检索结果 - Prysyazhna, Oleksandra

Redox regulation of cGMP-dependent protein kinase Iα in the cardiovascular system 由 Prysyazhna, Oleksandra, Eaton, Philip

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Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension 由 Prysyazhna, Oleksandra, Rudyk, Olena, Eaton, Philip

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High blood pressure and lost EDHF response in redox dead Cys42Ser PKGIα knock-in mouse 由 Prysyazhna, Oleksandra, Rudyk, Olena, Eaton, Philip

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Tadalafil protects from doxorubicin-induced heart failure by attenuating PKG Iα disulfide dimerisation 由 Prysyazhna, Oleksandra, Burgoyne, Joseph R, Eaton, Philip

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Evaluating a possible role for PKG1α redox state in chronic hypoxia-induced pulmonary hypertension 由 Rudyk, Olena, Prysyazhna, Oleksandra, Zhao, Lan, Eaton, Philip

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Nitroglycerin fails to lower blood pressure in redox-dead Cys42Ser PKG1α knock-in mouse 由 Rudyk, Olena, Prysyazhna, Oleksandra, Burgoyne, Joseph R, Eaton, Philip

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Proof of Principle for a Novel Class of Antihypertensives That Target the Oxidative Activation of PKG Iα (Protein Kinase G Iα) 由 Burgoyne, Joseph R., Prysyazhna, Oleksandra, Richards, Daniel A., Eaton, Philip

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Protein kinase G oxidation contribute to hypotension and organ injury during sepsis 由 Rudyk, Olena, Phinikaridou, Alkystis, Prysyazhna, Oleksandra, Burgoyne, Joseph R, Botnar, Rene, Eaton, Philip

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Phosphodiesterase 5 Inhibition Limits Doxorubicin-induced Heart Failure by Attenuating Protein Kinase G Iα Oxidation 由 Prysyazhna, Oleksandra, Burgoyne, Joseph Robert, Scotcher, Jenna, Grover, Steven, Kass, David, Eaton, Philip

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Protein kinase G oxidation is a major cause of injury during sepsis 由 Rudyk, Olena, Phinikaridou, Alkystis, Prysyazhna, Oleksandra, Burgoyne, Joseph R., Botnar, René M., Eaton, Philip

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PKG1α oxidation negatively regulates food seeking behaviour and reward 由 Duraffourd, Celine, Huckstepp, Robert T.R., Braren, Ingke, Fernandes, Cathy, Brock, Olivier, Delogu, Alessio, Prysyazhna, Oleksandra, Burgoyne, Joseph, Eaton, Philip

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Blood Pressure–Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of cGMP-Dependent Protein Kinase 由 Prysyazhna, Oleksandra, Wolhuter, Kathryn, Switzer, Christopher, Santos, Celio, Yang, Xiaoping, Lynham, Steven, Shah, Ajay M., Eaton, Philip, Burgoyne, Joseph R.

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Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase 由 Charles, Rebecca L., Rudyk, Olena, Prysyazhna, Oleksandra, Kamynina, Alisa, Yang, Jun, Morisseau, Christophe, Hammock, Bruce D., Freeman, Bruce A., Eaton, Philip

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Analysis of Mitochondrial Proteins in the Surviving Myocardium after Ischemia Identifies Mitochondrial Pyruvate Carrier Expression as Possible Mediator of Tissue Viability 由 Fernández-Caggiano, Mariana, Prysyazhna, Oleksandra, Barallobre-Barreiro, Javier, CalviñoSantos, Ramón, Aldama López, Guillermo, Generosa Crespo-Leiro, Maria, Eaton, Philip, Doménech, Nieves

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Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension 由 Rudyk, Olena, Rowan, Alice, Prysyazhna, Oleksandra, Krasemann, Susanne, Hartmann, Kristin, Zhang, Min, Shah, Ajay M., Ruppert, Clemens, Weiss, Astrid, Schermuly, Ralph T., Ida, Tomoaki, Akaike, Takaaki, Zhao, Lan, Eaton, Philip

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Mitochondrial pyruvate carrier abundance mediates pathological cardiac hypertrophy 由 Fernandez-Caggiano, Mariana, Kamynina, Alisa, Francois, Asvi A., Prysyazhna, Oleksandra, Eykyn, Thomas R., Krasemann, Susanne, Crespo-Leiro, Maria G., Vieites, Maria Garcia, Bianchi, Katiuscia, Morales, Valle, Domenech, Nieves, Eaton, Philip

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Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling 由 Feelisch, Martin, Akaike, Takaaki, Griffiths, Kayleigh, Ida, Tomoaki, Prysyazhna, Oleksandra, Goodwin, Joanna J, Gollop, Nicholas D, Fernandez, Bernadette O, Minnion, Magdalena, Cortese-Krott, Miriam M, Borgognone, Alessandra, Hayes, Rosie M, Eaton, Philip, Frenneaux, Michael P, Madhani, Melanie

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Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank–Starling response 由 Scotcher, Jenna, Prysyazhna, Oleksandra, Boguslavskyi, Andrii, Kistamas, Kornel, Hadgraft, Natasha, Martin, Eva D., Worthington, Jenny, Rudyk, Olena, Rodriguez Cutillas, Pedro, Cuello, Friederike, Shattock, Michael J., Marber, Michael S., Conte, Maria R., Greenstein, Adam, Greensmith, David J., Venetucci, Luigi, Timms, John F., Eaton, Philip

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Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure 由 Sag, Can Martin, Schnelle, Moritz, Zhang, Juqian, Murdoch, Colin E., Kossmann, Sabine, Protti, Andrea, Santos, Celio X.C., Sawyer, Greta, Zhang, Xiaohong, Mongue-Din, Heloise, Richards, Daniel A., Brewer, Alison C., Prysyazhna, Oleksandra, Maier, Lars S., Wenzel, Philip, Eaton, Philip J., Shah, Ajay M.

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Phospholemman Phosphorylation Regulates Vascular Tone, Blood Pressure, and Hypertension in Mice and Humans 由 Boguslavskyi, Andrii, Tokar, Sergiy, Prysyazhna, Oleksandra, Rudyk, Olena, Sanchez-Tatay, David, Lemmey, Hamish A.L., Dora, Kim A., Garland, Christopher J., Warren, Helen R., Doney, Alexander, Palmer, Colin N.A., Caulfield, Mark J., Vlachaki Walker, Julia, Howie, Jacqueline, Fuller, William, Shattock, Michael J.

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