検索結果 - Rachel Culp‐Hill
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Extinguishing the Embers: Targeting AML Metabolism 著者: Rachel Culp‐Hill, Angelo D’Alessandro, Eric M. Pietras
出版事項 2020Revisão -
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Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2 著者: Rachel Culp‐Hill, Brett M. Stevens, Courtney L. Jones, Shanshan Pei, Monika Dzieciątkowska, Mohammad Minhajuddin, Craig T. Jordan, Angelo D’Alessandro
出版事項 2023Artigo -
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Transfusional iron overload and intravenous iron infusions modify the mouse gut microbiota similarly to dietary iron 著者: Francesca La Carpia, Bogusław S. Wójczyk, Medini K. Annavajhala, Abdelhadi Rebbaa, Rachel Culp‐Hill, Angelo D’Alessandro, Daniel E. Freedberg, Anne‐Catrin Uhlemann, Eldad A. Hod
出版事項 2019Artigo -
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A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma 著者: Lisa I. Greene, Tullia C. Bruno, Jessica L. Christenson, Angelo D’Alessandro, Rachel Culp‐Hill, Kathleen C. Torkko, Virginia F. Borges, Jill E. Slansky, Jennifer K. Richer
出版事項 2018Artigo -
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Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II 著者: Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Rachel Culp‐Hill, Julie A. Reisz, Shanshan Pei, Annika Gustafson, Nabilah Khan, James DeGregori, Daniel A. Pollyea, Craig T. Jordan
出版事項 2019Artigo -
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Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice 著者: Heather L. Howie, Ariel M. Hay, Karen de Wolski, Hayley R. Waterman, Jenna N. Lebedev, Xiaoyun Fu, Rachel Culp‐Hill, Angelo D’Alessandro, James D. Gorham, M. Ranson, John D. Roback, Peter C. Thomson, James C. Zimring
出版事項 2019Artigo -
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Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells 著者: Julie A. Reisz, Travis Nemkov, Monika Dzieciątkowska, Rachel Culp‐Hill, Davide Stefanoni, Ryan C. Hill, Tatsuro Yoshida, Andrew Dunham, Tamir Kanias, Larry J. Dumont, Michael P. Busch, Elan Eisenmesser, James C. Zimring, Kirk C. Hansen, Angelo D’Alessandro
出版事項 2018Artigo -
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Short‐term interleukin‐37 treatment improves vascular endothelial function, endurance exercise capacity, and whole‐body glucose metabolism in old mice 著者: Dov B. Ballak, Vienna E. Brunt, Zachary J. Sapinsley, Brian P. Ziemba, James J. Richey, Melanie C. Zigler, Lawrence C. Johnson, Rachel A. Gioscia‐Ryan, Rachel Culp‐Hill, Elan Eisenmesser, Angelo D’Alessandro, Charles A. Dinarello, Douglas R. Seals
出版事項 2019Artigo -
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Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity 著者: Angelo D’Alessandro, Xiaoyun Fu, Tamir Kanias, Julie A. Reisz, Rachel Culp‐Hill, Yuelong Guo, Mark T. Gladwin, Grier P. Page, Steven Kleinman, Marion C. Lanteri, Mars Stone, Michael P. Busch, James C. Zimring, For the Recipient Epidemiology and Donor Evaluation Study-III
出版事項 2020Artigo -
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Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS‐III—Omics 著者: Angelo D’Alessandro, Rachel Culp‐Hill, Julie A. Reisz, Mikayla Anderson, Xiaoyun Fu, Travis Nemkov, Sarah Gehrke, Connie Zheng, Tamir Kanias, Yuelong Guo, Grier P. Page, Mark T. Gladwin, Steve Kleinman, Marion C. Lanteri, Mars Stone, Michael P. Busch, James C. Zimring
出版事項 2018Artigo -
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Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells 著者: Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Julie A. Reisz, Rachel Culp‐Hill, Travis Nemkov, Shanshan Pei, Nabilah Khan, Biniam Adane, Haobin Ye, Anna Krug, Dominik Reinhold, Clayton A. Smith, James DeGregori, Daniel A. Pollyea, Craig T. Jordan
出版事項 2018Artigo -
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Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells 著者: Brett M. Stevens, Courtney L. Jones, Daniel A. Pollyea, Rachel Culp‐Hill, Angelo D’Alessandro, Amanda Winters, Anna Krug, Diana Abbott, Madeline Goosman, Shanshan Pei, Haobin Ye, Austin E. Gillen, Michael W. Becker, Michael R. Savona, Clayton A. Smith, Craig T. Jordan
出版事項 2020Artigo -
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Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells 著者: Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Julie A. Reisz, Rachel Culp‐Hill, Travis Nemkov, Shanshan Pei, Nabilah Khan, Biniam Adane, Haobin Ye, Anna Krug, Dominik Reinhold, Clayton A. Smith, James DeGregori, Daniel A. Pollyea, Craig T. Jordan
出版事項 2019Artigo -
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Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia 著者: Daniel A. Pollyea, Brett M. Stevens, Courtney L. Jones, Amanda Winters, Shanshan Pei, Mohammad Minhajuddin, Angelo D’Alessandro, Rachel Culp‐Hill, Kent Riemondy, Austin E. Gillen, Jay R. Hesselberth, Diana Abbott, Derek Schatz, Jonathan A. Gutman, Enkhtsetseg Purev, Clayton A. Smith, Craig T. Jordan
出版事項 2018Artigo -
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The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition in AML Cells 著者: Tamilla Nechiporuk, Stephen E. Kurtz, Olga Nikolova, Tingting Liu, Courtney L. Jones, Angelo D’Alessandro, Rachel Culp‐Hill, Amanda d’Almeida, Sunil K. Joshi, Mara Rosenberg, Cristina E. Tognon, Alexey V. Danilov, Brian J. Druker, Bill H. Chang, Shannon K. McWeeney, Jeffrey W. Tyner
出版事項 2019Artigo -
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Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells 著者: Courtney L. Jones, Brett M. Stevens, Daniel A. Pollyea, Rachel Culp‐Hill, Julie A. Reisz, Travis Nemkov, Sarah Gehrke, Fabia Gamboni, Anna Krug, Amanda Winters, Shanshan Pei, Annika Gustafson, Haobin Ye, Anagha Inguva, Maria L. Amaya, Mohammad Minhajuddin, Diana Abbott, Michael W. Becker, James DeGregori, Clayton A. Smith, Angelo D’Alessandro, Craig T. Jordan
出版事項 2020Artigo -
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p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression 著者: Sung‐Hwan Moon, Chun‐Hao Huang, Shauna L Houlihan, Kausik Regunath, William A. Freed-Pastor, John P. Morris, Darjus F. Tschaharganeh, Edward R. Kastenhuber, Anthony M. Barsotti, Rachel Culp‐Hill, Wen Xue, Yu-Jui Ho, Timour Baslan, Xiang Li, Allison Mayle, Elisa de Stanchina, Lars Zender, David Tong, Angelo D’Alessandro, Scott W. Lowe, Carol Prives
出版事項 2018Artigo -
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Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors 著者: Rani K. Powers, Rachel Culp‐Hill, Michael P. Ludwig, Keith P. Smith, Katherine A. Waugh, Ross Minter, Kathryn D. Tuttle, Hannah C Lewis, Angela L. Rachubinski, Ross E. Granrath, María Carmona‐Iragui, Rebecca B. Wilkerson, Darcy E. Kahn, Molishree Joshi, Alberto Lleó, Rafael Blesa, Juan Fortea, Angelo D’Alessandro, James C. Costello, Kelly D. Sullivan, Joaquı́n M. Espinosa
出版事項 2019Artigo
関連主題
Biology
Biochemistry
Cancer research
Medicine
Cell biology
Gene
Chemistry
Genetics
Immunology
Internal medicine
Enzyme
Leukemia
Myeloid leukemia
Stem cell
Gene expression
Amino acid
Azacitidine
DNA methylation
Metabolism
Chronic lymphocytic leukemia
Oxidative phosphorylation
Red blood cell
Venetoclax
Cancer
Hemolysis
Oxidative stress
Pharmacology
Cancer cell
Catabolism
Context (archaeology)