Search Results - Rajesh Ambasudhan

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  1. 1
    Direct lineage reprogramming to neural cells

    Direct lineage reprogramming to neural cells by Janghwan Kim, Rajesh Ambasudhan, Sheng Ding

    Published 2012
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  2. 2
    Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell–derived neural progenitor cells

    Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell–derived neural progenitor cells by Rajesh Ambasudhan, Nima Dolatabadi, Anthony Nutter, Eliezer Masliah, Scott R. McKercher, Stuart A. Lipton

    Published 2014
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  3. 3
    Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions

    Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions by Rajesh Ambasudhan, Maria Talantova, R.L. Coleman, Yuan Xu, Saiyong Zhu, Stuart A. Lipton, Sheng Ding

    Published 2011
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  4. 4
    Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds

    Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds by Saiyong Zhu, Wenlin Li, Hongyan Zhou, Wanguo Wei, Rajesh Ambasudhan, Tongxiang Lin, Janghwan Kim, Kang Zhang, Sheng Ding

    Published 2010
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  5. 5
    Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls

    Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls by Swagata Ghatak, Nima Dolatabadi, Dorit Trudler, Xiaotong Zhang, Yin Wu, Madhav Mohata, Rajesh Ambasudhan, Maria Talantova, Stuart A. Lipton

    Published 2019
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  6. 6
    A chemical platform for improved induction of human iPSCs

    A chemical platform for improved induction of human iPSCs by Tongxiang Lin, Rajesh Ambasudhan, Yuan Xu, Wenlin Li, Simon Hilcove, Ramzey Abujarour, Xiangyi Lin, Heung Sik Hahm, Ergeng Hao, Alberto Hayek, Sheng Ding

    Published 2009
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  7. 7
    Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease

    Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease by Aman P. Mann, Pablo Scodeller, Sazid Hussain, Gary B. Braun, Tarmo Mölder, Kadri Toome, Rajesh Ambasudhan, Tambet Teesalu, Stuart A. Lipton, Erkki Ruoslahti

    Published 2017
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  8. 8
    Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases

    Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases by Tomohiro Nakamura, Olga Prikhodko, Elaine Pirie, Saumya Nagar, Mohd Waseem Akhtar, Chang-ki Oh, Scott R. McKercher, Rajesh Ambasudhan, Shu‐ichi Okamoto, Stuart A. Lipton

    Published 2015
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  9. 9
    Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation

    Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation by Mohd Waseem Akhtar, Sara Sanz‐Blasco, Nima Dolatabadi, James Parker, Kevin Chon, Michelle S. Lee, Walid Soussou, Scott R. McKercher, Rajesh Ambasudhan, Tomohiro Nakamura, Stuart A. Lipton

    Published 2016
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  10. 10
    Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons

    Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons by Carmen R. Sunico, Abdullah Sultan, Tomohiro Nakamura, Nima Dolatabadi, James Parker, Bing Shan, Xuemei Han, John R. Yates, Eliezer Masliah, Rajesh Ambasudhan, Nobuki Nakanishi, Stuart A. Lipton

    Published 2016
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  11. 11
    NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models

    NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models by Swagata Ghatak, Nima Dolatabadi, Richard Gao, Yin Wu, Henry Scott, Dorit Trudler, Abdullah Sultan, Rajesh Ambasudhan, Tomohiro Nakamura, Eliezer Masliah, Maria Talantova, Bradley Voytek, Stuart A. Lipton

    Published 2020
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  12. 12
    Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein

    Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein by Tammy Ryan, Vladimir V. Bamm, Morgan G. Stykel, Carla Coackley, Kayla Humphries, Rhiannon Jamieson-Williams, Rajesh Ambasudhan, Dick D. Mosser, Stuart A. Lipton, George Harauz, Scott D. Ryan

    Published 2018
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  13. 13
    Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

    Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors by Wenlin Li, Woong Sun, Yu Zhang, Wanguo Wei, Rajesh Ambasudhan, Peng Xia, Maria Talantova, Tongxiang Lin, Janghwan Kim, Xiaolei Wang, Woon Ryoung Kim, Stuart A. Lipton, Kang Zhang, Sheng Ding

    Published 2011
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  14. 14
    S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models

    S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models by Chang-ki Oh, Abdullah Sultan, Joseph Platzer, Nima Dolatabadi, Frank Soldner, Daniel B. McClatchy, Jolene K. Diedrich, John R. Yates, Rajesh Ambasudhan, Tomohiro Nakamura, Rudolf Jaenisch, Stuart A. Lipton

    Published 2017
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  15. 15
    Hydrogen Sulfide—Mechanisms of Toxicity and Development of an Antidote

    Hydrogen Sulfide—Mechanisms of Toxicity and Development of an Antidote by Jingjing Jiang, Adriano Chan, Sameh S. Ali, Arindam Saha, Kristofer J. Haushalter, Wai-Ling Macrina Lam, Megan Glasheen, James Parker, Matthew Brenner, Sari Mahon, Hemal H. Patel, Rajesh Ambasudhan, Stuart A. Lipton, Renate B. Pilz, Gerry R. Boss

    Published 2016
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  16. 16
    Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia

    Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia by Dorit Trudler, Kristopher L. Nazor, Yvonne S. Eisele, Titas Grabauskas, Nima Dolatabadi, James Parker, Abdullah Sultan, Zhenyu Zhong, Marshall S. Goodwin, Yona Levites, Todd E. Golde, Jeffery W. Kelly, Michael R. Sierks, Nicholas J. Schork, Michael Karin, Rajesh Ambasudhan, Stuart A. Lipton

    Published 2021
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  17. 17
    Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells

    Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells by Saiyong Zhu, Rajesh Ambasudhan, Woong Sun, Hyun Jung Kim, Maria Talantova, Xiaojing Wang, Mingliang Zhang, Yu Zhang, Timothy Laurent, James Parker, Han-Seop Kim, Jeffrey D. Zaremba, Sofiyan Saleem, Sara Sanz‐Blasco, Eliezer Masliah, Scott R. McKercher, Yee Sook Cho, Stuart A. Lipton, Janghwan Kim, Sheng Ding

    Published 2013
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  18. 18
    Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription

    Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription by Scott D. Ryan, Nima Dolatabadi, Shing Fai Chan, Xiaofei Zhang, Mohd Waseem Akhtar, James Parker, Frank Soldner, Carmen R. Sunico, Saumya Nagar, Maria Talantova, Brian Lee, Kevin Lopez, Anthony Nutter, Bing Shan, Elena Molokanova, Yaoyang Zhang, Xuemei Han, Tomohiro Nakamura, Eliezer Masliah, John R. Yates, Nobuki Nakanishi, Alexander Y. Andreyev, Shu‐ichi Okamoto, Rudolf Jaenisch, Rajesh Ambasudhan, Stuart A. Lipton

    Published 2013
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  19. 19
    NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism

    NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism by Shichun Tu, Mohd Waseem Akhtar, Rosa M. Escorihuela, Alejandro Amador‐Arjona, Vivek Swarup, James Parker, Jeffrey D. Zaremba, Timothy Holland, Neha Bansal, Daniel R. Holohan, Kevin Lopez, Scott D. Ryan, Shing Fai Chan, Li Yan, Xiaofei Zhang, Xiayu Huang, Abdullah Sultan, Scott R. McKercher, Rajesh Ambasudhan, Huaxi Xu, Yuqiang Wang, Daniel H. Geschwind, Amanda J. Roberts, Alexey V. Terskikh, Robert A. Rissman, Eliezer Masliah, Stuart A. Lipton, Nobuki Nakanishi

    Published 2017
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  20. 20
    Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

    Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss by Maria Talantova, Sara Sanz‐Blasco, Xiaofei Zhang, Peng Xia, Mohd Waseem Akhtar, Shu‐ichi Okamoto, Gustavo Dziewczapolski, Tomohiro Nakamura, Gang Cao, Alexander E. Pratt, Yeon‐Joo Kang, Shichun Tu, Elena Molokanova, Scott R. McKercher, Samuel Andrew Hires, Hagit Sason, David G. Stouffer, Matthew W. Buczynski, James P. Solomon, Sarah Michael, Evan T. Powers, Jeffery W. Kelly, Amanda J. Roberts, Gary Tong, Traci Fang-Newmeyer, James Parker, Emily A. Holland, Dongxian Zhang, Nobuki Nakanishi, H.-S. Vincent Chen, Herman Wolosker, Yuqiang Wang, Loren H. Parsons, Rajesh Ambasudhan, Eliezer Masliah, Stephen F. Heinemann, Juan Piña-Crespo, Stuart A. Lipton

    Published 2013
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