Suchergebnisse - Relja Popovic

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  1. 1
    Emerging Epigenetic Targets and Therapies in Cancer Medicine

    Emerging Epigenetic Targets and Therapies in Cancer Medicine von Relja Popovic, Jonathan D. Licht

    Veröffentlicht 2012
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  2. 2
    Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia

    Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia von Tomasz Cierpicki, Laurie E. Risner, Jolanta Grembecka, Stephen M. Lukasik, Relja Popovic, Monika Omonkowska, David Shultis, Nancy J. Zeleznik‐Le, John H. Bushweller

    Veröffentlicht 2009
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  3. 3
    Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3

    Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3 von Yupeng Zheng, Steve M. M. Sweet, Relja Popovic, Eva Martínez-García, Jeremiah D. Tipton, Paul M. Thomas, Jonathan D. Licht, Neil L. Kelleher

    Veröffentlicht 2012
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  4. 4
    MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC

    MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC von D-J Min, Teresa Ezponda, M K Kim, Christine Will, Eva Martínez-García, Relja Popovic, Venkatesha Basrur, Kojo S.J. Elenitoba‐Johnson, Jonathan D. Licht

    Veröffentlicht 2012
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  5. 5
    A phase 1 study of the pan‐bromodomain and extraterminal inhibitor mivebresib (ABBV‐075) alone or in combination with venetoclax in patients with relapsed/refractory acute myeloid leukemia

    A phase 1 study of the pan‐bromodomain and extraterminal inhibitor mivebresib (ABBV‐075) alone or in combination with venetoclax in patients with relapsed/refractory acute myeloid... von Gautam Borthakur, Olatoyosi Odenike, Ibrahim Aldoss, David A. Rizzieri, Thomas Prébet, Christopher S. Chen, Relja Popovic, Dimple Modi, Rujuta Joshi, Johannes Wolff, Brian A. Jonas

    Veröffentlicht 2021
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  6. 6
    The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial–mesenchymal transition and invasive properties of prostate cancer

    The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial–mesenchymal transition and invasive properties of prostate cancer von Teresa Ezponda, Relja Popovic, Maitri Shah, Eva Martínez-García, Yupeng Zheng, D-J Min, Christine Will, Antonino Neri, Neil L. Kelleher, Jian Yu, Jonathan D. Licht

    Veröffentlicht 2012
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  7. 7
    MLL protects CpG clusters from methylation within the <i>Hoxa9</i> gene, maintaining transcript expression

    MLL protects CpG clusters from methylation within the <i>Hoxa9</i> gene, maintaining transcript expression von Frank Erfurth, Relja Popovic, Jolanta Grembecka, Tomasz Cierpicki, Catherine Theisler, Zhen-Biao Xia, Tara Stuart, Manuel O. Dı́az, John H. Bushweller, Nancy J. Zeleznik‐Le

    Veröffentlicht 2008
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  8. 8
    GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1

    GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1 von Krishan Kumar, Sania S. Raza, Lawrence M. Knab, Christina R. Chow, Benjamin Kwok, David J. Bentrem, Relja Popovic, Kazumi Ebine, Jonathan D. Licht, Hidayatullah G. Munshi

    Veröffentlicht 2015
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  9. 9
    5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-Mediated Apoptosis

    5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-Mediated Apoptosis von Sha Jin, Dan Cojocari, Julie J. Purkal, Relja Popovic, Nari Talaty, Xiao Yu, Larry R. Solomon, Erwin R. Boghaert, Joel D. Leverson, Darren C. Phillips

    Veröffentlicht 2020
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  10. 10
    Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape

    Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape von Behnam Nabet, Pilib Ó Broin, Jaime M. Reyes, Kevin Shieh, Charles Y. Lin, Christine Will, Relja Popovic, Teresa Ezponda, James E. Bradner, Aaron A. Golden, Jonathan D. Licht

    Veröffentlicht 2015
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  11. 11
    Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

    Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization von Relja Popovic, Laurie E. Riesbeck, Chinavenmeni S. Velu, Aditya Chaubey, Jiwang Zhang, Nicholas J. Achille, Frank Erfurth, Katherine Eaton, Jun Lü, H. Leighton Grimes, Jianjun Chen, Janet D. Rowley, Nancy J. Zeleznik‐Le

    Veröffentlicht 2009
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  12. 12
    MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents

    MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents von Maitri Shah, Eva Martínez-García, Jude M. Phillip, Allison B Chambliss, Relja Popovic, Teresa Ezponda, Eliza C. Small, Christine Will, Madonna P. Phillip, Paola Neri, Nizar J. Bahlis, Denis Wirtz, Jonathan D. Licht

    Veröffentlicht 2016
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  13. 13
    The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells

    The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells von Eva Martínez-García, Relja Popovic, Dong Joon Min, Steve M. M. Sweet, Paul M. Thomas, Leonid Zamdborg, Aaron Heffner, Christine Will, Laurence Lamy, Louis M. Staudt, David Levens, Neil L. Kelleher, Jonathan D. Licht

    Veröffentlicht 2010
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  14. 14
    Genetic biomarkers of sensitivity and resistance to venetoclax monotherapy in patients with relapsed acute myeloid leukemia

    Genetic biomarkers of sensitivity and resistance to venetoclax monotherapy in patients with relapsed acute myeloid leukemia von Brenda Chyla, Naval Daver, Kelly Doyle, Evelyn McKeegan, Xin Huang, Vivian Ruvolo, Zixing Wang, Ken Chen, Andrew J. Souers, Joel D. Leverson, Jalaja Potluri, Erwin R. Boghaert, Anahita Bhathena, Marina Konopleva, Relja Popovic

    Veröffentlicht 2018
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  15. 15
    Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies

    Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies von Jon A. Oyer, Xiaoxiao Huang, Yupeng Zheng, J. Shim, Teresa Ezponda, Zachary Carpenter, Maddalena Allegretta, C I Okot-Kotber, Jay Pravin Patel, Ashley Melnick, Ross L. Levine, Adolfo A. Ferrando, Alexander D. MacKerell, Neil L. Kelleher, Jonathan D. Licht, Relja Popovic

    Veröffentlicht 2013
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  16. 16
    Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation

    Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation von Relja Popovic, Eva Martínez-García, Ευγενία Γιαννοπούλου, Quanwei Zhang, Qingyang Zhang, Teresa Ezponda, Mrinal Y. Shah, Yupeng Zheng, Christine Will, Eliza C. Small, Youjia Hua, Marinka Bulic, Yanwen Jiang, Matteo Carrara, Raffaele Calogero, William L. Kath, Neil L. Kelleher, Ji-Ping Wang, Olivier Elemento, Jonathan D. Licht

    Veröffentlicht 2014
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  17. 17
    UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition

    UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition von Teresa Ezponda, Daphné Dupéré-Richer, Christine Will, Eliza C. Small, Nobish Varghese, Tej Patel, Behnam Nabet, Relja Popovic, Jon A. Oyer, Marinka Bulic, Yupeng Zheng, Xiaoxiao Huang, Mrinal Y. Shah, Sayantan Maji, Alberto Riva, Manuela Occhionorelli, Giovanni Tonon, Neil L. Kelleher, Jonathan J. Keats, Jonathan D. Licht

    Veröffentlicht 2017
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  18. 18
    Six-year follow-up and subgroup analyses of a phase 2 trial of venetoclax for del(17p) chronic lymphocytic leukemia

    Six-year follow-up and subgroup analyses of a phase 2 trial of venetoclax for del(17p) chronic lymphocytic leukemia von Stephan Stilgenbauer, Eugen Tausch, Andrew W. Roberts, Matthew S. Davids, Barbara Eichhorst, Michael Hallek, Peter Hillmen, Christof Schneider, Johannes Schetelig, Sebastian Böttcher, Arnon P. Kater, Yanwen Jiang, Michelle Boyer, Relja Popovic, Majd T. Ghanim, Michael Moran, Wendy Sinai, Xifeng Wang, Nabanita Mukherjee, Brenda Chyla, William G. Wierda, John F. Seymour

    Veröffentlicht 2024
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  19. 19
    The MURANO study: final analysis and retreatment/crossover substudy results of VenR for patients with relapsed/refractory CLL

    The MURANO study: final analysis and retreatment/crossover substudy results of VenR for patients with relapsed/refractory CLL von Arnon P. Kater, Rosemary Harrup, Thomas J. Kipps, Barbara Eichhorst, Carolyn Owen, Sarit Assouline, Nicole Lamanna, Tadeusz Robak, Javier de la Serna, Ulrich Jäger, Guillaume Cartron, Marco Montillo, Clemens Mellink, Anton W. Langerak, Brenda Chyla, Relja Popovic, Yanwen Jiang, Rosemary Millen, Marcus Lefebure, Maria Thadani‐Mulero, Michelle Boyer, John F. Seymour

    Veröffentlicht 2025
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  20. 20
    Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study

    Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study von Andrew H. Wei, Stephen A. Strickland, Jing-Zhou Hou, Walter Fiedler, Tara L. Lin, Roland B. Walter, Anoop K. Enjeti, Ing Soo Tiong, Michael R. Savona, Sang‐Min Lee, Brenda Chyla, Relja Popovic, Ahmed Hamed Salem, Suresh Agarwal, Tu Xu, Kaffa Fakouhi, Rod Humerickhouse, Wan-Jen Hong, John Hayslip, Gail J. Roboz

    Veröffentlicht 2019
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