Kết quả tìm kiếm - Reader, Janette

Adapt or Die: Targeting Unique Transmission-Stage Biology for Malaria Elimination Bằng van der Watt, Mariëtte E., Reader, Janette, Birkholtz, Lyn-Marié

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Streamlined and Robust Stage-Specific Profiling of Gametocytocidal Compounds Against Plasmodium falciparum Bằng Reader, Janette, van der Watt, Mariette E., Birkholtz, Lyn-Marié

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Differential activity of novel gametocytocidal compounds: drug mode-of-action and ex vivo efficacy Bằng Birkholtz, Lyn-Marie, LeRoy, Didier, Reader, Janette, Botha, Mariette, Mancama, Dalu, Coetzer, Theresa L

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H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum Bằng Connacher, Jessica, Josling, Gabrielle A., Orchard, Lindsey M., Reader, Janette, Llinás, Manuel, Birkholtz, Lyn-Marié

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Epigenetic inhibitors target multiple stages of Plasmodium falciparum parasites Bằng Coetzee, Nanika, von Grüning, Hilde, Opperman, Daniel, van der Watt, Mariette, Reader, Janette, Birkholtz, Lyn-Marié

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The ecdysone receptor regulates several key physiological factors in Anopheles funestus Bằng Maharaj, Surina, Ekoka, Elodie, Erlank, Erica, Nardini, Luisa, Reader, Janette, Birkholtz, Lyn-Marie, Koekemoer, Lizette L.

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A Dynamic and Combinatorial Histone Code Drives Malaria Parasite Asexual and Sexual Development Bằng von Grüning, Hilde, Coradin, Mariel, Mendoza, Mariel R., Reader, Janette, Sidoli, Simone, Garcia, Benjamin A., Birkholtz, Lyn-Marié

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Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation Bằng van Biljon, Riëtte, van Wyk, Roelof, Painter, Heather J., Orchard, Lindsey, Reader, Janette, Niemand, Jandeli, Llinás, Manuel, Birkholtz, Lyn-Marie

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Adsorption to the surface of hemozoin crystals: Structure-based design and synthesis of new amino-phenoxazine β-hematin inhibitors Bằng Olivier, Tania, Loots, Leigh, Kok, Michélle, de Villiers, Marianne, Reader, Janette, Birkholtz, Lyn-Marié, Arnott, Gareth E., de Villiers, Katherine A.

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Structure–Activity Relationship Studies Reveal New Astemizole Analogues Active against Plasmodium falciparum In Vitro Bằng Mambwe, Dickson, Kumar, Malkeet, Ferger, Richard, Taylor, Dale, Njoroge, Mathew, Coertzen, Dina, Reader, Janette, van der Watt, Mariëtte, Birkholtz, Lyn-Marie, Chibale, Kelly

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Anthracene-Polyamine Conjugates Inhibit In Vitro Proliferation of Intraerythrocytic Plasmodium falciparum Parasites Bằng Niemand, Jandeli, Burger, Pieter, Verlinden, Bianca K., Reader, Janette, Joubert, Annie M., Kaiser, Annette, Louw, Abraham I., Kirk, Kiaran, Phanstiel, Otto, Birkholtz, Lyn-Marie

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The Artemiside-Artemisox-Artemisone-M1 Tetrad: Efficacies against Blood Stage P. falciparum Parasites, DMPK Properties, and the Case for Artemiside Bằng Gibhard, Liezl, Coertzen, Dina, Reader, Janette, van der Watt, Mariëtte E., Birkholtz, Lyn-Marie, Wong, Ho Ning, Batty, Kevin T., Haynes, Richard K., Wiesner, Lubbe

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Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination Bằng Reader, Janette, Botha, Mariëtte, Theron, Anjo, Lauterbach, Sonja B, Rossouw, Claire, Engelbrecht, Dewaldt, Wepener, Melanie, Smit, Annél, Leroy, Didier, Mancama, Dalu, Coetzer, Theresa L, Birkholtz, Lyn-Marie

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Naphthylisoquinoline alkaloids, validated as hit multistage antiplasmodial natural products Bằng Moyo, Phanankosi, Shamburger, William, van der Watt, Mariëtte E., Reader, Janette, de Sousa, Ana Carolina C., Egan, Timothy J., Maharaj, Vinesh J., Bringmann, Gerhard, Birkholtz, Lyn-Marie

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Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasit... Bằng Verlinden, Bianca K., de Beer, Marna, Pachaiyappan, Boobalan, Besaans, Ethan, Andayi, Warren A., Reader, Janette, Niemand, Jandeli, van Biljon, Riette, Guy, Kiplin, Egan, Timothy, Woster, Patrick M., Birkholtz, Lyn-Marie

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Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites Bằng van Biljon, Riëtte, Niemand, Jandeli, van Wyk, Roelof, Clark, Katherine, Verlinden, Bianca, Abrie, Clarissa, von Grüning, Hilde, Smidt, Werner, Smit, Annél, Reader, Janette, Painter, Heather, Llinás, Manuel, Doerig, Christian, Birkholtz, Lyn-Marié

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Optimal 10-Aminoartemisinins With Potent Transmission-Blocking Capabilities for New Artemisinin Combination Therapies–Activities Against Blood Stage P. falciparum Including PfKI3 C... Bằng Wong, Ho Ning, Padín-Irizarry, Vivian, van der Watt, Mariëtte E., Reader, Janette, Liebenberg, Wilna, Wiesner, Lubbe, Smith, Peter, Eribez, Korina, Winzeler, Elizabeth A., Kyle, Dennis E., Birkholtz, Lyn-Marie, Coertzen, Dina, Haynes, Richard K.

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Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages Bằng Coertzen, Dina, Reader, Janette, van der Watt, Mariëtte, Nondaba, Sindisiwe H., Gibhard, Liezl, Wiesner, Lubbe, Smith, Peter, D'Alessandro, Sarah, Taramelli, Donatella, Wong, Ho Ning, du Preez, Jan L., Wu, Ronald Wai Keung, Birkholtz, Lyn-Marie, Haynes, Richard K.

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Discovery of Compounds Blocking the Proliferation of Toxoplasma gondii and Plasmodium falciparum in a Chemical Space Based on Piperidinyl-Benzimidazolone Analogs Bằng Saïdani, Nadia, Botté, Cyrille Y., Deligny, Michael, Bonneau, Anne-Laure, Reader, Janette, Lasselin, Ronald, Merer, Goulven, Niepceron, Alisson, Brossier, Fabien, Cintrat, Jean-Christophe, Rousseau, Bernard, Birkholtz, Lyn-Marie, Cesbron-Delauw, Marie-France, Dubremetz, Jean-François, Mercier, Corinne, Vial, Henri, Lopez, Roman, Maréchal, Eric

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Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer Bằng Abacha, Yabalu Z., Forkuo, Arnold Donkor, Gbedema, Stephen Y., Mittal, Nimisha, Ottilie, Sabine, Rocamora, Frances, Winzeler, Elizabeth A., van Schalkwyk, Donelly A., Kelly, John M., Taylor, Martin C., Reader, Janette, Birkholtz, Lyn-Marie, Lisgarten, David R., Cockcroft, Jeremy K., Lisgarten, John N., Palmer, Rex A., Talbert, Rosemary C., Shnyder, Steven D., Wright, Colin W.

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