Resultados de procura - Root, David E

Detecting Spatial Patterns in Biological Array Experiments por ROOT, DAVID E., KELLEY, BRIAN P., STOCKWELL, BRENT R.

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Global analysis of large-scale chemical and biological experiments por Root, David E, Kelley, Brian P, Stockwell, Brent R

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Synthetic lethal screening in the mammalian central nervous system identifies Gpx6 as a modulator of Huntington’s disease por Shema, Reut, Kulicke, Ruth, Cowley, Glenn S., Stein, Rachael, Root, David E., Heiman, Myriam

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High-throughput platform for identifying molecular factors involved in phenotypic stabilization of primary human hepatocytes in vitro por Shan, Jing, Logan, David J., Root, David E., Carpenter, Anne E., Bhatia, Sangeeta N.

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Mitochondrial and Nuclear Genomic Responses to Loss of LRPPRC Expression por Gohil, Vishal M., Nilsson, Roland, Belcher-Timme, Casey A., Luo, Biao, Root, David E., Mootha, Vamsi K.

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Correction: Mitochondrial and nuclear genomic responses to loss of LRPPRC expression. por Gohil, Vishal M., Nilsson, Roland, Belcher-Timme, Casey A., Luo, Biao, Root, David E., Mootha, Vamsi K.

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Conserved pathways within bacteria and yeast as revealed by global protein network alignment por Kelley, Brian P., Sharan, Roded, Karp, Richard M., Sittler, Taylor, Root, David E., Stockwell, Brent R., Ideker, Trey

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Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8(+) T-cell effector differentiation por Godec, Jernej, Cowley, Glenn S., Barnitz, R. Anthony, Alkan, Ozan, Root, David E., Sharpe, Arlene H., Haining, W. Nicholas

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Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool por Donovan, Katherine F., Hegde, Mudra, Sullender, Meagan, Vaimberg, Emma W., Johannessen, Cory M., Root, David E., Doench, John G.

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A genome-scale CRISPR screen identifies the ERBB and mTOR signalling networks as key determinants of response to PI3K inhibition in pancreatic cancer por Milton, Charlotte K., Self, Annette J., Clarke, Paul A., Banerji, Udai, Piccioni, Federica, Root, David E., Whittaker, Steven R.

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Receptor Tyrosine Kinases Fall into Distinct Classes Based on Their Inferred Signaling Networks por Wagner, Joel P., Wolf-Yadlin, Alejandro, Sevecka, Mark, Grenier, Jennifer K., Root, David E., Lauffenburger, Douglas A., MacBeath, Gavin

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Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression por Rosenbluh, Joseph, Xu, Han, Harrington, William, Gill, Stanley, Wang, Xiaoxing, Vazquez, Francisca, Root, David E., Tsherniak, Aviad, Hahn, William C.

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A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation por Arroyo, Jason D., Jourdain, Alexis A., Calvo, Sarah E., Ballarano, Carmine A., Doench, John G., Root, David E., Mootha, Vamsi K.

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Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects por Dempster, Joshua M., Boyle, Isabella, Vazquez, Francisca, Root, David E., Boehm, Jesse S., Hahn, William C., Tsherniak, Aviad, McFarland, James M.

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A Targeted RNA Interference Screen Reveals Novel Epigenetic Factors That Regulate Herpesviral Gene Expression por Oh, Hyung Suk, Bryant, Kevin F., Nieland, Thomas J. F., Mazumder, Aprotim, Bagul, Mukta, Bathe, Mark, Root, David E., Knipe, David M.

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High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons por Nieland, Thomas J. F., Logan, David J., Saulnier, Jessica, Lam, Daniel, Johnson, Caroline, Root, David E., Carpenter, Anne E., Sabatini, Bernardo L.

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Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects por Singh, Shantanu, Wu, Xiaoyun, Ljosa, Vebjorn, Bray, Mark-Anthony, Piccioni, Federica, Root, David E., Doench, John G., Boehm, Jesse S., Carpenter, Anne E.

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Aire-dependent genes undergo Clp1-mediated 3’UTR shortening associated with higher transcript stability in the thymus por Guyon, Clotilde, Jmari, Nada, Padonou, Francine, Li, Yen-Chin, Ucar, Olga, Fujikado, Noriyuki, Coulpier, Fanny, Blanchet, Christophe, Root, David E, Giraud, Matthieu

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A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition por Whittaker, Steven R., Theurillat, Jean-Philippe, Van Allen, Eliezer, Wagle, Nikhil, Hsiao, Jessica, Cowley, Glenn S., Schadendorf, Dirk, Root, David E., Garraway, Levi A.

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Targeted shRNA screening identified critical roles of pleckstrin-2 in erythropoiesis por Zhao, Baobing, Keerthivasan, Ganesan, Mei, Yang, Yang, Jing, McElherne, James, Wong, Piu, Doench, John G., Feng, Gang, Root, David E., Ji, Peng

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