Resultats de la cerca - Richard T. Eastman

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  1. 1
    Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria

    Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria per Richard T. Eastman, David A. Fidock

    Publicat 2009
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  2. 2
    Drug‐resistant malaria: Molecular mechanisms and implications for public health

    Drug‐resistant malaria: Molecular mechanisms and implications for public health per Ines Petersen, Richard T. Eastman, Michael Lanzer

    Publicat 2011
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  3. 3
    Recent highlights in antimalarial drug resistance and chemotherapy research

    Recent highlights in antimalarial drug resistance and chemotherapy research per David A. Fidock, Richard T. Eastman, Stephen A. Ward, Steven R. Meshnick

    Publicat 2008
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  4. 4
    Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured <i>Plasmodium falciparum</i> Parasites

    Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured <i>Plasmodium falciparum</i> Parasites per Richard T. Eastman, Neekesh V. Dharia, Elizabeth A. Winzeler, David A. Fidock

    Publicat 2011
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  5. 5
    Thematic review series: Lipid Posttranslational Modifications. Fighting parasitic disease by blocking protein farnesylation

    Thematic review series: Lipid Posttranslational Modifications. Fighting parasitic disease by blocking protein farnesylation per Richard T. Eastman, Frederick S. Buckner, Kohei Yokoyama, Michael H. Gelb, Wesley C. Van Voorhis

    Publicat 2005
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  6. 6
    <i>Trypanosoma cruzi</i>Inactivation in Human Platelet Concentrates and Plasma by a Psoralen (Amotosalen HCl) and Long-Wavelength UV

    <i>Trypanosoma cruzi</i>Inactivation in Human Platelet Concentrates and Plasma by a Psoralen (Amotosalen HCl) and Long-Wavelength UV per Wesley C. Van Voorhis, Lynn K. Barrett, Richard T. Eastman, Ryan Alfonso, Kent Dupuis

    Publicat 2003
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  7. 7
    Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19

    Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19 per Richard T. Eastman, Jacob S. Roth, Kyle R. Brimacombe, Anton Simeonov, Min Shen, Samarjit Patnaik, Matthew D. Hall

    Publicat 2020
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  8. 8
    Screening the Pathogen Box for Molecules Active against Plasmodium Sexual Stages Using a New Nanoluciferase-Based Transgenic Line of P. berghei Identifies Transmission-Blocking Compounds

    Screening the Pathogen Box for Molecules Active against Plasmodium Sexual Stages Using a New Nanoluciferase-Based Transgenic Line of P. berghei Identifies Transmission-Blocking Com... per Juliana Calit, Irina Dobrescu, Xiomara A. Gaitán, Miriam H. Borges, Marisé Solórzano Ramos, Richard T. Eastman, Daniel Y. Bargieri

    Publicat 2018
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  9. 9
    Genome‐wide profiling of chromosome interactions in <i><scp>P</scp>lasmodium falciparum</i> characterizes nuclear architecture and reconfigurations associated with antigenic variation

    Genome‐wide profiling of chromosome interactions in <i><scp>P</scp>lasmodium falciparum</i> characterizes nuclear architecture and reconfigurations associated with antigenic variat... per Jacob E. Lemieux, Sue Kyes, Thomas D. Otto, Avi Feller, Richard T. Eastman, Robert Pinches, Matthew Berriman, Xin‐zhuan Su, Chris Newbold

    Publicat 2013
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  10. 10
    Synergistic and Antagonistic Drug Combinations against SARS-CoV-2

    Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 per Tesia Bobrowski, Lu Chen, Richard T. Eastman, Zina Itkin, Paul Shinn, Catherine Z. Chen, Hui Guo, Wei Zheng, Sam Michael, Anton Simeonov, Matthew D. Hall, Alexey Zakharov, Eugene Muratov

    Publicat 2020
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  11. 11
    Quantitative assessment of <i>Plasmodium falciparum</i> sexual development reveals potent transmission-blocking activity by methylene blue

    Quantitative assessment of <i>Plasmodium falciparum</i> sexual development reveals potent transmission-blocking activity by methylene blue per Sophie Adjalley, Geoffrey L. Johnston, Tao Li, Richard T. Eastman, Eric H. Ekland, Abraham G. Eappen, Adam Richman, B. Kim Lee Sim, Lee M, Stephen L. Hoffman, David A. Fidock

    Publicat 2011
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  12. 12
    Novel Transmission-Blocking Antimalarials Identified by High-Throughput Screening of Plasmodium berghei Ookluc

    Novel Transmission-Blocking Antimalarials Identified by High-Throughput Screening of Plasmodium berghei Ookluc per Juliana Calit, Jéssica E. Araújo, Bingbing Deng, Kazutoyo Miura, Xiomara A. Gaitán, Maísa da Silva Araújo, Jansen Fernandes Medeiros, Carole A. Long, Anton Simeonov, Richard T. Eastman, Daniel Y. Bargieri

    Publicat 2023
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  13. 13
    Resistance to a Protein Farnesyltransferase Inhibitor in Plasmodium falciparum

    Resistance to a Protein Farnesyltransferase Inhibitor in Plasmodium falciparum per Richard T. Eastman, John White, Oliver Hucke, Kevin D. Bauer, Kohei Yokoyama, Laxman Nallan, Debopam Chakrabarti, Christophe L. M. J. Verlinde, Michael H. Gelb, Pradipsinh K. Rathod, Wesley C. Van Voorhis

    Publicat 2005
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  14. 14
    Supergenomic Network Compression and the Discovery of EXP1 as a Glutathione Transferase Inhibited by Artesunate

    Supergenomic Network Compression and the Discovery of EXP1 as a Glutathione Transferase Inhibited by Artesunate per Andreas Martin Lisewski, Joel Patrick Quiros, Caroline L. Ng, Anbu Karani Adikesavan, Kazutoyo Miura, Nagireddy Putluri, Richard T. Eastman, Daniel Scanfeld, Sam Regenbogen, Lindsey M. Altenhofen, Manuel Llinás, Arun Sreekumar, Carole A. Long, David A. Fidock, Olivier Lichtarge

    Publicat 2014
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  15. 15
    A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

    A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation per Kimberly F. Breglio, Roberto Amato, Richard T. Eastman, Pharath Lim, Juliana M. Sá, Rajarshi Guha, Sundar Ganesan, David W. Dorward, Carleen Klumpp‐Thomas, Crystal McKnight, Rick M. Fairhurst, David J. Roberts, Craig J. Thomas, Anna Katharina Simon

    Publicat 2018
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  16. 16
    Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

    Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors per Rachel P. M. Abrams, Adam Yasgar, T Teramoto, Myoung‐Hwa Lee, Dorjbal Dorjsuren, Richard T. Eastman, Nasir Malik, Alexey Zakharov, Wenxue Li, Muzna Bachani, Kyle R. Brimacombe, Joseph P. Steiner, Matthew D. Hall, Anuradha Balasubramanian, Ajit Jadhav, Radhakrishnan Padmanabhan, Anton Simeonov, Avindra Nath

    Publicat 2020
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  17. 17
    Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

    Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2 per Catherine Z. Chen, Paul Shinn, Zina Itkin, Richard T. Eastman, Robert Bostwick, Lynn Rasmussen, Ruili Huang, Min Shen, Xin Hu, Kelli M. Wilson, Brianna M. Brooks, Hui Guo, Tongan Zhao, Carleen Klump-Thomas, Anton Simeonov, Sam Michael, Donald C. Lo, Matthew D. Hall, Wei Zheng

    Publicat 2021
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  18. 18
    High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations

    High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations per Bryan T. Mott, Richard T. Eastman, Rajarshi Guha, Katy S. Sherlach, Amila Siriwardana, Paul Shinn, Crystal McKnight, Sam Michael, Norinne Lacerda‐Queiroz, Paresma Patel, Pwint Khine, Hongmao Sun, Monica Kasbekar, Nima Aghdam, Shaun D. Fontaine, Dongbo Liu, Tim Mierzwa, Lesley Mathews-Griner, Marc Ferrer, Adam R. Renslo, James Inglese, Jing Yuan, Paul D. Roepe, Xin‐zhuan Su, Craig J. Thomas

    Publicat 2015
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  19. 19
    A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation

    A Specific Inhibitor of PfCDPK4 Blocks Malaria Transmission: Chemical-genetic Validation per Kayode K. Ojo, Richard T. Eastman, Ramasubbarao Vidadala, Zhongsheng Zhang, Kasey Rivas, Ryan Choi, Justin D. Lutz, Molly C. Reid, Anna M. W. Fox, Matthew A. Hulverson, Mark Kennedy, Nina Isoherranen, Laura M. Kim, Kenneth M. Comess, Dale J. Kempf, Christophe L. M. J. Verlinde, Xin‐zhuan Su, Stefan H. I. Kappe, Dustin J. Maly, Erkang Fan, Wesley C. Van Voorhis

    Publicat 2013
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  20. 20
    An OpenData portal to share COVID-19 drug repurposing data in real time

    An OpenData portal to share COVID-19 drug repurposing data in real time per Kyle R. Brimacombe, Tongan Zhao, Richard T. Eastman, Xin Hu, Ke Wang, Mark Backus, Bolormaa Baljinnyam, Catherine Z. Chen, Lu Chen, Tara Eicher, Marc Ferrer, Ying Fu, Kirill Gorshkov, Hui Guo, Quinlin Hanson, Zina Itkin, Stephen C. Kales, Carleen Klumpp‐Thomas, Emily M. Lee, Sam Michael, Tim Mierzwa, Andrew Patt, Manisha Pradhan, Alex Renn, Paul Shinn, Jonathan H. Shrimp, Amit Viraktamath, Kelli M. Wilson, Miao Xu, Alexey Zakharov, Wei Zhu, Wei Zheng, Anton Simeonov, Ewy A. Mathé, Donald C. Lo, Matthew D. Hall, Min Shen

    Publicat 2020
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