Suchergebnisse - Remco M. Hoogenboezem

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  1. 1
    Yap1-Driven Intestinal Repair Is Controlled by Group 3 Innate Lymphoid Cells

    Yap1-Driven Intestinal Repair Is Controlled by Group 3 Innate Lymphoid Cells von Mónica Romera‐Hernández, Patricia Aparicio‐Domingo, Natalie Papazian, Julien J. Karrich, Ferry Cornelissen, Remco M. Hoogenboezem, Janneke N. Samsom, Tom Cupedo

    Veröffentlicht 2020
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  2. 2
    Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways

    Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways von Stefan Gröschel, Mathijs A. Sanders, Remco M. Hoogenboezem, Annelieke Zeilemaker, Marije Havermans, Claudia Erpelinck-Verschueren, Eric M. Bindels, H. Berna Beverloo, Hartmut Döhner, Bob Löwenberg, Konstanze Döhner, Ruud Delwel, Peter J.M. Valk

    Veröffentlicht 2014
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  3. 3
    Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes

    Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes von Noemi A. Zambetti, Eric M. Bindels, Paulina M. H. van Strien, Marijke Valkhof, Maria Niken Adisty, Remco M. Hoogenboezem, Matthew A. Sanders, Johanna M. Rommens, Ivo P. Touw, Marc H.G.P. Raaijmakers

    Veröffentlicht 2015
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  4. 4
    Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling

    Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling von Erdogan Taskesen, Marije Havermans, Kirsten van Lom, Mathijs A. Sanders, Yvette van Norden, Eric M. Bindels, Remco M. Hoogenboezem, Marcel J. T. Reinders, María E. Figueroa, Peter J.M. Valk, Bob Löwenberg, Ari Melnick, Ruud Delwel

    Veröffentlicht 2014
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  5. 5
    Massive parallel RNA sequencing of highly purified mesenchymal elements in low-risk MDS reveals tissue-context-dependent activation of inflammatory programs

    Massive parallel RNA sequencing of highly purified mesenchymal elements in low-risk MDS reveals tissue-context-dependent activation of inflammatory programs von S Chen, Noemi A. Zambetti, Eric M. Bindels, K. Kenswill, Athina Mylona, Niken Adisty, Remco M. Hoogenboezem, Mathijs A. Sanders, Eline M.P. Cremers, Theresia M. Westers, Joop H. Jansen, Arjan A. van de Loosdrecht, Marc H.G.P. Raaijmakers

    Veröffentlicht 2016
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  6. 6
    Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence

    Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence von Kristine Misund, Davine Hofste op Bruinink, Eivind Coward, Remco M. Hoogenboezem, Even H Rustad, Mathijs A. Sanders, Morten Beck Rye, Anne‐Marit Sponaas, Bronno van der Holt, Sonja Zweegman, Eivind Hovig, Leonardo A. Meza‐Zepeda, Anders Sundan, Ola Myklebost, Pieter Sonneveld, Anders Waage

    Veröffentlicht 2022
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  7. 7
    Characterization of Endothelial Cells Associated with Hematopoietic Niche Formation in Humans Identifies IL-33 As an Anabolic Factor

    Characterization of Endothelial Cells Associated with Hematopoietic Niche Formation in Humans Identifies IL-33 As an Anabolic Factor von Keane Jared Guillaume Kenswil, Adrian Christopher Jaramillo, Zhen Ping, Si Chen, Remco M. Hoogenboezem, Maria Mylona, Maria Niken Adisty, Eric Moniqué Johannes Bindels, P.K. Bos, Hans Stoop, King H. Lam, Bram C. J. van der Eerden, Tom Cupedo, Marc Hermanus Gerardus Petrus Raaijmakers

    Veröffentlicht 2018
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  8. 8
    A Single-Cell Taxonomy Predicts Inflammatory Niche Remodeling to Drive Tissue Failure and Outcome in Human AML

    A Single-Cell Taxonomy Predicts Inflammatory Niche Remodeling to Drive Tissue Failure and Outcome in Human AML von Lanpeng Chen, Eline Pronk, Claire van Dijk, Yujie Bian, Jacqueline Feyen, Tim van Tienhoven, Meltem Yildirim, Paola Pisterzi, Madelon M.E. de Jong, Alejandro Bastidas, Remco M. Hoogenboezem, Chiel Wevers, Eric M. Bindels, Bob Löwenberg, Tom Cupedo, Mathijs A. Sanders, Marc H.G.P. Raaijmakers

    Veröffentlicht 2023
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  9. 9
    Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation

    Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation von Manzhi Zhao, Caoimhe H. Kiernan, Christopher J. Stairiker, Jennifer L. Hope, Leticia G. León, Marjan van Meurs, Inge Brouwers-Haspels, Ruben Boers, Joachim Boers, Joost Gribnau, Wilfred F. J. van IJcken, Eric M. Bindels, Remco M. Hoogenboezem, Stefan J. Erkeland, Yvonne M. Mueller, Peter D. Katsikis

    Veröffentlicht 2020
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  10. 10
    Gli1 + Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target

    Gli1 + Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target von Rebekka K. Schneider, Ann Mullally, Aurélien Dugourd, Fabian Peisker, Remco M. Hoogenboezem, Paulina M. H. van Strien, Eric M. Bindels, Dirk Heckl, Guntram Büsche, David Fleck, Gerhard Müller‐Newen, Janewit Wongboonsin, Mónica Ventura Ferreira, Victor G. Puelles, Julio Sáez-Rodríguez, Benjamin L. Ebert, Benjamin D. Humphreys, Rafael Kramann

    Veröffentlicht 2017
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  11. 11
    Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN

    Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN von Hélène F.E. Gleitz, Aurélien Dugourd, Nils B. Leimkühler, Inge Snoeren, Stijn Fuchs, Sylvia Menzel, Susanne Ziegler, Nicolaus Kröger, Ioanna Triviai, Guntram Büsche, Hans Kreipe, Bella Banjanin, Jessica E. Pritchard, Remco M. Hoogenboezem, Eric M. Bindels, Neele Schumacher, Stefan Rose‐John, Shannon Elf, Julio Sáez-Rodríguez, Rafael Kramann, Rebekka K. Schneider

    Veröffentlicht 2020
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  12. 12
    Evidence for altered immune-structural cell crosstalk in cystic fibrosis revealed by single cell transcriptomics

    Evidence for altered immune-structural cell crosstalk in cystic fibrosis revealed by single cell transcriptomics von Marijn Berg, Lisette Krabbendam, Esmee K. van der Ploeg, Menno van Nimwegen, Tjeerd van der Veer, Martin Banchero, Orestes A. Carpaij, Remco M. Hoogenboezem, Maarten van den Berge, Eric M. Bindels, Joachim G.J.V. Aerts, Anne Collin, Pascal Barbry, Lieke S. Kamphuis, Rudi W. Hendriks, Martijn C. Nawijn, Ralph Stadhouders

    Veröffentlicht 2025
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  13. 13
    ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation

    ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation von Mir Farshid Alemdehy, Jurgen R. Haanstra, Hans W. J. de Looper, Paulina M. H. van Strien, Judith Verhagen-Oldenampsen, Yvette Caljouw, Mathijs A. Sanders, Remco M. Hoogenboezem, Arnoud H. de Ru, George M. C. Janssen, Stephanie E. Smetsers, Marc Bierings, Peter A. van Veelen, Marieke von Lindern, Ivo P. Touw, Stefan J. Erkeland

    Veröffentlicht 2015
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  14. 14
    MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

    MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML von Mathijs A. Sanders, Edward Chew, Christoffer Flensburg, Annelieke Zeilemaker, Sarah E. Miller, Adil S. A. Al Hinai, Ashish Bajel, Bram Luiken, Melissa Rijken, Tamara J. McLennan, Remco M. Hoogenboezem, François G. Kavelaars, Stefan Fröhling, Marnie E. Blewitt, Eric M. Bindels, Warren S. Alexander, Bob Löwenberg, Andrew W. Roberts, Peter J.M. Valk, Ian J. Majewski

    Veröffentlicht 2018
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  15. 15
    An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation

    An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation von Roberto Avellino, Marije Havermans, Claudia Erpelinck-Verschueren, Mathijs A. Sanders, Remco M. Hoogenboezem, Harmen J.G. van de Werken, Elwin Rombouts, Kirsten van Lom, Paulina M. H. van Strien, Claudia Gebhard, Michael Rehli, John E. Pimanda, Dominik Beck, Stefan J. Erkeland, Thijs Kuiken, Hans de Looper, Stefan Gröschel, Ivo P. Touw, Eric M. Bindels, Ruud Delwel

    Veröffentlicht 2016
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  16. 16
    Identification of High-Risk Multiple Myeloma With a Plasma Cell Leukemia-Like Transcriptomic Profile

    Identification of High-Risk Multiple Myeloma With a Plasma Cell Leukemia-Like Transcriptomic Profile von Davine Hofste op Bruinink, Rowan Kuiper, Mark van Duin, Tom Cupedo, Vincent H. J. van der Velden, Remco M. Hoogenboezem, Bronno van der Holt, H. Berna Beverloo, Erik T. Valent, Michael Vermeulen, Francesca Gay, Annemiek Broijl, Hervé Avet‐Loiseau, Nikhil C. Munshi, Pellegrino Musto, Philippe Moreau, Sonja Zweegman, Niels W.C.J. van de Donk, Pieter Sonneveld

    Veröffentlicht 2022
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  17. 17
    A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia

    A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia von Stefan Gröschel, Mathijs A. Sanders, Remco M. Hoogenboezem, Elzo de Wit, Britta A. M. Bouwman, Claudia Erpelinck-Verschueren, Vincent H. J. van der Velden, Marije Havermans, Roberto Avellino, Kirsten van Lom, Elwin Rombouts, Mark van Duin, Konstanze Döhner, H. Berna Beverloo, James E. Bradner, Hartmut Döhner, Bob Löwenberg, Peter J.M. Valk, Eric M. Bindels, Wouter de Laat, Ruud Delwel

    Veröffentlicht 2014
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  18. 18
    Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation

    Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation von Keane Jared Guillaume Kenswil, Paola Pisterzi, Gonzalo Sánchez‐Duffhues, Claire van Dijk, Andrea Lolli, Callie Knuth, Byambasuren Vanchin, Adrian Christopher Jaramillo, Remco M. Hoogenboezem, Mathijs A. Sanders, Jacqueline Feyen, Tom Cupedo, Ivan G. Costa, Ronghui Li, Eric Moniqué Johannes Bindels, Kirsten Lodder, Bianca Blom, P.K. Bos, Marie‐José Goumans, Peter ten Dijke, Eric Farrell, Guido Krenning, Marc Hermanus Gerardus Petrus Raaijmakers

    Veröffentlicht 2021
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  19. 19
    Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis

    Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis von Julia Skokowa, Doris Steinemann, Jenny E. Katsman-Kuipers, Cornelia Zeidler, Olga Klimenkova, Maksim Klimiankou, Murat Ünalan, Siarhei Kandabarau, Vahagn Makaryan, Renée Beekman, Kira Behrens, Carol Stocking, Julia C. Obenauer, Susanne Schnittger, Alexander Kohlmann, Marijke Valkhof, Remco M. Hoogenboezem, Gudrun Göhring, Dirk Reinhardt, Brigitte Schlegelberger, Martin Stanulla, Peter Vandenberghe, Jean Donadieu, C. Michel Zwaan, Ivo P. Touw, Marry M. van den Heuvel‐Eibrink, David C. Dale, Karl Welte

    Veröffentlicht 2014
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  20. 20
    Decoding myofibroblast origins in human kidney fibrosis

    Decoding myofibroblast origins in human kidney fibrosis von Christoph Kuppe, Mahmoud M. Ibrahim, Jennifer Kranz, Xiaoting Zhang, Susanne Ziegler, Javier Perales-Patón, Jitske Jansen, Katharina C. Reimer, James R. Smith, Ross Dobie, John R. Wilson‐Kanamori, Maurice Halder, Yaoxian Xu, Nazanin Kabgani, Nadine Kaesler, Martin Klaus, Lukas Gernhold, Victor G. Puelles, Tobias B. Huber, Peter Boor, Sylvia Menzel, Remco M. Hoogenboezem, Eric M. Bindels, J. Steffens, Jürgen Floege, Rebekka K. Schneider, Julio Sáez-Rodríguez, Neil C. Henderson, Rafael Kramann

    Veröffentlicht 2020
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