Resultados da busca - Rachel Culp‐Hill
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Extinguishing the Embers: Targeting AML Metabolism por Rachel Culp‐Hill, Angelo D’Alessandro, Eric M. Pietras
Publicado em 2020Revisão -
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Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2 por Rachel Culp‐Hill, Brett M. Stevens, Courtney L. Jones, Shanshan Pei, Monika Dzieciątkowska, Mohammad Minhajuddin, Craig T. Jordan, Angelo D’Alessandro
Publicado em 2023Artigo -
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Transfusional iron overload and intravenous iron infusions modify the mouse gut microbiota similarly to dietary iron por Francesca La Carpia, Bogusław S. Wójczyk, Medini K. Annavajhala, Abdelhadi Rebbaa, Rachel Culp‐Hill, Angelo D’Alessandro, Daniel E. Freedberg, Anne‐Catrin Uhlemann, Eldad A. Hod
Publicado em 2019Artigo -
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Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity por Theresa L. Montgomery, Axel Künstner, Josephine J. Kennedy, Qian Fang, Lori Asarian, Rachel Culp‐Hill, Angelo D’Alessandro, Cory Teuscher, Hauke Busch, Dimitry N. Krementsov
Publicado em 2020Artigo -
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A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma por Lisa I. Greene, Tullia C. Bruno, Jessica L. Christenson, Angelo D’Alessandro, Rachel Culp‐Hill, Kathleen C. Torkko, Virginia F. Borges, Jill E. Slansky, Jennifer K. Richer
Publicado em 2018Artigo -
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Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II por Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Rachel Culp‐Hill, Julie A. Reisz, Shanshan Pei, Annika Gustafson, Nabilah Khan, James DeGregori, Daniel A. Pollyea, Craig T. Jordan
Publicado em 2019Artigo -
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Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice por Heather L. Howie, Ariel M. Hay, Karen de Wolski, Hayley R. Waterman, Jenna N. Lebedev, Xiaoyun Fu, Rachel Culp‐Hill, Angelo D’Alessandro, James D. Gorham, M. Ranson, John D. Roback, Peter C. Thomson, James C. Zimring
Publicado em 2019Artigo -
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Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells por Julie A. Reisz, Travis Nemkov, Monika Dzieciątkowska, Rachel Culp‐Hill, Davide Stefanoni, Ryan C. Hill, Tatsuro Yoshida, Andrew Dunham, Tamir Kanias, Larry J. Dumont, Michael P. Busch, Elan Eisenmesser, James C. Zimring, Kirk C. Hansen, Angelo D’Alessandro
Publicado em 2018Artigo -
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Short‐term interleukin‐37 treatment improves vascular endothelial function, endurance exercise capacity, and whole‐body glucose metabolism in old mice por Dov B. Ballak, Vienna E. Brunt, Zachary J. Sapinsley, Brian P. Ziemba, James J. Richey, Melanie C. Zigler, Lawrence C. Johnson, Rachel A. Gioscia‐Ryan, Rachel Culp‐Hill, Elan Eisenmesser, Angelo D’Alessandro, Charles A. Dinarello, Douglas R. Seals
Publicado em 2019Artigo -
11
Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity por Angelo D’Alessandro, Xiaoyun Fu, Tamir Kanias, Julie A. Reisz, Rachel Culp‐Hill, Yuelong Guo, Mark T. Gladwin, Grier P. Page, Steven Kleinman, Marion C. Lanteri, Mars Stone, Michael P. Busch, James C. Zimring, For the Recipient Epidemiology and Donor Evaluation Study-III
Publicado em 2020Artigo -
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Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS‐III—Omics por Angelo D’Alessandro, Rachel Culp‐Hill, Julie A. Reisz, Mikayla Anderson, Xiaoyun Fu, Travis Nemkov, Sarah Gehrke, Connie Zheng, Tamir Kanias, Yuelong Guo, Grier P. Page, Mark T. Gladwin, Steve Kleinman, Marion C. Lanteri, Mars Stone, Michael P. Busch, James C. Zimring
Publicado em 2018Artigo -
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Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells por Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Julie A. Reisz, Rachel Culp‐Hill, Travis Nemkov, Shanshan Pei, Nabilah Khan, Biniam Adane, Haobin Ye, Anna Krug, Dominik Reinhold, Clayton A. Smith, James DeGregori, Daniel A. Pollyea, Craig T. Jordan
Publicado em 2018Artigo -
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Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells por Brett M. Stevens, Courtney L. Jones, Daniel A. Pollyea, Rachel Culp‐Hill, Angelo D’Alessandro, Amanda Winters, Anna Krug, Diana Abbott, Madeline Goosman, Shanshan Pei, Haobin Ye, Austin E. Gillen, Michael W. Becker, Michael R. Savona, Clayton A. Smith, Craig T. Jordan
Publicado em 2020Artigo -
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Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells por Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Julie A. Reisz, Rachel Culp‐Hill, Travis Nemkov, Shanshan Pei, Nabilah Khan, Biniam Adane, Haobin Ye, Anna Krug, Dominik Reinhold, Clayton A. Smith, James DeGregori, Daniel A. Pollyea, Craig T. Jordan
Publicado em 2019Artigo -
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Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia por Daniel A. Pollyea, Brett M. Stevens, Courtney L. Jones, Amanda Winters, Shanshan Pei, Mohammad Minhajuddin, Angelo D’Alessandro, Rachel Culp‐Hill, Kent Riemondy, Austin E. Gillen, Jay R. Hesselberth, Diana Abbott, Derek Schatz, Jonathan A. Gutman, Enkhtsetseg Purev, Clayton A. Smith, Craig T. Jordan
Publicado em 2018Artigo -
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The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells por Tamilla Nechiporuk, Stephen E. Kurtz, Olga Nikolova, Tingting Liu, Courtney L. Jones, Angelo D’Alessandro, Rachel Culp‐Hill, Amanda d’Almeida, Sunil K. Joshi, Mara Rosenberg, Cristina E. Tognon, Alexey V. Danilov, Brian J. Druker, Bill H. Chang, Shannon K. McWeeney, Jeffrey W. Tyner
Publicado em 2019Artigo -
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Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells por Courtney L. Jones, Brett M. Stevens, Daniel A. Pollyea, Rachel Culp‐Hill, Julie A. Reisz, Travis Nemkov, Sarah Gehrke, Fabia Gamboni, Anna Krug, Amanda Winters, Shanshan Pei, Annika Gustafson, Haobin Ye, Anagha Inguva, Maria L. Amaya, Mohammad Minhajuddin, Diana Abbott, Michael W. Becker, James DeGregori, Clayton A. Smith, Angelo D’Alessandro, Craig T. Jordan
Publicado em 2020Artigo -
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p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression por Sung‐Hwan Moon, Chun‐Hao Huang, Shauna L Houlihan, Kausik Regunath, William A. Freed-Pastor, John P. Morris, Darjus F. Tschaharganeh, Edward R. Kastenhuber, Anthony M. Barsotti, Rachel Culp‐Hill, Wen Xue, Yu-Jui Ho, Timour Baslan, Xiang Li, Allison Mayle, Elisa de Stanchina, Lars Zender, David Tong, Angelo D’Alessandro, Scott W. Lowe, Carol Prives
Publicado em 2018Artigo -
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Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors por Rani K. Powers, Rachel Culp‐Hill, Michael P. Ludwig, Keith P. Smith, Katherine A. Waugh, Ross Minter, Kathryn D. Tuttle, Hannah C Lewis, Angela L. Rachubinski, Ross E. Granrath, María Carmona‐Iragui, Rebecca B. Wilkerson, Darcy E. Kahn, Molishree Joshi, Alberto Lleó, Rafael Blesa, Juan Fortea, Angelo D’Alessandro, James C. Costello, Kelly D. Sullivan, Joaquı́n M. Espinosa
Publicado em 2019Artigo
Ferramentas de busca:
Assuntos relacionados
Biology
Biochemistry
Cancer research
Medicine
Cell biology
Gene
Chemistry
Genetics
Immunology
Internal medicine
Enzyme
Leukemia
Myeloid leukemia
Stem cell
Gene expression
Amino acid
Azacitidine
DNA methylation
Metabolism
Chronic lymphocytic leukemia
Oxidative phosphorylation
Red blood cell
Venetoclax
Cancer
Hemolysis
Oxidative stress
Pharmacology
Cancer cell
Catabolism
Context (archaeology)