeo A. Sukhai, Feng-Hsu Lin, Neil MacLean, Rob C. Laister, Carolyn A. Goard, Peter Mullen, Stephanie Z. Xie, Linda Z. Penn, Ian M. Rogers, John E. Dick, Mark D. Minden, Aaron D. Schimmer

    Publicado 2015
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  20. 20
    Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal

    Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal por Rashim Pal Singh, Danny V. Jeyaraju, Véronique Voisin, Rose Hurren, Changjiang Xu, James R. Hawley, Samir H. Barghout, Dilshad H. Khan, Marcela Gronda, Xiaoming Wang, Yulia Jitkova, David Sharon, Sanduni Liyanagae, Neil MacLean, Ayesh K. Seneviratene, Sara Mirali, Adina Borenstein, Geethu Emily Thomas, Joelle Soriano, Elias Orouji, Mark D. Minden, Andrea Arruda, Steven M. Chan, Gary D. Bader, Mathieu Lupien, Aaron D. Schimmer

    Publicado 2020
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