Suchergebnisse - Richard T. Eastman
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Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria von Richard T. Eastman, David A. Fidock
Veröffentlicht 2009Revisão -
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Drug‐resistant malaria: Molecular mechanisms and implications for public health von Ines Petersen, Richard T. Eastman, Michael Lanzer
Veröffentlicht 2011Revisão -
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Recent highlights in antimalarial drug resistance and chemotherapy research von David A. Fidock, Richard T. Eastman, Stephen A. Ward, Steven R. Meshnick
Veröffentlicht 2008Revisão -
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Screening the Pathogen Box for Molecules Active against Plasmodium Sexual Stages Using a New Nanoluciferase-Based Transgenic Line of P. berghei Identifies Transmission-Blocking Com... von Juliana Calit, Irina Dobrescu, Xiomara A. Gaitán, Miriam H. Borges, Marisé Solórzano Ramos, Richard T. Eastman, Daniel Y. Bargieri
Veröffentlicht 2018Artigo -
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Genome‐wide profiling of chromosome interactions in <i><scp>P</scp>lasmodium falciparum</i> characterizes nuclear architecture and reconfigurations associated with antigenic variat... von Jacob E. Lemieux, Sue Kyes, Thomas D. Otto, Avi Feller, Richard T. Eastman, Robert Pinches, Matthew Berriman, Xin‐zhuan Su, Chris Newbold
Veröffentlicht 2013Artigo -
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Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 von Tesia Bobrowski, Lu Chen, Richard T. Eastman, Zina Itkin, Paul Shinn, Catherine Z. Chen, Hui Guo, Wei Zheng, Sam Michael, Anton Simeonov, Matthew D. Hall, Alexey Zakharov, Eugene Muratov
Veröffentlicht 2020Artigo -
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Quantitative assessment of <i>Plasmodium falciparum</i> sexual development reveals potent transmission-blocking activity by methylene blue von Sophie Adjalley, Geoffrey L. Johnston, Tao Li, Richard T. Eastman, Eric H. Ekland, Abraham G. Eappen, Adam Richman, B. Kim Lee Sim, Lee M, Stephen L. Hoffman, David A. Fidock
Veröffentlicht 2011Artigo -
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Novel Transmission-Blocking Antimalarials Identified by High-Throughput Screening of Plasmodium berghei Ookluc von Juliana Calit, Jéssica E. Araújo, Bingbing Deng, Kazutoyo Miura, Xiomara A. Gaitán, Maísa da Silva Araújo, Jansen Fernandes Medeiros, Carole A. Long, Anton Simeonov, Richard T. Eastman, Daniel Y. Bargieri
Veröffentlicht 2023Artigo -
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Resistance to a Protein Farnesyltransferase Inhibitor in Plasmodium falciparum von Richard T. Eastman, John White, Oliver Hucke, Kevin D. Bauer, Kohei Yokoyama, Laxman Nallan, Debopam Chakrabarti, Christophe L. M. J. Verlinde, Michael H. Gelb, Pradipsinh K. Rathod, Wesley C. Van Voorhis
Veröffentlicht 2005Artigo -
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Supergenomic Network Compression and the Discovery of EXP1 as a Glutathione Transferase Inhibited by Artesunate von Andreas Martin Lisewski, Joel Patrick Quiros, Caroline L. Ng, Anbu Karani Adikesavan, Kazutoyo Miura, Nagireddy Putluri, Richard T. Eastman, Daniel Scanfeld, Sam Regenbogen, Lindsey M. Altenhofen, Manuel Llinás, Arun Sreekumar, Carole A. Long, David A. Fidock, Olivier Lichtarge
Veröffentlicht 2014Artigo -
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A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation von Kimberly F. Breglio, Roberto Amato, Richard T. Eastman, Pharath Lim, Juliana M. Sá, Rajarshi Guha, Sundar Ganesan, David W. Dorward, Carleen Klumpp‐Thomas, Crystal McKnight, Rick M. Fairhurst, David J. Roberts, Craig J. Thomas, Anna Katharina Simon
Veröffentlicht 2018Artigo -
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Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors von Rachel P. M. Abrams, Adam Yasgar, T Teramoto, Myoung‐Hwa Lee, Dorjbal Dorjsuren, Richard T. Eastman, Nasir Malik, Alexey Zakharov, Wenxue Li, Muzna Bachani, Kyle R. Brimacombe, Joseph P. Steiner, Matthew D. Hall, Anuradha Balasubramanian, Ajit Jadhav, Radhakrishnan Padmanabhan, Anton Simeonov, Avindra Nath
Veröffentlicht 2020Artigo -
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Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2 von Catherine Z. Chen, Paul Shinn, Zina Itkin, Richard T. Eastman, Robert Bostwick, Lynn Rasmussen, Ruili Huang, Min Shen, Xin Hu, Kelli M. Wilson, Brianna M. Brooks, Hui Guo, Tongan Zhao, Carleen Klump-Thomas, Anton Simeonov, Sam Michael, Donald C. Lo, Matthew D. Hall, Wei Zheng
Veröffentlicht 2021Artigo -
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High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations von Bryan T. Mott, Richard T. Eastman, Rajarshi Guha, Katy S. Sherlach, Amila Siriwardana, Paul Shinn, Crystal McKnight, Sam Michael, Norinne Lacerda‐Queiroz, Paresma Patel, Pwint Khine, Hongmao Sun, Monica Kasbekar, Nima Aghdam, Shaun D. Fontaine, Dongbo Liu, Tim Mierzwa, Lesley Mathews-Griner, Marc Ferrer, Adam R. Renslo, James Inglese, Jing Yuan, Paul D. Roepe, Xin‐zhuan Su, Craig J. Thomas
Veröffentlicht 2015Artigo -
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A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation von Kayode K. Ojo, Richard T. Eastman, Ramasubbarao Vidadala, Zhongsheng Zhang, Kasey Rivas, Ryan Choi, Justin D. Lutz, Molly C. Reid, Anna M. W. Fox, Matthew A. Hulverson, Mark Kennedy, Nina Isoherranen, Laura M. Kim, Kenneth M. Comess, Dale J. Kempf, Christophe L. M. J. Verlinde, Xin‐zhuan Su, Stefan H. I. Kappe, Dustin J. Maly, Erkang Fan, Wesley C. Van Voorhis
Veröffentlicht 2013Artigo -
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An OpenData portal to share COVID-19 drug repurposing data in real time von Kyle R. Brimacombe, Tongan Zhao, Richard T. Eastman, Xin Hu, Ke Wang, Mark Backus, Bolormaa Baljinnyam, Catherine Z. Chen, Lu Chen, Tara Eicher, Marc Ferrer, Ying Fu, Kirill Gorshkov, Hui Guo, Quinlin Hanson, Zina Itkin, Stephen C. Kales, Carleen Klumpp‐Thomas, Emily M. Lee, Sam Michael, Tim Mierzwa, Andrew Patt, Manisha Pradhan, Alex Renn, Paul Shinn, Jonathan H. Shrimp, Amit Viraktamath, Kelli M. Wilson, Miao Xu, Alexey Zakharov, Wei Zhu, Wei Zheng, Anton Simeonov, Ewy A. Mathé, Donald C. Lo, Matthew D. Hall, Min Shen
Veröffentlicht 2020Pré-impressão
Suchwerkzeuge:
Ähnliche Schlagworte
Biology
Immunology
Malaria
Plasmodium falciparum
Virology
Medicine
Pharmacology
Artemisinin
Computer science
Genetics
Computational biology
Drug resistance
Biochemistry
Chloroquine
Drug
Drug discovery
Gene
Bioinformatics
Parasite hosting
World Wide Web
Coronavirus disease 2019 (COVID-19)
Disease
Drug development
Enzyme
Gametocyte
Infectious disease (medical specialty)
Microbiology
Chemistry
Drug repositioning
Ecology