Výsledky vyhledávání - Rhode, Peter

Points: Clinical Algorithms: Compulsory detention in hospital under the Mental Health Act 1983 Autor Rhode, Peter

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The IL-15-based superagonist ALT-803 promotes the antigen-independent conversion of memory CD8(+) T cells into innate-like effector cells with antitumor activity Autor Wong, Hing C, Jeng, Emily K, Rhode, Peter R

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Enhanced efficacy of IL-15-based ALT-803 superagonist complex in combination with immune checkpoint inhibitors in hematologic and metastatic mouse tumor models Autor Xu, Wenxin, Marcus, Warren D, Rhode, Peter R, Wong, Hing C

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Evaluation of a novel CD20-targeted IL-15 immunotherapeutic with potent activity against B cell lymphoma Autor Liu, Bai, Kong, Lin, Marcus, Warren D, Chen, Xiaoyue, Han, Kaiping, Rhode, Peter R, Wong, Hing C

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CITN-06: a Phase I/expansion trial of alt-803, an IL-15 superagonist, in patients with advanced melanoma Autor Margolin, Kim, Wong, Hing C, Morishima, Chihiro, Hernandez, Liza, Ernstoff, Marc, Rhode, Peter R, Waldmann, Thomas A

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A phase I study evaluating the pharmacokinetics, safety and tolerability of an antibody-based tissue factor antagonist in subjects with acute lung injury or acute respiratory distr... Autor Morris, Peter E, Steingrub, Jay S, Huang, Bee Y, Tang, Shamay, Liu, Patrick M, Rhode, Peter R, Wong, Hing C

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The IL-15 superagonist ALT-803 enhances anti-CD20 antibody-directed NK cell ADCC and in vivo clearance of B cell lymphomas Autor Rosario, Maximillian, Liu, Bai, Kong, Lin, Schneider, Stephanie E, Jeng, Emily K, Rhode, Peter R, Wong, Hing C, Fehniger, Todd A

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Effectiveness of two different dose administration regimens of an IL-15 superagonist complex (ALT-803) in an orthotopic bladder cancer mouse model Autor Furuya, Hideki, Chan, Owen T. M., Pagano, Ian, Zhu, Chengjun, Kim, Nari, Peres, Rafael, Hokutan, Kanani, Alter, Sarah, Rhode, Peter, Rosser, Charles J.

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Novel Human Interleukin-15 Agonists Autor Zhu, Xiaoyun, Marcus, Warren D., Xu, Wenxin, Lee, Hyung-Il, Han, Kaiping, Egan, Jack O., Yovandich, Jason L., Rhode, Peter R., Wong, Hing C.

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Evaluation of the biological activities of the IL-15 superagonist complex, ALT-803, following intravenous versus subcutaneous administration in murine models Autor Liu, Bai, Jones, Monica, Kong, Lin, Noel, Terra, Jeng, Emily K., Shi, Sixiang, England, Christopher G., Alter, Sarah, Miller, Jeffrey S., Cai, Weibo, Rhode, Peter R., Wong, Hing C.

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Novel antitumor mechanism-of-action of an IL-2 fusion protein mediated by tumor associated macrophage repolarization and innate-like CD8+ memory T cells Autor Xu, Wenxin, Egan, Jack O, Liu, Bai, Chen, Xiaoyue, You, Lijing, Han, Kaiping, Marcus, Warren D, Kong, Lin, Jones, Monica, Jeng, Emily K, Rhode, Peter R, Wong, Hing C

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Interleukin-15:Interleukin-15 receptor α scaffold for creation of multivalent targeted immune molecules Autor Wong, Richard L., Liu, Bai, Zhu, Xiaoyun, You, Lijing, Kong, Lin, Han, Kai-Ping, Lee, Hyung-il, Chavaillaz, Pierre-Andre, Jin, Moonsoo, Wang, Yi, Rhode, Peter R., Wong, Hing C.

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Phase 1 trial of ALT-801, an interleukin-2/T cell receptor fusion protein targeting p53 (aa264-272)/HLA-A*0201 complex, in patients with advanced malignancies Autor Fishman, Mayer N., Thompson, John A., Pennock, Gregory K., Gonzalez, Rene, Diez, Luz M., Daud, Adil I., Weber, Jeffery S., Huang, Bee Y., Tang, Shamay, Rhode, Peter R., Wong, Hing C.

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Intravesical ALT-803 and BCG Treatment Reduces Tumor Burden in a Carcinogen Induced Bladder Cancer Rat Model; a Role for Cytokine Production and NK Cell Expansion Autor Gomes-Giacoia, Evan, Miyake, Makito, Goodison, Steve, Sriharan, Aravindhan, Zhang, Ge, You, Lijing, Egan, Jack O., Rhode, Peter R., Parker, Alexander S., Chai, Karl X., Wong, Hing C., Rosser, Charles J.

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IL-15:IL-15 receptor alpha superagonist complex: High-level co-expression in recombinant mammalian cells, purification and characterization Autor Han, Kai-ping, Zhu, Xiaoyun, Liu, Bai, Jeng, Emily, Kong, Lin, Yovandich, Jason L., Vyas, Vinay V., Marcus, Warren D., Chavaillaz, Pierre-Andre, Romero, Christian A., Rhode, Peter R., Wong, Hing C.

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Efficacy and Mechanism-of-Action of a Novel Superagonist Interleukin-15: Interleukin-15 Receptor α/Fc Fusion Complex in Syngeneic Murine Models of Multiple Myeloma Autor Xu, Wenxin, Jones, Monica, Liu, Bai, Zhu, Xiaoyun, Johnson, C. Bryce, Edwards, Ana C., Kong, Lin, Jeng, Emily K., Han, Kaiping, Marcus, Warren D., Rubinstein, Mark P., Rhode, Peter R., Wong, Hing C.

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A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses Autor Liu, Bai, Kong, Lin, Han, Kaiping, Hong, Hao, Marcus, Warren D., Chen, Xiaoyue, Jeng, Emily K., Alter, Sarah, Zhu, Xiaoyun, Rubinstein, Mark P., Shi, Sixiang, Rhode, Peter R., Cai, Weibo, Wong, Hing C.

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Inhibition of Acute Vascular Thrombosis in Chimpanzees by an Anti-Human Tissue Factor Antibody Targeting the Factor X Binding Site Autor Jiao, Jin-an, Kelly, Andrew B., Marzec, Ulla M., Nieves, Esperanza, Acevedo, Jorge, Burkhardt, Martin, Edwards, Ana, Zhu, Xiao-yun, Chavaillaz, Pierre-Andre, Wong, Alice, Wong, Jeffrey L., Egan, Jack O., Taylor, Dean, Rhode, Peter R., Wong, Hing C.

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Immunotherapeutic HCW9218 augments anti-tumor activity of chemotherapy via NK cell-mediated reduction of therapy-induced senescent cells Autor Chaturvedi, Pallavi, George, Varghese, Shrestha, Niraj, Wang, Meng, Dee, Michael J., Zhu, Xiaoyun, Liu, Bai, Egan, Jack, D'Eramo, Francesca, Spanoudis, Catherine, Gallo, Victor, Echeverri, Christian, You, Lijing, Kong, Lin, Fang, Byron, Jeng, Emily K., Rhode, Peter R., Wong, Hing C.

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PHASE I TRIAL OF ALT-803, A NOVEL RECOMBINANT INTERLEUKIN-15 COMPLEX, IN PATIENTS WITH ADVANCED SOLID TUMORS Autor Margolin, Kim, Morishima, Chihiro, Velcheti, Vamsidhar, Miller, Jeffrey S., Lee, Sylvia M., Silk, Ann W., Holtan, Shernan G., Lacroix, Andreanne M., Fling, Steven P., Kaiser, Judith C., Egan, Jack O., Jones, Monica, Rhode, Peter R., Rock, Amy D., Cheever, Martin A., Wong, Hing C., Ernstoff, Marc S.

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