Search Results - Richard Possemato

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  1. 1
    Amino acid management in cancer

    Amino acid management in cancer by Zhi-Yang Tsun, Richard Possemato

    Published 2015
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  2. 2
    RETRACTED: Cancer-Associated PP2A Aα Subunits Induce Functional Haploinsufficiency and Tumorigenicity

    RETRACTED: Cancer-Associated PP2A Aα Subunits Induce Functional Haploinsufficiency and Tumorigenicity by Wen Chen, Jason D. Arroyo, Jamie C. Timmons, Richard Possemato, William C. Hahn

    Published 2005
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  3. 3
    T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells

    T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells by Geanncarlo Lugo‐Villarino, Roberto Maldonado-López, Richard Possemato, Cristina Peñaranda, Laurie H. Glimcher

    Published 2003
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  4. 4
    Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5

    Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5 by Erdem M. Terzi, Vladislav O. Sviderskiy, Samantha Alvarez, Gabrielle C. Whiten, Richard Possemato

    Published 2021
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  5. 5
    Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening

    Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening by Anne M. Strohecker, Sonia Joshi, Richard Possemato, Robert T. Abraham, David M. Sabatini, Eileen White

    Published 2015
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  6. 6
    Nek4 Regulates Entry into Replicative Senescence and the Response to DNA Damage in Human Fibroblasts

    Nek4 Regulates Entry into Replicative Senescence and the Response to DNA Damage in Human Fibroblasts by Christine Nguyen, Richard Possemato, Erica L. Bauerlein, Anyong Xie, Ralph Scully, William C. Hahn

    Published 2012
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  7. 7
    Identification of specific PP2A complexes involved in human cell transformation

    Identification of specific PP2A complexes involved in human cell transformation by Wen Chen, Richard Possemato, Katrina Campbell, Courtney A. Plattner, David C. Pallas, William C. Hahn

    Published 2004
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  8. 8
    Allosteric regulation of CAD modulates de novo pyrimidine synthesis during the cell cycle

    Allosteric regulation of CAD modulates de novo pyrimidine synthesis during the cell cycle by Jong Shin, Hannan Mir, Maaz A. Khurram, Kenji M. Fujihara, Brian David Dynlacht, Timothy Cardozo, Richard Possemato

    Published 2023
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  9. 9
    An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

    An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA by Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, Vivi Kasim, Yoshihide Hayashizaki, William C. Hahn, Kenkichi Masutomi

    Published 2009
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  10. 10
    A Diverse Array of Cancer-Associated <i>MTOR</i> Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity

    A Diverse Array of Cancer-Associated <i>MTOR</i> Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity by Brian C. Grabiner, Valentina Nardi, Kıvanç Birsoy, Richard Possemato, Kuang Shen, Sumi Sinha, Alexander C. Jordan, Andrew H. Beck, David M. Sabatini

    Published 2014
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  11. 11
    NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis

    NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis by Samantha Alvarez, Vladislav O. Sviderskiy, Erdem M. Terzi, Thales Papagiannakopoulos, André L. Moreira, Sylvia Adams, David M. Sabatini, Kıvanç Birsoy, Richard Possemato

    Published 2017
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  12. 12
    Maintenance of tumor initiating cells of defined genetic composition by nucleostemin

    Maintenance of tumor initiating cells of defined genetic composition by nucleostemin by Naoko Okamoto, Mami Yasukawa, Christine Nguyen, Vivi Kasim, Yoshiko Maida, Richard Possemato, Tatsuhiro Shibata, Keith L. Ligon, Kiyoko Fukami, William C. Hahn, Kenkichi Masutomi

    Published 2011
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  13. 13
    The telomerase reverse transcriptase regulates chromatin state and DNA damage responses

    The telomerase reverse transcriptase regulates chromatin state and DNA damage responses by Kenkichi Masutomi, Richard Possemato, Judy M.Y. Wong, Jennifer L. Currier, Zuzana Tóthová, Judith Manola, Shridar Ganesan, Peter M. Lansdorp, Kathleen Collins, William C. Hahn

    Published 2005
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  14. 14
    Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

    Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides by Kıvanç Birsoy, Richard Possemato, Franziska K. Lorbeer, Erol C. Bayraktar, Prathapan Thiru, Burcu Yücel, Timothy C. Wang, Walter W. Chen, Clary B. Clish, David M. Sabatini

    Published 2014
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  15. 15
    Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs

    Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs by Denise R. Minton, Minwoo Nam, Daniel J. McLaughlin, Jong Shin, Erol C. Bayraktar, Samantha Alvarez, Vladislav O. Sviderskiy, Thales Papagiannakopoulos, David M. Sabatini, Kıvanç Birsoy, Richard Possemato

    Published 2018
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  16. 16
    Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours

    Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours by Javier García‐Bermúdez, Lou Baudrier, Konnor La, Xiphias Ge Zhu, Justine Fidelin, Vladislav O. Sviderskiy, Thales Papagiannakopoulos, Henrik Molina, Matija Snuderl, Caroline A. Lewis, Richard Possemato, Kıvanç Birsoy

    Published 2018
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  17. 17
    Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming

    Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming by Martin Vaeth, Máté Maus, Stefan Klein-Heßling, Elizaveta Freinkman, Jun J. Yang, Miriam Eckstein, Scott B. Cameron, Stuart E. Turvey, Edgar Serfling, Friederike Berberich‐Siebelt, Richard Possemato, Stefan Feske

    Published 2017
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  18. 18
    MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

    MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors by Kıvanç Birsoy, Timothy C. Wang, Richard Possemato, Ömer Yılmaz, Catherine Koch, Walter W. Chen, Amanda W. Hutchins, Yetiş Gültekin, Timothy R. Peterson, Jan E. Carette, Thijn R. Brummelkamp, Clary B. Clish, David M. Sabatini

    Published 2012
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  19. 19
    Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition

    Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition by Yoav D. Shaul, Elizaveta Freinkman, William C. Comb, Jason R. Cantor, Wai Leong Tam, Prathapan Thiru, Do‐Hoon Kim, Naama Kanarek, Michael E. Pacold, Walter W. Chen, Brian Bierie, Richard Possemato, Ferenc Reinhardt, Robert A. Weinberg, Michael B. Yaffe, David M. Sabatini

    Published 2014
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  20. 20
    Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

    Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy by Lin Wu, Kate E.R. Hollinshead, Yuhan Hao, Christy Au, Lina Kroehling, Charles Ng, Woan-Yu Lin, Dayi Li, Hernandez Moura Silva, Jong Shin, Juan J. Lafaille, Richard Possemato, Michael E. Pacold, Thales Papagiannakopoulos, Alec C. Kimmelman, Rahul Satija, Dan R. Littman

    Published 2020
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