Search Results - Ralph Mazitschek

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  1. 1
    A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader

    A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader by N. Connor Payne, Semer Maksoud, Bakhos A. Tannous, Ralph Mazitschek

    Published 2022
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  2. 2
    Fluorescence anisotropy imaging in drug discovery

    Fluorescence anisotropy imaging in drug discovery by Claudio Vinegoni, Paolo Fumene Feruglio, Ignacy Gryczyński, Ralph Mazitschek, Ralph Weissleder

    Published 2018
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  3. 3
    Treatment of Obesity with Celastrol

    Treatment of Obesity with Celastrol by Jun‐Li Liu, Jaemin Lee, Mario Andrés Salazar Hernández, Ralph Mazitschek, Umut Özcan

    Published 2015
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  4. 4
    Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6

    Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6 by Yuliya Zilberman, Christoph Ballestrem, Letizia Carramusa, Ralph Mazitschek, Saadi Khochbin, Alexander D. Bershadsky

    Published 2009
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  5. 5
    In Vivo PET Imaging of Histone Deacetylases by <sup>18</sup>F-Suberoylanilide Hydroxamic Acid (<sup>18</sup>F-SAHA)

    In Vivo PET Imaging of Histone Deacetylases by <sup>18</sup>F-Suberoylanilide Hydroxamic Acid (<sup>18</sup>F-SAHA) by J. Adam Hendricks, Edmund J. Keliher, Brett Marinelli, Thomas Reiner, Ralph Weissleder, Ralph Mazitschek

    Published 2011
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  6. 6
    On the inhibition of histone deacetylase 8

    On the inhibition of histone deacetylase 8 by Guillermina Estiú, Nathan West, Ralph Mazitschek, Edward F. Greenberg, James E. Bradner, Olaf Wiest

    Published 2010
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  7. 7
    In vivo imaging of specific drug–target binding at subcellular resolution

    In vivo imaging of specific drug–target binding at subcellular resolution by J. Matthew Dubach, Claudio Vinegoni, Ralph Mazitschek, Paolo Fumene Feruglio, Lisa Cameron, Ralph Weissleder

    Published 2014
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  8. 8
    Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly

    Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly by R.J. Adamson, N. Connor Payne, Sergio G. Bartual, Ralph Mazitschek, Alex N. Bullock

    Published 2023
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  9. 9
    Inhibition of histone deacetylase 6 improves long-term survival in a lethal septic model

    Inhibition of histone deacetylase 6 improves long-term survival in a lethal septic model by Yongqing Li, Ting Zhao, Baoling Liu, Ihab Halaweish, Ralph Mazitschek, Xiuzhen Duan, Hasan B. Alam

    Published 2015
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  10. 10
    Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells

    Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells by Jonathan Iaconelli, Jasmin Lalonde, Bradley Watmuff, Bangyan Liu, Ralph Mazitschek, Stephen J. Haggarty, Rakesh Karmacharya

    Published 2017
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  11. 11
    Characterization of indolinones which preferentially inhibit VEGF‐C‐ and VEGF‐D‐induced activation of VEGFR‐3 rather than VEGFR‐2

    Characterization of indolinones which preferentially inhibit VEGF‐C‐ and VEGF‐D‐induced activation of VEGFR‐3 rather than VEGFR‐2 by Vladimir Kirkin, Ralph Mazitschek, Jaya Krishnan, Anja Steffen, Johannes Waltenberger, Michael S. Pepper, Athanassios Giannis, Jonathan P. Sleeman

    Published 2001
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  12. 12
    Chemical phylogenetics of histone deacetylases

    Chemical phylogenetics of histone deacetylases by James E. Bradner, Nathan West, Melissa L. Grachan, Edward F. Greenberg, Stephen J. Haggarty, Tandy Warnow, Ralph Mazitschek

    Published 2010
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  13. 13
    HDAC3 regulates DNMT1 expression in multiple myeloma: therapeutic implications

    HDAC3 regulates DNMT1 expression in multiple myeloma: therapeutic implications by Takeshi Harada, Hiroto Ohguchi, Yohann Grondin, Shohei Kikuchi, M. Sagawa, YT Tai, Ralph Mazitschek, Teru Hideshima, Kenneth C. Anderson

    Published 2017
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  14. 14
    A Singular System with Precise Dosing and Spatiotemporal Control of CRISPR‐Cas9

    A Singular System with Precise Dosing and Spatiotemporal Control of CRISPR‐Cas9 by Debasish Manna, Basudeb Maji, Soumyashree A. Gangopadhyay, Kurt J. Cox, Qingxuan Zhou, Benjamin K. Law, Ralph Mazitschek, Amit Choudhary

    Published 2019
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  15. 15
    Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models

    Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models by Pengyu Huang, Ingrid Almeciga-Pinto, Matthew Jarpe, John H. van Duzer, Ralph Mazitschek, Min Yang, Simon S. Jones, Steven N. Quayle

    Published 2016
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  16. 16
    Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

    Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation by Natsumi Ageta‐Ishihara, Takaki Miyata, Chika Ohshima, Masahiko Watanabe, Yoshikatsu Sato, Yuki Hamamura, Tetsuya Higashiyama, Ralph Mazitschek, Haruhiko Bito, Makoto Kinoshita

    Published 2013
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  17. 17
    Antidepressant-Like Properties of Novel HDAC6-Selective Inhibitors with Improved Brain Bioavailability

    Antidepressant-Like Properties of Novel HDAC6-Selective Inhibitors with Improved Brain Bioavailability by Jeanine Jochems, Janette Boulden, Bridgin G. Lee, Julie A. Blendy, Matthew Jarpe, Ralph Mazitschek, John H. van Duzer, Simon Jones, Olivier Berton

    Published 2013
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  18. 18
    Synapse microarray identification of small molecules that enhance synaptogenesis

    Synapse microarray identification of small molecules that enhance synaptogenesis by Peng Shi, Mark A. Skylar‐Scott, Balaram Ghosh, Dongpeng Wan, Zachary D. Wissner-Gross, Ralph Mazitschek, Stephen J. Haggarty, Mehmet Fatih Yanik

    Published 2011
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  19. 19
    HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy

    HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy by Karen Krukowski, Jiacheng Ma, Olga Golonzhka, Geoffroy Laumet, T. Gutti, John H. van Duzer, Ralph Mazitschek, Matthew Jarpe, Cobi J. Heijnen, Annemieke Kavelaars

    Published 2017
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  20. 20
    The cyclimids: Degron-inspired cereblon binders for targeted protein degradation

    The cyclimids: Degron-inspired cereblon binders for targeted protein degradation by Saki Ichikawa, N. Connor Payne, Wenqing Xu, Chia‐Fu Chang, Nandini Vallavoju, Spencer Frome, Hope A. Flaxman, Ralph Mazitschek, Christina M. Woo

    Published 2024
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