Search Results - Radim Nencka

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  1. 1
    Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses

    Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses by Luděk Eyer, Radim Nencka, Erik De Clercq, Katherine L. Seley‐Radtke, Daniel Růžek

    Published 2018
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  2. 2
    Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses

    Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses by Eva Konkoľová, Milan Dejmek, Hubert Hřebabecký, Michal Šála, Jiří Böserle, Radim Nencka, Evžen Bouřa

    Published 2020
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  3. 3
    Coronaviral RNA-methyltransferases: function, structure and inhibition

    Coronaviral RNA-methyltransferases: function, structure and inhibition by Radim Nencka, Jan Šilhán, Martin Klíma, Tomáš Otava, Hugo Kocek, Petra Krafčíková, Evžen Bouřa

    Published 2021
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  4. 4
    Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein

    Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein by Dhurvas Chandrasekaran Dinesh, Dominika Chalupská, Jan Šilhán, Eliška Koutná, Radim Nencka, Václav Veverka, Evžen Bouřa

    Published 2020
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  5. 5
    Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase

    Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase by Jan Šilhán, Martin Klíma, Tomáš Otava, Petr Skvara, Dominika Chalupská, Karel Chalupský, Jan Kozic, Radim Nencka, Evžen Bouřa

    Published 2023
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  6. 6
    Nucleoside Inhibitors of Zika Virus

    Nucleoside Inhibitors of Zika Virus by Luděk Eyer, Radim Nencka, Ivana Huvarová, Martin Palus, Maria João Alves, Ernest A. Gould, Erik De Clercq, Daniel Růžek

    Published 2016
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  7. 7
    The crystal structure of the phosphatidylinositol 4‐kinase <scp>II</scp>α

    The crystal structure of the phosphatidylinositol 4‐kinase <scp>II</scp>α by Adriana Bäumlová, Dominika Chalupská, Bartosz Różycki, Marko Jović, Éva Wisniewski, Martin Klíma, Anna Dubánková, Daniel P. Kloer, Radim Nencka, Tamás Balla, Evžen Bouřa

    Published 2014
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  8. 8
    Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein

    Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein by Miroslav Smola, Ondrej Gutten, Milan Dejmek, Milan Kožíšek, Thomas Evangelidis, Zahra Aliakbar Tehrani, Barbora Novotná, Radim Nencka, Gabriel Birkuš, Lubomı́r Rulı́s̆ek, Evžen Bouřa

    Published 2021
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  9. 9
    Nucleoside Inhibitors of Tick-Borne Encephalitis Virus

    Nucleoside Inhibitors of Tick-Borne Encephalitis Virus by Luděk Eyer, James J. Valdés, V. Gil, Radim Nencka, Hubert Hřebabecký, Michal Šála, Jiřı́ Salát, Jiří Černý, Martin Palus, Erik De Clercq, Daniel Růžek

    Published 2015
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  10. 10
    A novel and potent brain penetrant inhibitor of extracellular vesicle release

    A novel and potent brain penetrant inhibitor of extracellular vesicle release by Camilo Rojas, Michal Šála, Ajit G. Thomas, Amrita Datta Chaudhuri, Seung‐Wan Yoo, Zhigang Li, Ranjeet Prasad Dash, Rana Rais, Norman J. Haughey, Radim Nencka, Barbara S. Slusher

    Published 2019
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  11. 11
    Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein

    Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein by Martin Klíma, Dániel J. Tóth, R. Hexnerova, Adriana Bäumlová, Dominika Chalupská, Jan Tykvart, Lenka Řežábková, Nivedita Sengupta, Petr Man, Anna Dubánková, Jana Humpolíčková, Radim Nencka, Václav Veverka, Tamás Balla, Evžen Bouřa

    Published 2016
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  12. 12
    Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer’s Disease

    Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer’s Disease by Michal Šála, Kristen R. Hollinger, Ajit G. Thomas, Ranjeet Prasad Dash, Carolyn Tallon, Vijayabhaskar Veeravalli, Lyndah Lovell, Martin Kögler, Hubert Hřebabecký, Eliška Procházková, Ondřej Nešuta, Amanda Donoghue, Jenny Lam, Rana Rais, Camilo Rojas, Barbara S. Slusher, Radim Nencka

    Published 2020
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  13. 13
    SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

    SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia by Courtney Chambers, Kateřina Čermáková, Yuen San Chan, Kristen Kurtz, Katharina Wohlan, Andrew Henry Lewis, Christiana Wang, Anh Pham, Milan Dejmek, Michal Šála, Mario Loeza Cabrera, Rogelio Aguilar, Radim Nencka, H. Daniel Lacorazza, Rachel E. Rau, H. Courtney Hodges

    Published 2023
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  14. 14
    The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model

    The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model by Ján Dušek, Ivana Mejdrová, Klára Dohnalová, Tomáš Smutný, Karel Chalupský, Mária Krutáková, Josef Škoda, Azam Rashidian, Ivona Pávková, Kryštof Škach, Jana Hricová, Michaela Chocholoušková, Lucie Smutná, Rajamanikkam Kamaraj, M Hroch, Martin Leníček, Stanislav Mičuda, Dirk Pijnenburg, Rinie van Beuningen, Michal Holčapek, Libor Vı́tek, Magnus Ingelman‐Sundberg, Oliver Burk, Thales Kronenberger, Radim Nencka, Petr Pávek

    Published 2025
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  15. 15
    Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice

    Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice by Raoul De Gasparo, Mattia Pedotti, Luca Simonelli, Petr Nickl, Frauke Muecksch, Irene Cassaniti, Elena Percivalle, Julio C. C. Lorenzi, Federica Mazzola, Davide Magrì, Tereza Michalčíková, Jan Haviernik, Václav Hönig, Blanka Mrázková, Natalie Polakova, Andrea Fořtová, Jolana Turečková, Veronika Iatsiuk, Salvatore Di Girolamo, Martin Palus, Dagmar Zudová, Petr Bednář, Ivana Buková, Filippo Bianchini, Dóra Méhn, Radim Nencka, Petra Straková, Oto Pavliš, Jan Rozman, Sabrina Gioria, José Camilla Sammartino, Federica Giardina, Stefano Gaiarsa, Qiang Pan‐Hammarström, Christopher O. Barnes, Pamela J. Björkman, Luigi Calzolai, Antonio Piralla, Fausto Baldanti, Michel C. Nussenzweig, Paul D. Bieniasz, Théodora Hatziioannou, Jan Procházka, Radislav Sedláček, Davide F. Robbiani, Daniel Růžek, Luca Varani

    Published 2021
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