Search Results - Rob Leurs

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  1. 1
    The Epstein-Barr Virus-encoded G Protein-coupled Receptor BILF1 Hetero-oligomerizes with Human CXCR4, Scavenges Gαi Proteins, and Constitutively Impairs CXCR4 Functioning

    The Epstein-Barr Virus-encoded G Protein-coupled Receptor BILF1 Hetero-oligomerizes with Human CXCR4, Scavenges Gαi Proteins, and Constitutively Impairs CXCR4 Functioning by Saskia Nijmeijer, Rob Leurs, Martine J. Smit, Henry F. Vischer

    Published 2010
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  2. 2
    Pharmacological characterization of seven human histamine H3 receptor isoforms

    Pharmacological characterization of seven human histamine H3 receptor isoforms by Meichun Gao, Mabel E. Dekker, Rob Leurs, Henry F. Vischer

    Published 2024
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  3. 3
    Recent Developments in the Optical Control of Adrenergic Signaling

    Recent Developments in the Optical Control of Adrenergic Signaling by Shuang Shi, Y. Cao, Maikel Wijtmans, Henry F. Vischer, Rob Leurs

    Published 2025
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  4. 4
    Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors

    Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors by Sabrina M. de Munnik, Martine J. Smit, Rob Leurs, Henry F. Vischer

    Published 2015
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  5. 5
    Pharmacological characterization of the human histamine H<sub>2</sub> receptor stably expressed in Chinese hamster ovary cells

    Pharmacological characterization of the human histamine H<sub>2</sub> receptor stably expressed in Chinese hamster ovary cells by Rob Leurs, Martine J. Smit, Wiro M.B.P. Menge, H. Timmerman

    Published 1994
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  6. 6
    The histamine H3 receptor: from gene cloning to H3 receptor drugs

    The histamine H3 receptor: from gene cloning to H3 receptor drugs by Rob Leurs, Remko A. Bakker, Henk Timmerman, Iwan J. P. de Esch

    Published 2005
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  7. 7
    Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study

    Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study by Albert J. Kooistra, Rob Leurs, Iwan J. P. de Esch, Chris de Graaf

    Published 2015
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  8. 8
    Kaposi's Sarcoma-Associated Herpesvirus-Encoded G Protein-Coupled Receptor ORF74 Constitutively Activates p44/p42 MAPK and Akt via G<sub>i</sub>and Phospholipase C-Dependent Signaling Pathways

    Kaposi's Sarcoma-Associated Herpesvirus-Encoded G Protein-Coupled Receptor ORF74 Constitutively Activates p44/p42 MAPK and Akt via G<sub>i</sub>and Phospholipase C-Dependent Signal... by Martine J. Smit, Dennis Verzijl, Paola Casarosa, Marjon Navis, Henk Timmerman, Rob Leurs

    Published 2002
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  9. 9
    Expression of a cloned rat histamine H2 receptor mediating inhibition of arachidonate release and activation of cAMP accumulation.

    Expression of a cloned rat histamine H2 receptor mediating inhibition of arachidonate release and activation of cAMP accumulation. by Élisabeth Traiffort, Martial Ruat, J.M. Arrang, Rob Leurs, Daniele Piomelli, Jean-Charles Schwartz

    Published 1992
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  10. 10
    Mutational Analysis of the Antagonist-binding Site of the Histamine H1 Receptor

    Mutational Analysis of the Antagonist-binding Site of the Histamine H1 Receptor by Kerstin Wieland, Antonius ter Laak, Martine J. Smit, Ronald Kühne, Henk Timmerman, Rob Leurs

    Published 1999
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  11. 11
    Ligand Residence Time at G-protein–Coupled Receptors—Why We Should Take Our Time To Study It

    Ligand Residence Time at G-protein–Coupled Receptors—Why We Should Take Our Time To Study It by Carsten Hoffmann, Marián Castro, Ago Rinken, Rob Leurs, Stephen J. Hill, Henry F. Vischer

    Published 2015
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  12. 12
    The clinical pharmacology of non-sedating antihistamines

    The clinical pharmacology of non-sedating antihistamines by Kazuhiko Yanai, Takeo Yoshikawa, Ai Yanai, Tadaho Nakamura, Tomomitsu Iida, Rob Leurs, Manabu Tashiro

    Published 2017
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  13. 13
    Short- and Long-Term Social Recognition Memory Are Differentially Modulated by Neuronal Histamine

    Short- and Long-Term Social Recognition Memory Are Differentially Modulated by Neuronal Histamine by Barbara Rani, Bruna Silva-Marques, Rob Leurs, Maria Beatrice Passani, Patrizio Blandina, Gustavo Provensi

    Published 2021
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  14. 14
    A structural chemogenomics analysis of aminergic <scp>GPCRs</scp>: lessons for histamine receptor ligand design

    A structural chemogenomics analysis of aminergic <scp>GPCRs</scp>: lessons for histamine receptor ligand design by Albert J. Kooistra, Sebastiaan Kuhne, Iwan J. P. de Esch, Rob Leurs, Chris de Graaf

    Published 2013
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  15. 15
    Molecular and biochemical pharmacology of the histamine H<sub>4</sub> receptor

    Molecular and biochemical pharmacology of the histamine H<sub>4</sub> receptor by Rob Leurs, Paul L. Chazot, Fiona C. Shenton, Herman D. Lim, Iwan J. P. de Esch

    Published 2009
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  16. 16
    Human Inflammatory Dendritic Epidermal Cells Express a Functional Histamine H4 Receptor

    Human Inflammatory Dendritic Epidermal Cells Express a Functional Histamine H4 Receptor by Dorothea Dijkstra, Holger Stark, Paul L. Chazot, Fiona C. Shenton, Rob Leurs, Thomas Werfel, Ralf Gutzmer

    Published 2008
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  17. 17
    Constitutive Signaling of the Human Cytomegalovirus-encoded Chemokine Receptor US28

    Constitutive Signaling of the Human Cytomegalovirus-encoded Chemokine Receptor US28 by Paola Casarosa, Remko A. Bakker, Dennis Verzijl, Marjon Navis, Henk Timmerman, Rob Leurs, Martine J. Smit

    Published 2001
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  18. 18
    Inhibition of cortical acetylcholine release and cognitive performance by histamine H<sub>3</sub> receptor activation in rats

    Inhibition of cortical acetylcholine release and cognitive performance by histamine H<sub>3</sub> receptor activation in rats by Patrizio Blandina, Marco Giorgetti, L. Bartolini, Marco Cecchi, H. Timmerman, Rob Leurs, Giancarlo Pepeu, Maria Grazia Giovannini

    Published 1996
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  19. 19
    Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.

    Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation. by Martial Ruat, Élisabeth Traiffort, Rob Leurs, J. Tardivel‐Lacombe, Jorge Díaz, J.M. Arrang, Jean-Charles Schwartz

    Published 1993
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  20. 20
    Pharmacogenomic and Structural Analysis of Constitutive G Protein–Coupled Receptor Activity

    Pharmacogenomic and Structural Analysis of Constitutive G Protein–Coupled Receptor Activity by Martine J. Smit, Henry F. Vischer, Remko A. Bakker, Aldo Jongejan, Henk Timmerman, Leonardo Pardo, Rob Leurs

    Published 2006
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