Resultats de la cerca - Rina Nishii

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  1. 1
    The NUDIX hydrolase NUDT5 regulates thiopurine metabolism and cytotoxicity

    The NUDIX hydrolase NUDT5 regulates thiopurine metabolism and cytotoxicity per Maud Maillard, Rina Nishii, Hieu Vu, Kashi Raj Bhattarai, Wenjian Yang, Jing Li, Ute Hofmann, Daniel Savic, Smita Bhatia, Matthias Schwab, Min Ni, Jun J. Yang

    Publicat 2025
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  2. 2
    The effects of inherited NUDT15 polymorphisms on thiopurine active metabolites in Japanese children with acute lymphoblastic leukemia

    The effects of inherited NUDT15 polymorphisms on thiopurine active metabolites in Japanese children with acute lymphoblastic leukemia per Takaya Moriyama, Rina Nishii, Ting-Nien Lin, Kentaro Kihira, Hidemi Toyoda, Jacob Nersting, Motohiro Kato, Katsuyoshi Koh, Hiroto Inaba, Atsushi Manabe, Kjeld Schmiegelow, Jun J. Yang, Hiroki Hori

    Publicat 2017
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  3. 3
    Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry

    Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry per Takaya Moriyama, Yung‐Li Yang, Rina Nishii, Hany Ariffin, Chengcheng Liu, Ting-Nien Lin, Wenjian Yang, Dong‐Tsamn Lin, Chih‐Hsiang Yu, Shirley Kow Yin Kham, Ching‐Hon Pui, William E. Evans, Sima Jeha, Mary V. Relling, Allen Eng Juh Yeoh, Jun J. Yang

    Publicat 2017
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  4. 4
    Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy

    Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy per Rina Nishii, Takaya Moriyama, Laura J. Janke, Wenjian Yang, Chase C. Suiter, Ting-Nien Lin, Lie Li, Kentaro Kihira, Hidemi Toyoda, Ute Hofmann, Matthias Schwab, Masatoshi Takagi, Tomohiro Morio, Atsushi Manabe, Shirley Kow Yin Kham, Nan Jiang, Karen R. Rabin, Motohiro Kato, Katsuyoshi Koh, Allen Eng Juh Yeoh, Hiroki Hori, Jun J. Yang

    Publicat 2018
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  5. 5
    Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor

    Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor per Masatoshi Takagi, Misa Yoshida, Yoshino Nemoto, Hiroyuki Tamaichi, Rika Tsuchida, Masafumi Seki, Kumiko Uryu, N. Hoshino, Rina Nishii, Satoshi Miyamoto, Masahiro Saito, Toshiaki Shimizu, Ryoji Hanada, Hideo Kaneko, Toshiyuki Fukao, Takatoshi Koyama, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Yusuke Sato, Yoichi Fujii, Keisuke Kataoka, Yusuke Okuno, Kenichi Yoshida, Tomohiro Morio, Akira Oka, Miki Ohira, Yasuhide Hayashi, Akira Nakagawara, Seishi Ogawa, Shuki Mizutani, Junko Takita

    Publicat 2017
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  6. 6
    Molecular basis of <i>ETV6</i>-mediated predisposition to childhood acute lymphoblastic leukemia

    Molecular basis of <i>ETV6</i>-mediated predisposition to childhood acute lymphoblastic leukemia per Rina Nishii, Rebekah Baskin-Doerfler, Wentao Yang, Ninad Oak, Xujie Zhao, Wenjian Yang, Keito Hoshitsuki, Mackenzie Bloom, Katherine Verbist, Melissa Burns, Zhenhua Li, Ting-Nien Lin, Maoxiang Qian, Takaya Moriyama, Julie M. Gastier‐Foster, Karen R. Rabin, Elizabeth A. Raetz, Charles G. Mullighan, Ching‐Hon Pui, Allen Eng Juh Yeoh, Jinghui Zhang, Monika L. Metzger, Jeffery M. Klco, Stephen P. Hunger, Scott Newman, Gang Wu, Mignon L. Loh, Kim E. Nichols, Jun J. Yang

    Publicat 2020
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  7. 7
    Lisocabtagene maraleucel in follicular lymphoma: the phase 2 TRANSCEND FL study

    Lisocabtagene maraleucel in follicular lymphoma: the phase 2 TRANSCEND FL study per Franck Morschhauser, Saurabh Dahiya, M. Lia Palomba, Alejandro Martı́n, Juan Luis Reguera Ortega, John Kuruvilla, Ulrich Jäger, Guillaume Cartron, Koji Izutsu, Martin Dreyling, Brad S. Kahl, Hervé Ghesquières, Kirit M. Ardeshna, Hideki Goto, Anna Maria Barbui, Jeremy S. Abramson, Peter Borchmann, Isabelle Fleury, Stephan Mielke, Alan P Skarbnik, Sven de Vos, Manali Kamdar, Reem Karmali, Andreas Viardot, Thalia A. Farazi, Omotayo Fasan, James Lymp, Min Vedal, Rina Nishii, Ariel Avilion, Jessica Papuga, Jinender Kumar, Loretta J. Nastoupil

    Publicat 2024
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  8. 8
    Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study

    Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study per Takaya Moriyama, Monika L. Metzger, Gang Wu, Rina Nishii, Maoxiang Qian, Meenakshi Devidas, Wenjian Yang, Cheng Cheng, Xueyuan Cao, Emily A. Quinn, Susana C. Raimondi, Julie M. Gastier‐Foster, Elizabeth A. Raetz, Eric Larsen, Paul L. Martin, W. Paul Bowman, Naomi J. Winick, Yoshihiro Komada, Shuoguo Wang, Michael N. Edmonson, Heng Xu, Elaine R. Mardis, Robert S. Fulton, Ching‐Hon Pui, Charles G. Mullighan, William E. Evans, Jinghui Zhang, Stephen P. Hunger, Mary V. Relling, Kim E. Nichols, Mignon L. Loh, Jun J. Yang

    Publicat 2015
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  9. 9
    NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity

    NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity per Takaya Moriyama, Rina Nishii, Virginia Pérez-Andreu, Wenjian Yang, Federico Antillón‐Klussmann, Xujie Zhao, Ting-Nien Lin, Keito Hoshitsuki, Jacob Nersting, Kentaro Kihira, Ute Hofmann, Yoshihiro Komada, Motohiro Kato, J. Robert McCorkle, Lie Li, Katsuyoshi Koh, Cesar Najera, Shirley Kow‐Yin Kham, Tomoya Isobe, Zhiwei Chen, Edwynn Kean-Hui Chiew, Deepa Bhojwani, Cynthia Jeffries, Yan Lu, Matthias Schwab, Hiroto Inaba, Ching‐Hon Pui, Mary V. Relling, Atsushi Manabe, Hiroki Hori, Kjeld Schmiegelow, Allen Eng Juh Yeoh, William E. Evans, Jun J. Yang

    Publicat 2016
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  10. 10
    Massively parallel variant characterization identifies<i>NUDT15</i>alleles associated with thiopurine toxicity

    Massively parallel variant characterization identifies<i>NUDT15</i>alleles associated with thiopurine toxicity per Chase C. Suiter, Takaya Moriyama, Kenneth A. Matreyek, Wentao Yang, Emma Rose Scaletti, Rina Nishii, Wenjian Yang, Keito Hoshitsuki, Minu Singh, Amita Trehan, Christopher R. Parish, Colton Smith, Lie Li, Deepa Bhojwani, Liz Y. P. Yuen, Chi Kong Li, Chak-Ho Li, Yung‐Li Yang, G Walker, James Goodhand, Nicholas A. Kennedy, Federico Antillón‐Klussmann, Smita Bhatia, Mary V. Relling, Motohiro Kato, Hiroki Hori, Prateek Bhatia, Tariq Ahmad, Allen Eng Juh Yeoh, Pål Stenmark, Douglas M. Fowler, Jun J. Yang

    Publicat 2020
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