Sökresultat - Rachel Culp‐Hill

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  1. 1
    Extinguishing the Embers: Targeting AML Metabolism

    Extinguishing the Embers: Targeting AML Metabolism av Rachel Culp‐Hill, Angelo D’Alessandro, Eric M. Pietras

    Publicerad 2020
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  2. 2
    Metabolic effect of alkaline additives and guanosine/gluconate in storage solutions for red blood cells

    Metabolic effect of alkaline additives and guanosine/gluconate in storage solutions for red blood cells av Angelo D’Alessandro, Julie A. Reisz, Rachel Culp‐Hill, Herbert Korsten, Robin van Bruggen, Dirk de Korte

    Publicerad 2018
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  3. 3
    Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2

    Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2 av Rachel Culp‐Hill, Brett M. Stevens, Courtney L. Jones, Shanshan Pei, Monika Dzieciątkowska, Mohammad Minhajuddin, Craig T. Jordan, Angelo D’Alessandro

    Publicerad 2023
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  4. 4
    Transfusional iron overload and intravenous iron infusions modify the mouse gut microbiota similarly to dietary iron

    Transfusional iron overload and intravenous iron infusions modify the mouse gut microbiota similarly to dietary iron av Francesca La Carpia, Bogusław S. Wójczyk, Medini K. Annavajhala, Abdelhadi Rebbaa, Rachel Culp‐Hill, Angelo D’Alessandro, Daniel E. Freedberg, Anne‐Catrin Uhlemann, Eldad A. Hod

    Publicerad 2019
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  5. 5
    Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity

    Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity av Theresa L. Montgomery, Axel Künstner, Josephine J. Kennedy, Qian Fang, Lori Asarian, Rachel Culp‐Hill, Angelo D’Alessandro, Cory Teuscher, Hauke Busch, Dimitry N. Krementsov

    Publicerad 2020
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  6. 6
    A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma

    A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma av Lisa I. Greene, Tullia C. Bruno, Jessica L. Christenson, Angelo D’Alessandro, Rachel Culp‐Hill, Kathleen C. Torkko, Virginia F. Borges, Jill E. Slansky, Jennifer K. Richer

    Publicerad 2018
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  7. 7
    Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II

    Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II av Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Rachel Culp‐Hill, Julie A. Reisz, Shanshan Pei, Annika Gustafson, Nabilah Khan, James DeGregori, Daniel A. Pollyea, Craig T. Jordan

    Publicerad 2019
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  8. 8
    Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice

    Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice av Heather L. Howie, Ariel M. Hay, Karen de Wolski, Hayley R. Waterman, Jenna N. Lebedev, Xiaoyun Fu, Rachel Culp‐Hill, Angelo D’Alessandro, James D. Gorham, M. Ranson, John D. Roback, Peter C. Thomson, James C. Zimring

    Publicerad 2019
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  9. 9
    Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells

    Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells av Julie A. Reisz, Travis Nemkov, Monika Dzieciątkowska, Rachel Culp‐Hill, Davide Stefanoni, Ryan C. Hill, Tatsuro Yoshida, Andrew Dunham, Tamir Kanias, Larry J. Dumont, Michael P. Busch, Elan Eisenmesser, James C. Zimring, Kirk C. Hansen, Angelo D’Alessandro

    Publicerad 2018
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  10. 10
    Short‐term interleukin‐37 treatment improves vascular endothelial function, endurance exercise capacity, and whole‐body glucose metabolism in old mice

    Short‐term interleukin‐37 treatment improves vascular endothelial function, endurance exercise capacity, and whole‐body glucose metabolism in old mice av Dov B. Ballak, Vienna E. Brunt, Zachary J. Sapinsley, Brian P. Ziemba, James J. Richey, Melanie C. Zigler, Lawrence C. Johnson, Rachel A. Gioscia‐Ryan, Rachel Culp‐Hill, Elan Eisenmesser, Angelo D’Alessandro, Charles A. Dinarello, Douglas R. Seals

    Publicerad 2019
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  11. 11
    Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity

    Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity av Angelo D’Alessandro, Xiaoyun Fu, Tamir Kanias, Julie A. Reisz, Rachel Culp‐Hill, Yuelong Guo, Mark T. Gladwin, Grier P. Page, Steven Kleinman, Marion C. Lanteri, Mars Stone, Michael P. Busch, James C. Zimring, For the Recipient Epidemiology and Donor Evaluation Study-III

    Publicerad 2020
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  12. 12
    Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS‐III—Omics

    Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS‐III—Omics av Angelo D’Alessandro, Rachel Culp‐Hill, Julie A. Reisz, Mikayla Anderson, Xiaoyun Fu, Travis Nemkov, Sarah Gehrke, Connie Zheng, Tamir Kanias, Yuelong Guo, Grier P. Page, Mark T. Gladwin, Steve Kleinman, Marion C. Lanteri, Mars Stone, Michael P. Busch, James C. Zimring

    Publicerad 2018
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  13. 13
    Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

    Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells av Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Julie A. Reisz, Rachel Culp‐Hill, Travis Nemkov, Shanshan Pei, Nabilah Khan, Biniam Adane, Haobin Ye, Anna Krug, Dominik Reinhold, Clayton A. Smith, James DeGregori, Daniel A. Pollyea, Craig T. Jordan

    Publicerad 2018
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  14. 14
    Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells

    Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells av Brett M. Stevens, Courtney L. Jones, Daniel A. Pollyea, Rachel Culp‐Hill, Angelo D’Alessandro, Amanda Winters, Anna Krug, Diana Abbott, Madeline Goosman, Shanshan Pei, Haobin Ye, Austin E. Gillen, Michael W. Becker, Michael R. Savona, Clayton A. Smith, Craig T. Jordan

    Publicerad 2020
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  15. 15
    Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

    Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells av Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Julie A. Reisz, Rachel Culp‐Hill, Travis Nemkov, Shanshan Pei, Nabilah Khan, Biniam Adane, Haobin Ye, Anna Krug, Dominik Reinhold, Clayton A. Smith, James DeGregori, Daniel A. Pollyea, Craig T. Jordan

    Publicerad 2019
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  16. 16
    Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia

    Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia av Daniel A. Pollyea, Brett M. Stevens, Courtney L. Jones, Amanda Winters, Shanshan Pei, Mohammad Minhajuddin, Angelo D’Alessandro, Rachel Culp‐Hill, Kent Riemondy, Austin E. Gillen, Jay R. Hesselberth, Diana Abbott, Derek Schatz, Jonathan A. Gutman, Enkhtsetseg Purev, Clayton A. Smith, Craig T. Jordan

    Publicerad 2018
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  17. 17
    The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells

    The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells av Tamilla Nechiporuk, Stephen E. Kurtz, Olga Nikolova, Tingting Liu, Courtney L. Jones, Angelo D’Alessandro, Rachel Culp‐Hill, Amanda d’Almeida, Sunil K. Joshi, Mara Rosenberg, Cristina E. Tognon, Alexey V. Danilov, Brian J. Druker, Bill H. Chang, Shannon K. McWeeney, Jeffrey W. Tyner

    Publicerad 2019
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  18. 18
    Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells

    Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells av Courtney L. Jones, Brett M. Stevens, Daniel A. Pollyea, Rachel Culp‐Hill, Julie A. Reisz, Travis Nemkov, Sarah Gehrke, Fabia Gamboni, Anna Krug, Amanda Winters, Shanshan Pei, Annika Gustafson, Haobin Ye, Anagha Inguva, Maria L. Amaya, Mohammad Minhajuddin, Diana Abbott, Michael W. Becker, James DeGregori, Clayton A. Smith, Angelo D’Alessandro, Craig T. Jordan

    Publicerad 2020
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  19. 19
    p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression

    p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression av Sung‐Hwan Moon, Chun‐Hao Huang, Shauna L Houlihan, Kausik Regunath, William A. Freed-Pastor, John P. Morris, Darjus F. Tschaharganeh, Edward R. Kastenhuber, Anthony M. Barsotti, Rachel Culp‐Hill, Wen Xue, Yu-Jui Ho, Timour Baslan, Xiang Li, Allison Mayle, Elisa de Stanchina, Lars Zender, David Tong, Angelo D’Alessandro, Scott W. Lowe, Carol Prives

    Publicerad 2018
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  20. 20
    Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

    Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors av Rani K. Powers, Rachel Culp‐Hill, Michael P. Ludwig, Keith P. Smith, Katherine A. Waugh, Ross Minter, Kathryn D. Tuttle, Hannah C Lewis, Angela L. Rachubinski, Ross E. Granrath, María Carmona‐Iragui, Rebecca B. Wilkerson, Darcy E. Kahn, Molishree Joshi, Alberto Lleó, Rafael Blesa, Juan Fortea, Angelo D’Alessandro, James C. Costello, Kelly D. Sullivan, Joaquı́n M. Espinosa

    Publicerad 2019
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