Результаты поиска - Rajat M. Gupta

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  1. 1
    The Role of Endothelial Cells in Atherosclerosis

    The Role of Endothelial Cells in Atherosclerosis по Mark E. Pepin, Rajat M. Gupta

    Опубликовано 2023
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  2. 2
    HiDDEN: a machine learning method for detection of disease-relevant populations in case-control single-cell transcriptomics data

    HiDDEN: a machine learning method for detection of disease-relevant populations in case-control single-cell transcriptomics data по Aleksandrina Goeva, Michael-John Dolan, Judy Luu, Éric Garcia, Rebecca Boiarsky, Rajat M. Gupta, Evan Z. Macosko

    Опубликовано 2024
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    Artigo
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  3. 3
    Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association

    Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association по Kiran Musunuru, Farah Sheikh, Rajat M. Gupta, Steven R. Houser, Kevin Maher, David J. Milan, André Terzic, Joseph C. Wu

    Опубликовано 2018
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  4. 4
    Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations

    Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations по Aditya S. Kalluri, Shamsudheen Karuthedath Vellarikkal, Elazer R. Edelman, Lan Nguyễn, Ayshwarya Subramanian, Patrick T. Ellinor, Aviv Regev, Sekar Kathiresan, Rajat M. Gupta

    Опубликовано 2019
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    Artigo
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  5. 5
    Impaired Regulatory T-Cell Response and Enhanced Atherosclerosis in the Absence of Inducible Costimulatory Molecule

    Impaired Regulatory T-Cell Response and Enhanced Atherosclerosis in the Absence of Inducible Costimulatory Molecule по Israel Gotsman, Nir Grabie, Rajat M. Gupta, Rosa DaCosta, Malcolm MacConmara, James A. Lederer, Galina K. Sukhova, Joseph L. Witztum, Arlene H. Sharpe, Andrew H. Lichtman

    Опубликовано 2006
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    Artigo
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  6. 6
    Myocardial Infarction–Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With <i>PHACTR1</i> Expression Levels in Human Coronary Arteries

    Myocardial Infarction–Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With <i>PHACTR1</i> Expression Levels in Human Coronary Arteries по Mélissa Beaudoin, Rajat M. Gupta, Hong‐Hee Won, Ken Sin Lo, Ron Do, Christopher A. Henderson, Claire Lavoie-St-Amour, Simon Langlois, Daniel Rivas, Stéphanie Lehoux, Sekar Kathiresan, Jean‐Claude Tardif, Yan V. Sun, Guillaume Lettre

    Опубликовано 2015
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    Artigo
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  7. 7
    Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease

    Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease по Qiuyu Zhu, Yu-Han H. Hsu, Frederik H. Lassen, Bryan T. MacDonald, S. Matthew Stead, Edyta Małolepsza, April Kim, Taibo Li, Taiji Mizoguchi, Monica Schenone, Gaelen Guzman, Benjamin Tanenbaum, Nadine Fornelos, Steven A. Carr, Rajat M. Gupta, Patrick T. Ellinor, Kasper Lage

    Опубликовано 2024
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    Artigo
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  8. 8
    Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis

    Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis по J. Travis Hinson, Anant Chopra, Andre Lowe, Calvin C. Sheng, Rajat M. Gupta, Kuppusamy Rajarajan, John O’Sullivan, Glenn C. Rowe, Hiroko Wakimoto, Joshua M. Gorham, Michael A. Burke, Kehan Zhang, Kiran Musunuru, Robert E. Gerszten, Sean M. Wu, Christopher S. Chen, Jonathan G. Seidman, Christine E. Seidman

    Опубликовано 2016
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    Artigo
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  9. 9
    A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression

    A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression по Rajat M. Gupta, Joseph Hadaya, Aditi Trehan, Seyedeh M. Zekavat, Carolina Roselli, Derek Klarin, Connor A. Emdin, Catharina R.E. Hilvering, Valerio Bianchi, Christian Mueller, Amit V. Khera, Russell J.H. Ryan, J Engreitz, Robbyn Issner, Noam Shoresh, Charles B. Epstein, Wouter de Laat, Jonathan D. Brown, Renate B. Schnabel, B Bernstein, Sekar Kathiresan

    Опубликовано 2017
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    Artigo
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  10. 10
    Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

    Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases по E. Weeks, Jacob C. Ulirsch, Nathan Cheng, Brian L. Trippe, Rebecca S. Fine, Jenkai Miao, Tejal A. Patwardhan, Masahiro Kanai, Joseph Nasser, Charles P. Fulco, Katherine Tashman, François Aguet, Taibo Li, José Ordovás-Montañés, Christopher S. Smillie, Moshe Biton, Alex K. Shalek, Ashwin N. Ananthakrishnan, Ramnik J. Xavier, Aviv Regev, Rajat M. Gupta, Kasper Lage, Kristin Ardlie, Joel N. Hirschhorn, Eric S. Lander, J Engreitz, Hilary K. Finucane

    Опубликовано 2020
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  11. 11
    Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

    Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases по E. Weeks, Jacob C. Ulirsch, Nathan Cheng, Brian L. Trippe, Rebecca S. Fine, Jenkai Miao, Tejal A. Patwardhan, Masahiro Kanai, Joseph Nasser, Charles P. Fulco, Katherine Tashman, François Aguet, Taibo Li, José Ordovás-Montañés, Christopher S. Smillie, Moshe Biton, Alex K. Shalek, Ashwin N. Ananthakrishnan, Ramnik J. Xavier, Aviv Regev, Rajat M. Gupta, Kasper Lage, Kristin Ardlie, Joel N. Hirschhorn, Eric S. Lander, J Engreitz, Hilary K. Finucane

    Опубликовано 2023
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    Artigo
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  12. 12
    Convergence of coronary artery disease genes onto endothelial cell programs

    Convergence of coronary artery disease genes onto endothelial cell programs по Gavin R. Schnitzler, Helen Y. Kang, Shi Fang, Ramcharan Singh Angom, Vivian S. Lee, X. Rosa, Ronghao Zhou, Tony Zeng, Katherine Guo, Martin S. Taylor, Shamsudheen Karuthedath Vellarikkal, Aurelie Barry, Oscar Sias‐Garcia, Alex Bloemendal, Glen Munson, Philine Guckelberger, Tung H. Nguyen, Drew T. Bergman, Stephen M. Hinshaw, Nathan Cheng, Brian Cleary, Krishna G. Aragam, Eric S. Lander, Hilary K. Finucane, Debabrata Mukhopadhyay, Rajat M. Gupta, J Engreitz

    Опубликовано 2024
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  13. 13
    Deep learning enables genetic analysis of the human thoracic aorta

    Deep learning enables genetic analysis of the human thoracic aorta по James P. Pirruccello, Mark Chaffin, Elizabeth L. Chou, Stephen J. Fleming, Honghuang Lin, Mahan Nekoui, Shaan Khurshid, Samuel Friedman, Alexander G. Bick, Alessandro Arduini, Lu‐Chen Weng, Seung Hoan Choi, Amer-Denis Akkad, Puneet Batra, Nathan R. Tucker, Amelia Weber Hall, Carolina Roselli, Emelia J. Benjamin, Shamsudheen Karuthedath Vellarikkal, Rajat M. Gupta, Christian M. Stegmann, Dejan Juric, James R. Stone, Ramachandran S. Vasan, Jennifer E. Ho, Udo Hoffmann, Steven A. Lubitz, Anthony Philippakis, Mark E. Lindsay, Patrick T. Ellinor

    Опубликовано 2021
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  14. 14
    Polygenic prediction of preeclampsia and gestational hypertension

    Polygenic prediction of preeclampsia and gestational hypertension по Michael C. Honigberg, Buu Truong, Raiyan R. Khan, Brenda Xiao, Laxmi Bhatta, Ha My T. Vy, Rafael F. Guerrero, Art Schuermans, Margaret Sunitha Selvaraj, Aniruddh P. Patel, Satoshi Koyama, So Mi Jemma Cho, Shamsudheen Karuthedath Vellarikkal, Mark Trinder, Sarah Urbut, Kathryn J. Gray, Ben Brumpton, Snehal Patil, Sebastian Zöllner, Mariah C. Antopia, Richa Saxena, Girish N. Nadkarni, Ron Do, Qi Yan, Itsik Pe’er, Shefali S. Verma, Rajat M. Gupta, David M. Haas, Hilary C. Martin, David A. van Heel, Triin Laisk, Pradeep Natarajan

    Опубликовано 2023
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  15. 15
    Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

    Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants по Krishna G. Aragam, Tao Jiang, Anuj Goel, Stavroula Kanoni, Brooke N. Wolford, Deepak Atri, E. Weeks, Minxian Wang, George Hindy, Wei Zhou, Christopher Grace, Carolina Roselli, Nicholas Marston, Frederick Kamanu, Ida Surakka, Loreto Muñoz Venegas, Paul Sherliker, Satoshi Koyama, Kazuyoshi Ishigaki, Bjørn Olav Åsvold, Michael R. Brown, Ben Brumpton, Paul S. de Vries, Olga Giannakopoulou, Tota Giardoglou, Daníel F. Guðbjartsson, Ulrich Güldener, Syed M. Ijlal Haider, Anna Helgadóttir, M Ibrahim, Adnan Kastrati, Thorsten Kessler, Theodosios Kyriakou, Tomasz Konopka, Ling Li, Lijiang Ma, Thomas Meitinger, Sören Mucha, Matthias Munz, Federico Murgia, Jonas B. Nielsen, Markus M. Nöthen, Shichao Pang, Tobias Reinberger, Gavin R. Schnitzler, Damian Smedley, Guðmar Þorleifsson, Moritz von Scheidt, Jacob C. Ulirsch, John Danesh, Davíð O. Arnar, Noël P. Burtt, Maria C. Costanzo, Jason Flannick, Kaoru Ito, Dongkeun Jang, Yoichiro Kamatani, Amit V. Khera, Issei Komuro, Iftikhar J. Kullo, Luca A. Lotta, Christopher P. Nelson, Robert Roberts, Guðmundur Þorgeirsson, Unnur Þorsteinsdóttir, Tom R. Webb, Aris Baras, Johan Björkegren, Eric Boerwinkle, George Dedoussis, Hilma Hólm, Kristian Hveem, Olle Melander, Alanna C. Morrison, Marju Orho‐Melander, Lοukianos S. Rallidis, Arno Ruusalepp, Marc S. Sabatine, Kāri Stefánsson, Pierre Zalloua, Patrick T. Ellinor, Martin Farrall, John Danesh, Christian T. Ruff, Hilary K. Finucane, Jemma C. Hopewell, Robert Clarke, Rajat M. Gupta, Jeanette Erdmann, Nilesh J. Samani, Heribert Schunkert, Hugh Watkins, Cristen J. Willer, Panos Deloukas, Sekar Kathiresan, Adam S. Butterworth, Paul S. de Vries, Moritz von Scheidt

    Опубликовано 2022
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  16. 16
    A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

    A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2 по Toni Delorey, Carly G.K. Ziegler, Graham Heimberg, Rachelly Normand, Yiming Yang, Åsa Segerstolpe, Domenic Abbondanza, Stephen J. Fleming, Ayshwarya Subramanian, Daniel T. Montoro, Karthik A. Jagadeesh, Kushal K. Dey, Pritha Sen, Michal Slyper, Yered Pita-Juárez, Devan Phillips, Zohar Bloom-Ackerman, Nick Barkas, Andrea Ganna, James Gomez, Erica Normandin, Pourya Naderi Yeganeh, Yury Popov, Siddharth S. Raju, Sebastian Niezen, Linus Tsai, Katherine J. Siddle, Malika Sud, Victoria M. Tran, Shamsudheen Karuthedath Vellarikkal, Liat Amir-Zilberstein, Deepak Atri, Joseph Beechem, Olga R. Brook, Jonathan H. Chen, Prajan Divakar, Phylicia Dorceus, J Engreitz, Adam L. Essene, Donna M. Fitzgerald, Robin Fropf, Steven Gazal, Joshua Gould, John Grzyb, Tyler Harvey, Jonathan L. Hecht, Tyler Hether, Judit Jané‐Valbuena, Michael Leney-Greene, Hui Ma, Cristin McCabe, Daniel E. McLoughlin, Eric Miller, Christoph Muus, Mari Niemi, Robert F. Padera, Liuliu Pan, Deepti Pant, Carmel Pe’er, Jenna Pfiffner-Borges, Christopher J. Pinto, Jacob Plaisted, Jason Reeves, Marty Ross, Melissa A. Rudy, Erroll H. Rueckert, Michelle Siciliano, Alexander Sturm, Ellen Todres, Avinash Waghray, Sarah Warren, Shuting Zhang, Daniel R. Zollinger, Lisa A. Cosimi, Rajat M. Gupta, Nir Hacohen, Yoshihide Hayashizaki, Alkes L. Price, Jayaraj Rajagopal, Purushothama Rao Tata, Stefan Riedel, Gyöngyi Szabó, Timothy L. Tickle, Deborah T. Hung, Pardis C. Sabeti, Richard Novák, Robert Rogers, Donald E. Ingber, Z. Gordon Jiang, Dejan Juric, Mehrtash Babadi, Samouil L. Farhi, James R. Stone, Ioannis S. Vlachos, Isaac H. Solomon, Orr Ashenberg, Caroline Porter, Bo Li, Alex K. Shalek, Alexandra–Chloé Villani

    Опубликовано 2021
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  17. 17
    COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

    COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets по Toni Delorey, Carly G.K. Ziegler, Graham Heimberg, Rachelly Normand, Yiming Yang, Åsa Segerstolpe, Domenic Abbondanza, Stephen J. Fleming, Ayshwarya Subramanian, Daniel T. Montoro, Karthik A. Jagadeesh, Kushal K. Dey, Pritha Sen, Michal Slyper, Yered Pita-Juárez, Devan Phillips, Jana Biermann, Zohar Bloom‐Ackermann, Nikolaos Barkas, Andrea Ganna, James Gomez, Johannes C. Melms, Igor Katsyv, Erica Normandin, Pourya Naderi Yeganeh, Yury Popov, Siddharth S. Raju, Sebastian Niezen, Linus Tsai, Katherine J. Siddle, Malika Sud, Victoria M. Tran, Shamsudheen Karuthedath Vellarikkal, Yiping Wang, Liat Amir-Zilberstein, Deepak Atri, Joseph Beechem, Olga R. Brook, Jonathan H. Chen, Prajan Divakar, Phylicia Dorceus, J Engreitz, Adam L. Essene, Donna M. Fitzgerald, Robin Fropf, Steven Gazal, Joshua Gould, John Grzyb, Tyler Harvey, Jonathan L. Hecht, Tyler Hether, Judit Jané‐Valbuena, Michael Leney-Greene, Hui Ma, Cristin McCabe, Daniel E. McLoughlin, Eric Miller, Christoph Muus, Mari Niemi, Robert F. Padera, Liuliu Pan, Deepti Pant, Carmel Pe’er, Jenna Pfiffner-Borges, Christopher J. Pinto, Jacob Plaisted, Jason Reeves, Marty Ross, Melissa A. Rudy, Erroll H. Rueckert, Michelle Siciliano, Alexander Sturm, Ellen Todres, Avinash Waghray, Sarah Warren, Shuting Zhang, Daniel R. Zollinger, Lisa A. Cosimi, Rajat M. Gupta, Nir Hacohen, Hanina Hibshoosh, Yoshihide Hayashizaki, Alkes L. Price, Jayaraj Rajagopal, Purushothama Rao Tata, Stefan Riedel, Gyöngyi Szabó, Timothy L. Tickle, Patrick T. Ellinor, Deborah T. Hung, Pardis C. Sabeti, Richard Novák, Robert Rogers, Donald E. Ingber, Z. Gordon Jiang, Dejan Juric, Mehrtash Babadi, Samouil L. Farhi, Benjamin Izar, James R. Stone

    Опубликовано 2021
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