Výsledky vyhledávání - Rapeport, Garth

In Vivo Biomarker Analysis of the Effects of Intranasally Dosed PC945, a Novel Antifungal Triazole, on Aspergillus fumigatus Infection in Immunocompromised Mice Autor Kimura, Genki, Nakaoki, Takahiro, Colley, Thomas, Rapeport, Garth, Strong, Pete, Ito, Kazuhiro, Kizawa, Yasuo

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1335. Safety and Pharmacokinetic Profile of PC786, a Novel Inhibitor of Respiratory Syncytial Virus L-protein Polymerase, in a Single and Multiple-Ascending Dose Study in Healthy V... Autor Cass, Lindsey, Davis, Amanda, Murray, Alison, Woodward, Kathy, Ito, Kazuhiro, Strong, Pete, Rapeport, Garth

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Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway Autor Coates, Matthew S., Alton, Eric W. F. W., Rapeport, Garth W., Davies, Jane C., Ito, Kazuhiro

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Antifungal synergy of a topical triazole, PC945, with a systemic triazole against respiratory Aspergillus fumigatus infection Autor Colley, Thomas, Sehra, Gurpreet, Daly, Leah, Kimura, Genki, Nakaoki, Takahiro, Nishimoto, Yuki, Kizawa, Yasuo, Strong, Pete, Rapeport, Garth, Ito, Kazuhiro

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Reduced Nasal Viral Load and IFN Responses in Infants with Respiratory Syncytial Virus Bronchiolitis and Respiratory Failure Autor Thwaites, Ryan S., Coates, Matthew, Ito, Kazuhiro, Ghazaly, Marwa, Feather, Calandra, Abdulla, Farhana, Tunstall, Tanushree, Jain, Pooja, Cass, Lindsey, Rapeport, Garth, Hansel, Trevor T., Nadel, Simon, Openshaw, Peter

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In vitro antifungal activity of a novel topical triazole PC945 against emerging yeast Candida auris Autor Rudramurthy, Shivaprakash M, Colley, Thomas, Abdolrasouli, Alireza, Ashman, Jed, Dhaliwal, Manpreet, Kaur, Harsimran, Armstrong-James, Darius, Strong, Pete, Rapeport, Garth, Schelenz, Silke, Ito, Kazuhiro, Chakrabarti, Arunaloke

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Nasosorption as a Minimally Invasive Sampling Procedure: Mucosal Viral Load and Inflammation in Primary RSV Bronchiolitis Autor Thwaites, Ryan S., Ito, Kazuhiro, Chingono, Jasmine M. S., Coates, Matthew, Jarvis, Hannah C., Tunstall, Tanushree, Anderson-Dring, Lauren, Cass, Lindsey, Rapeport, Garth, Openshaw, Peter J., Nadel, Simon, Hansel, Trevor T.

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Late therapeutic intervention with a respiratory syncytial virus L‐protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium Autor Brookes, Daniel W, Coates, Matthew, Allen, Heather, Daly, Leah, Constant, Samuel, Huang, Song, Hows, Mark, Davis, Amanda, Cass, Lindsey, Ayrton, John, Knowles, Ian, Strong, Pete, Rapeport, Garth, Ito, Kazuhiro

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Anti-fungal activity of a novel triazole, PC1244, against emerging azole-resistant Aspergillus fumigatus and other species of Aspergillus Autor Colley, Thomas, Sharma, Cheshta, Alanio, Alexandre, Kimura, Genki, Daly, Leah, Nakaoki, Takahiro, Nishimoto, Yuki, Bretagne, Stéphane, Kizawa, Yasuo, Strong, Pete, Rapeport, Garth, Ito, Kazuhiro, Meis, Jacques F, Chowdhary, Anuradha

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Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent Autor Cass, Lindsey, Murray, Alison, Davis, Amanda, Woodward, Kathy, Albayaty, Muna, Ito, Kazuhiro, Strong, Pete, Ayrton, John, Brindley, Charlie, Prosser, Jayne, Murray, John, French, Eddie, Haywood, Phillip, Wallis, Christopher, Rapeport, Garth

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Safety and Antiviral Effects of Nebulized PC786 in a Respiratory Syncytial Virus Challenge Study Autor DeVincenzo, John, Cass, Lindsey, Murray, Alison, Woodward, Kathy, Meals, Elizabeth, Coates, Matthew, Daly, Leah, Wheeler, Vicky, Mori, Julie, Brindley, Charlie, Davis, Amanda, McCurdy, Meabh, Ito, Kazuhiro, Murray, Bryan, Strong, Pete, Rapeport, Garth

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Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor Autor Coates, Matthew, Brookes, Daniel, Kim, Young-In, Allen, Heather, Fordyce, Euan A. F., Meals, Elizabeth A., Colley, Thomas, Ciana, Claire-Lise, Parra, Guillaume F., Sherbukhin, Vladimir, Stockwell, Jennifer A., Thomas, Jennifer C., Hunt, S. Fraser, Anderson-Dring, Lauren, Onions, Stuart T., Cass, Lindsey, Murray, Peter J., Ito, Kazuhiro, Strong, Pete, DeVincenzo, John P., Rapeport, Garth

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In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection Autor Colley, Thomas, Alanio, Alexandre, Kelly, Steven L., Sehra, Gurpreet, Kizawa, Yasuo, Warrilow, Andrew G. S., Parker, Josie E., Kelly, Diane E., Kimura, Genki, Anderson-Dring, Lauren, Nakaoki, Takahiro, Sunose, Mihiro, Onions, Stuart, Crepin, Damien, Lagasse, Franz, Crittall, Matthew, Shannon, Jonathan, Cooke, Michael, Bretagne, Stéphane, King-Underwood, John, Murray, John, Ito, Kazuhiro, Strong, Pete, Rapeport, Garth

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In Vitro and In Vivo Efficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, on Aspergillus fumigatus Infection Autor Colley, Thomas, Sehra, Gurpreet, Chowdhary, Anuradha, Alanio, Alexandre, Kelly, Steven L., Kizawa, Yasuo, Armstrong-James, Darius, Fisher, Matthew C., Warrilow, Andrew G. S., Parker, Josie E., Kelly, Diane E., Kimura, Genki, Nishimoto, Yuki, Sunose, Mihiro, Onions, Stuart, Crepin, Damien, Lagasse, Franz, Crittall, Matthew, Shannon, Jonathan, McConville, Matthew, King-Underwood, John, Naylor, Alan, Bretagne, Stéphane, Murray, John, Ito, Kazuhiro, Strong, Pete, Rapeport, Garth

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Safety, tolerability, viral kinetics, and immune correlates of protection in healthy, seropositive UK adults inoculated with SARS-CoV-2: a single-centre, open-label, phase 1 contro... Autor Jackson, Susan, Marshall, Julia L, Mawer, Andrew, Lopez-Ramon, Raquel, Harris, Stephanie A, Satti, Iman, Hughes, Eileen, Preston-Jones, Hannah, Puig, Ingrid Cabrera, Longet, Stephanie, Tipton, Tom, Laidlaw, Stephen, Doherty, Rebecca Powell, Morrison, Hazel, Mitchell, Robert, Tanner, Rachel, Ateere, Alberta, Stylianou, Elena, Wu, Meng-San, Fredsgaard-Jones, Timothy P W, Breuer, Judith, Rapeport, Garth, Ferreira, Vanessa M, Gleeson, Fergus, Pollard, Andrew J, Carroll, Miles, Catchpole, Andrew, Chiu, Christopher, McShane, Helen

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