Rezultaty - Qing‐Bai She
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4E-BP1 Is a Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways that Integrates Their Function in Tumors od Qing‐Bai She, Ensar Halilovic, Qing Ye, Zhen Wei, Senji Shirasawa, Takehiko Sasazuki, David B. Solit, Neal Rosen
Wydane 2010Artigo -
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Breast Tumor Cells with PI3K Mutation or HER2 Amplification Are Selectively Addicted to Akt Signaling od Qing‐Bai She, Sarat Chandarlapaty, Qing Ye, Jose Lobo, Kathleen Haskell, Karen Leander, Deborah Defeo-Jones, Hans E. Huber, Neal Rosen
Wydane 2008Artigo -
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N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signals od Xiuping Huang, Qing Ye, Min Chen, Aimin Li, Wenting Mi, Yuxin Fang, Yekaterina Y. Zaytseva, Kathleen L. O’Connor, Craig W. Vander Kooi, Side Liu, Qing‐Bai She
Wydane 2019Artigo -
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mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt od Kathryn O’Reilly, F. Rojo, Qing‐Bai She, David B. Solit, Gordon B. Mills, Debra L. Smith, Heidi A. Lane, Francesco Hofmann, Daniel J. Hicklin, Dale L. Ludwig, José Baselga, Neal Rosen
Wydane 2006Artigo -
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Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression od Yubin Guo, Qing Ye, Pan Deng, Yanan Cao, Daheng He, Zhaohe Zhou, Chi Wang, Yekaterina Y. Zaytseva, Charles E. Schwartz, Eun Young Lee, B. Mark Evers, Andrew J. Morris, Side Liu, Qing‐Bai She
Wydane 2020Artigo -
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Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity od Lao H. Saal, Peter A. Johansson, Karolina Holm, Sofia K. Gruvberger-Saal, Qing‐Bai She, Matthew Maurer, Susan Koujak, Adolfo A. Ferrando, Per Malmström, Lorenzo Memeo, Jorma Isola, Pär‐Ola Bendahl, Neal Rosen, Hanina Hibshoosh, Markus Ringnér, Åke Borg, Ramon Parsons
Wydane 2007Artigo -
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Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects od Qing Ye, Yinan Zhang, Yanan Cao, Xiachang Wang, Yubin Guo, Jing Chen, Jamie Horn, Larissa V. Ponomareva, Luksana Chaiswing, Khaled A. Shaaban, Qiou Wei, Bradley D. Anderson, Daret K. St. Clair, Haining Zhu, Markos Leggas, Jon S. Thorson, Qing‐Bai She
Wydane 2019Artigo -
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Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer od Qing‐Bai She, Sofia K. Gruvberger-Saal, Matthew Maurer, Yilun Chen, Mervi Jumppanen, Tao Su, Meaghan Dendy, Ying-Ka Ingar Lau, Lorenzo Memeo, Hugo M. Horlings, Marc J. van de Vijver, Jorma Isola, Hanina Hibshoosh, Neal Rosen, Ramon Parsons, Lao H. Saal
Wydane 2016Artigo -
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Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring V600EBRAF od Fangrong Xing, Yogindra Persaud, Christine A. Pratilas, Barry S. Taylor, Manickam Janakiraman, Qing‐Bai She, Humilidad F. Gallardo, C. Liu, Taha Merghoub, Blake Hefter, Igor Dolgalev, Agnès Viale, Adriana Heguy, Elisa de Stanchina, David Cobrinik, Gideon Bollag, Jedd D. Wolchok, A Houghton, David B. Solit
Wydane 2011Artigo
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Biology
Cancer research
Cell biology
Signal transduction
Genetics
Cancer
Gene
PI3K/AKT/mTOR pathway
Protein kinase B
Biochemistry
Chemistry
Kinase
PTEN
Medicine
Phosphorylation
Internal medicine
MAPK/ERK pathway
Messenger RNA
Mutant
Protein kinase A
Repressor
Transcription factor
AKT1
AKT2
Apoptosis
Breast cancer
Cell
Cell culture
Cell cycle
Endocrinology