Search Results - Quang‐Dé Nguyen

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  1. 1
    Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [ <sup>18</sup> F]-labeled isatin sulfonamide

    Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [ <sup>18</sup> F]-labeled isatin sulfonamide by Quang‐Dé Nguyen, Graham Smith, Matthias Glaser, Meg Perumal, Erik Årstad, Eric O. Aboagye

    Published 2009
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  2. 2
    Temporal and Spatial Evolution of Therapy-Induced Tumor Apoptosis Detected by Caspase-3–Selective Molecular Imaging

    Temporal and Spatial Evolution of Therapy-Induced Tumor Apoptosis Detected by Caspase-3–Selective Molecular Imaging by Quang-Dé Nguyen, Ioannis Lavdas, James Gubbins, Graham Smith, Robin Fortt, Laurence Carroll, Martin A. Graham, Eric O. Aboagye

    Published 2013
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  3. 3
    CXCR4‐Targeted and MMP‐Responsive Iron Oxide Nanoparticles for Enhanced Magnetic Resonance Imaging

    CXCR4‐Targeted and MMP‐Responsive Iron Oxide Nanoparticles for Enhanced Magnetic Resonance Imaging by Juan Gallo, Nazila Kamaly, Ioannis Lavdas, Elizabeth Stevens, Quang‐Dé Nguyen, Marzena Wylezinska‐Arridge, Eric O. Aboagye, Nicholas J. Long

    Published 2014
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  4. 4
    Evaluation of Deuterated 18F- and 11C-Labeled Choline Analogs for Cancer Detection by Positron Emission Tomography

    Evaluation of Deuterated 18F- and 11C-Labeled Choline Analogs for Cancer Detection by Positron Emission Tomography by Timothy H. Witney, Israt S. Alam, David R. Turton, Graham Smith, Laurence Carroll, Diana Bric̆kutė, Frazer Twyman, Quang-Dé Nguyen, Giampaolo Tomasi, Ramla Awais, Eric O. Aboagye

    Published 2012
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  5. 5
    Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase‐2 and EGF receptor signaling

    Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase‐2 and EGF receptor signaling by Sylvie Rodrigues, Elisabeth Van Aken, Saskia Van Bocxlaer, Samir Attoub, Quang‐Dé Nguyen, Erik Bruyneel, Bruce R. Westley, Felicity E. B. May, Lars Thim, Marc Mareel, Christian Gespach, Shahin Emami

    Published 2003
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  6. 6
    The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth

    The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth by Sebastian Trousil, Maciej Kaliszczak, Zachary T. Schug, Quang-Dé Nguyen, Giampaolo Tomasi, Rosy Favicchio, Diana Bric̆kutė, Robin Fortt, Frazer Twyman, Laurence Carroll, Andrew Kalusa, Naveenan Navaratnam, Thomas Adejumo, David Carling, Eyal Gottlieb, Eric O. Aboagye

    Published 2016
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  7. 7
    Mechanism of action of the Aurora kinase inhibitor CCT129202 and <i>in vivo</i> quantification of biological activity

    Mechanism of action of the Aurora kinase inhibitor CCT129202 and <i>in vivo</i> quantification of biological activity by Florence Chan, Chongbo Sun, Meg Perumal, Quang‐Dé Nguyen, Vassilios Bavetsias, Edward McDonald, Vanessa Martins, Nicola E. Wilsher, Florence I. Raynaud, Melanie Valenti, Sue Eccles, Robert te Poele, Paul Workman, Eric O. Aboagye, Spiros Linardopoulos

    Published 2007
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  8. 8
    Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1–Specific VHHs

    Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1–Specific VHHs by Michael Dougan, Jessica R. Ingram, Hee‐Jin Jeong, Munir M. Mosaheb, Patrick T. Bruck, Lestat R. Ali, Novalia Pishesha, Olga Blomberg, Paul Tyler, Mariah M. Servos, Mohammad Rashidian, Quang‐Dé Nguyen, Ulrich H. von Andrian, Hidde L. Ploegh, Stephanie K. Dougan

    Published 2018
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  9. 9
    Preclinical Development of PNT6555, a Boronic Acid–Based, Fibroblast Activation Protein-α (FAP)–Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors

    Preclinical Development of PNT6555, a Boronic Acid–Based, Fibroblast Activation Protein-α (FAP)–Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors by Sarah E. Poplawski, Robin Hallett, Mark H. Dornan, Kyle E. Novakowski, Shuang Pan, Anthony P. Belanger, Quang‐Dé Nguyen, Wengen Wu, Albert Felten, Yuxin Liu, Shin Hye Ahn, Valerie S. Hergott, Barry Jones, Jack H. Lai, Joe A. B. McCann, William W. Bachovchin

    Published 2023
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  10. 10
    Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model

    Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model by Yufei Wang, Jae-Won Cho, Gabriella Kastrunes, Alicia Buck, Cecile Razimbaud, Aedín C. Culhane, Jiusong Sun, David A. Braun, Toni K. Choueiri, Catherine J. Wu, Kristen L. Jones, Quang‐Dé Nguyen, Zhu Zhu, Kevin Wei, Quan Zhu, Sabina Signoretti, Gordon J. Freeman, Martin Hemberg, Wayne A. Marasco

    Published 2024
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  11. 11
    Heterogeneity in Lung <sup>18</sup> FDG Uptake in Pulmonary Arterial Hypertension

    Heterogeneity in Lung <sup>18</sup> FDG Uptake in Pulmonary Arterial Hypertension by Lan Zhao, Ali Ashek, Lei Wang, Wei Fang, Swati Dabral, Olivier Dubois, John Cupitt, Soni Savai Pullamsetti, Emanuele Cotroneo, Hazel A. Jones, Gianpaolo Tomasi, Quang‐Dé Nguyen, Eric O. Aboagye, Mona El‐Bahrawy, Gareth Barnes, Luke Howard, J. Simon R. Gibbs, Willy Gsell, Jianguo He, Martin R. Wilkins

    Published 2013
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  12. 12
    Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer

    Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer by Martin Bakht, Yasutaka Yamada, Sheng‐Yu Ku, Varadha Balaji Venkadakrishnan, Joshua A. Korsen, Teja Kalidindi, Kei Mizuno, Shin Hye Ahn, Ji-Heui Seo, Maria Mica Garcia, Francesca Khani, Olivier Elemento, Henry W. Long, Alain Chaglassian, Nagavarakishore Pillarsetty, Jason S. Lewis, Matthew L. Freedman, Anthony P. Belanger, Quang‐Dé Nguyen, Himisha Beltran

    Published 2023
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  13. 13
    Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

    Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG by Jamie N. Anastas, Barry M. Zee, Jay H. Kalin, Mirhee Kim, Robyn Guo, Sanda Alexandrescu, Andrés Blanco, Stefanie Giera, Shawn Gillespie, Jayanta Das, Muzhou Wu, Sarah E. Nocco, Dennis M. Bonal, Quang‐Dé Nguyen, Mario L. Suvà, B Bernstein, Rhoda M. Alani, Todd R. Golub, Philip A. Cole, Mariella G. Filbin, Yang Shi

    Published 2019
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  14. 14
    The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis

    The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis by Matthew G. Oser, Amin H. Sabet, Wenhua Gao, Abhishek A. Chakraborty, Anna C. Schinzel, Rebecca B. Jennings, Raquel Fonseca, Dennis M. Bonal, Matthew A. Booker, Abdallah Flaifel, Jesse Novak, Camilla L. Christensen, Hua Zhang, Zachary T. Herbert, Michael Tolstorukov, Elizabeth Buss, Kwok‐Kin Wong, Roderick T. Bronson, Quang‐Dé Nguyen, Sabina Signoretti, William G. Kaelin

    Published 2019
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  15. 15
    Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1

    Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1 by Yixiang Li, Navin R. Mahadevan, Leslie Duplaquet, Deli Hong, Yavuz T. Durmaz, Kristen L. Jones, Hyeonseo Cho, Murry Morrow, Andrea Protti, Michael J. Poitras, Benjamin F. Springer, Roderick T. Bronson, Xueqian Gong, Yu‐Hua Hui, Jian Du, Jackson Southard, Tran C. Thai, Shuqiang Li, Patrick H. Lizotte, Prafulla C. Gokhale, Quang‐Dé Nguyen, Matthew G. Oser

    Published 2023
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  16. 16
    Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

    Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents by Chen Lossos, Yunpeng Liu, Kellie E. Kolb, Amanda L. Christie, Alexandria Van Scoyk, Sanjay M. Prakadan, Kay Shigemori, Kristen E. Stevenson, Sara Morrow, Olivia D. Plana, Cameron Fraser, Kristen L. Jones, Huiyun Liu, Christian P. Pallasch, Rebecca Modiste, Quang‐Dé Nguyen, Jeffrey W. Craig, Elizabeth A. Morgan, Francisco Vega, Jon C. Aster, Kristopher A. Sarosiek, Alex K. Shalek, Michael T. Hemann, David M. Weinstock

    Published 2019
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  17. 17
    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma

    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma by Sharmistha Pal, Jakub Kaplan, Huy Nguyen, Sylwia A. Stopka, Milan R. Savani, Michael S. Regan, Quang‐Dé Nguyen, Kristen L. Jones, Lisa A. Moreau, Jingyu Peng, Marina DiPiazza, Andrew J. Perciaccante, Xiaoting Zhu, Bradley R. Hunsel, Kevin X. Liu, Sanda Alexandrescu, Rachid Drissi, Mariella G. Filbin, Samuel K. McBrayer, Nathalie Y.R. Agar, Dipanjan Chowdhury, Daphne A. Haas‐Kogan

    Published 2022
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  18. 18
    Combination inhibition of PI3K and mTORC1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases

    Combination inhibition of PI3K and mTORC1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases by Jing Ni, Shakti Ramkissoon, Shaozhen Xie, Shom Goel, Daniel G. Stover, Hanbing Guo, Victor Luu, Eugenio Marco, Lori Ramkissoon, Yun Jee Kang, Marika Hayashi, Quang‐Dé Nguyen, Azra H. Ligon, Rose Du, Elizabeth B. Claus, Brian M. Alexander, Guo‐Cheng Yuan, Zhigang C. Wang, J. Dirk Iglehart, Ian E. Krop, Thomas M. Roberts, Eric P. Winer, Nancy U. Lin, Keith L. Ligon, Jean J. Zhao

    Published 2016
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  19. 19
    Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma

    Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma by J. Bryan Iorgulescu, Prafulla C. Gokhale, Maria C. Speranza, Benjamin K. Eschle, Michael J. Poitras, Margaret K. Wilkens, Kara M. Soroko, Chhayheng Chhoeu, Aine Knott, Yan Gao, Mary Jane Lim-Fat, Gregory J. Baker, Dennis M. Bonal, Quang‐Dé Nguyen, Gareth R. L. Grant, Keith L. Ligon, Peter K. Sorger, E. Antonio Chiocca, Ana C. Anderson, Paul T. Kirschmeier, Arlene H. Sharpe, Gordon J. Freeman, David A. Reardon

    Published 2020
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  20. 20
    Cells Lacking the <i>RB1</i> Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival

    Cells Lacking the <i>RB1</i> Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival by Matthew G. Oser, Raquel Fonseca, Abhishek A. Chakraborty, Rachel Brough, Alexander Spektor, Rebecca B. Jennings, Abdallah Flaifel, Jesse Novak, Aditi Gulati, Elizabeth Buss, Scott T. Younger, Samuel K. McBrayer, Glenn S. Cowley, Dennis M. Bonal, Quang-Dé Nguyen, Laura Brullé-Soumaré, Paula Taylor, Stefano Cairo, Colm J. Ryan, Elizabeth J. Pease, Kim Maratea, Jon Travers, David E. Root, Sabina Signoretti, David Pellman, Susan Ashton, Christopher J. Lord, Simon T. Barry, William G. Kaelin

    Published 2018
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