Search Results - Priya Koppikar

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  1. 1
    Identification of human papillomaviruses in tumors of the oral cavity in an Indian community

    Identification of human papillomaviruses in tumors of the oral cavity in an Indian community by Priya Koppikar, Ethel-Michele deVilliers, Rita Mulherkar

    Published 2004
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  2. 2
    Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell–stimulated T cells yet preserves immunity to recall antigen

    Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell–stimulated T cells yet preserves immunity to recall antigen by Brian C. Betts, Omar Abdel‐Wahab, Shane A. Curran, Erin T. St. Angelo, Priya Koppikar, Glenn Heller, Ross L. Levine, James W. Young

    Published 2011
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  3. 3
    Constitutive Activation of Signal Transducer and Activator of Transcription 5 Contributes to Tumor Growth, Epithelial-Mesenchymal Transition, and Resistance to Epidermal Growth Factor Receptor Targeting

    Constitutive Activation of Signal Transducer and Activator of Transcription 5 Contributes to Tumor Growth, Epithelial-Mesenchymal Transition, and Resistance to Epidermal Growth Fac... by Priya Koppikar, Vivian Wai Yan Lui, David Man, Sichuan Xi, Raymond L. Chai, Elizabeth G Nelson, Allison B.J. Tobey, Jennifer R. Grandis

    Published 2008
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  4. 4
    Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma

    Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma by Priya Koppikar, Seung-Ho Choi, Ann Marie Egloff, Quan-Ying Cai, Shinsuke Suzuki, Maria L. Freilino, Hiroshi Nozawa, Sufi M. Thomas, William E. Gooding, Jill M. Siegfried, Jennifer R. Grandis

    Published 2008
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  5. 5
    Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms

    Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms by Neha Bhagwat, Priya Koppikar, Matthew D. Keller, Sachie Marubayashi, Kaitlyn Shank, Raajit K. Rampal, Jun Qi, Maria Kleppe, Hardik J. Patel, Smit Shah, Tony Taldone, James E. Bradner, Gabriela Chiosis, Ross L. Levine

    Published 2014
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  6. 6
    JAK2V617F-Mediated Phosphorylation of PRMT5 Downregulates Its Methyltransferase Activity and Promotes Myeloproliferation

    JAK2V617F-Mediated Phosphorylation of PRMT5 Downregulates Its Methyltransferase Activity and Promotes Myeloproliferation by Fan Liu, Xinyang Zhao, Fabiana Perna, Lan Wang, Priya Koppikar, Omar Abdel‐Wahab, Michael W. Harr, Ross L. Levine, Hao Xu, Ayalew Tefferi, A DeBlasio, Megan Hatlen, Sílvia Menéndez, Stephen D. Nimer

    Published 2011
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  7. 7
    Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis

    Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis by Maria Kleppe, Matthew H. Spitzer, Sheng Li, Corinne E. Hill, Lauren Dong, Efthymia Papalexi, Sofie De Groote, Robert L. Bowman, Matthew D. Keller, Priya Koppikar, Franck Rapaport, Julie Teruya‐Feldstein, Jorge Gandara, Christopher E. Mason, Garry P. Nolan, Ross L. Levine

    Published 2017
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  8. 8
    AKT is a therapeutic target in myeloproliferative neoplasms

    AKT is a therapeutic target in myeloproliferative neoplasms by Irum Khan, Zan Huang, Qing Wen, Monika J. Stankiewicz, L. Gilles, Benjamin Goldenson, Roger A. Schultz, Lauren Diebold, Sandeep Gurbuxani, Christy Finke, Terra L. Lasho, Priya Koppikar, Animesh Pardanani, Brady L. Stein, Jessica K. Altman, Ross L. Levine, Ayalew Tefferi, John D. Crispino

    Published 2013
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  9. 9
    HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans

    HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans by Sachie Marubayashi, Priya Koppikar, Tony Taldone, Omar Abdel‐Wahab, Nathan West, Neha Bhagwat, Eloisi Caldas-Lopes, Kenneth N. Ross, Mithat Gönen, Alex Gozman, James H. Ahn, Anna Rodina, Ouathek Ouerfelli, Guangbin Yang, Cyrus V. Hedvat, James E. Bradner, Gabriela Chiosis, Ross L. Levine

    Published 2010
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  10. 10
    Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition

    Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition by Qiang Wen, Qiong Yang, Benjamin Goldenson, Sébastien Malinge, Terra L. Lasho, Rebekka K. Schneider, Lawrence J. Breyfogle, Rachael Schultz, Laure Gilles, Priya Koppikar, Omar Abdel‐Wahab, Animesh Pardanani, Brady L. Stein, Sandeep Gurbuxani, Ann Mullally, Ross L. Levine, Ayalew Tefferi, John D. Crispino

    Published 2015
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  11. 11
    Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis

    Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis by Priya Koppikar, Omar Abdel‐Wahab, Cyrus V. Hedvat, Sachie Marubayashi, Jay Patel, Aviva Goel, Nicole Kucine, Jeffrey R. Gardner, Andrew P. Combs, Kris Vaddi, Patrick J. Haley, Timothy C. Burn, Mark Rupar, Jacqueline Bromberg, Mark Heaney, Elisa de Stanchina, Jordan S. Fridman, Ross L. Levine

    Published 2010
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  12. 12
    Heterodimeric JAK–STAT activation as a mechanism of persistence to JAK2 inhibitor therapy

    Heterodimeric JAK–STAT activation as a mechanism of persistence to JAK2 inhibitor therapy by Priya Koppikar, Neha Bhagwat, Outi Kilpivaara, Taghi Manshouri, Mazhar Adli, Todd Hricik, Fan Liu, Lindsay Saunders, Ann Mullally, Omar Abdel‐Wahab, Laura Leung, Abby Weinstein, Sachie Marubayashi, Aviva Goel, Mithat Gönen, Zeev Estrov, Benjamin L. Ebert, Gabriela Chiosis, Stephen D. Nimer, B Bernstein, Srđan Verstovšek, Ross L. Levine

    Published 2012
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  13. 13
    JAK–STAT Pathway Activation in Malignant and Nonmalignant Cells Contributes to MPN Pathogenesis and Therapeutic Response

    JAK–STAT Pathway Activation in Malignant and Nonmalignant Cells Contributes to MPN Pathogenesis and Therapeutic Response by Maria Kleppe, Minsuk Kwak, Priya Koppikar, Markus Riester, Matthew D. Keller, Lennart Bastian, Todd Hricik, Neha Bhagwat, Anna Sophia McKenney, Efthymia Papalexi, Omar Abdel‐Wahab, Raajit K. Rampal, Sachie Marubayashi, Jonathan J. Chen, Vincent Romanet, Jordan S. Fridman, Jacqueline Bromberg, Julie Teruya‐Feldstein, Masato Murakami, Thomas Radimerski, Franziska Michor, Rong Fan, Ross L. Levine

    Published 2015
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  14. 14
    Intratumoral Epidermal Growth Factor Receptor Antisense DNA Therapy in Head and Neck Cancer: First Human Application and Potential Antitumor Mechanisms

    Intratumoral Epidermal Growth Factor Receptor Antisense DNA Therapy in Head and Neck Cancer: First Human Application and Potential Antitumor Mechanisms by Stephen Y. Lai, Priya Koppikar, Sufi M. Thomas, Erin E. Childs, Ann Marie Egloff, Raja R. Seethala, Barton F. Branstetter, William E. Gooding, Ashok Muthukrishnan, James M. Mountz, Vivian Wai Yan Lui, Dong M. Shin, Sanjiv S. Agarwala, Rita Johnson, Larry A. Couture, Eugene N. Myers, Jonas T. Johnson, Gordon B. Mills, Athanassios Argiris, Jennifer R. Grandis

    Published 2009
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  15. 15
    Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent

    Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent by Rita Andraos, Zhiyan Qian, Débora Bonenfant, Joëlle Rubert, Eric Vangrevelinghe, Clemens Scheufler, Fanny Marque, Catherine H. Régnier, Alain De Pover, Hugues Ryckelynck, Neha Bhagwat, Priya Koppikar, Aviva Goel, Lorenza Wyder, Gisele Tavares, Fabienne Baffert, Carole Pissot‐Soldermann, Paul W. Manley, Christoph Gaul, Hans Voshol, Ross L. Levine, William R. Sellers, Francesco Hofmann, Thomas Radimerski

    Published 2012
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  16. 16
    Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias

    Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias by Nicole Kucine, Sachie Marubayashi, Neha Bhagwat, Efthymia Papalexi, Priya Koppikar, Marta Sanchez Martin, Lauren Dong, Marty S. Tallman, Elisabeth Paietta, Kai Wang, Jie He, Doron Lipson, Phil Stephens, V. A. Miller, Jacob M. Rowe, Julie Teruya‐Feldstein, Charles G. Mullighan, Adolfo A. Ferrando, Andrei V. Krivtsov, Scott A. Armstrong, Laura Leung, Stefan O. Ochiana, Gabriela Chiosis, Ross L. Levine, Maria Kleppe

    Published 2015
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  17. 17
    Characterization of a Novel FLT3 BiTE Molecule for the Treatment of Acute Myeloid Leukemia

    Characterization of a Novel FLT3 BiTE Molecule for the Treatment of Acute Myeloid Leukemia by Bettina Brauchle, Rebecca Goldstein, Christine M. Karbowski, Anja Henn, Chi-Ming Li, Veit Bücklein, Christina Krupka, Michael C. Boyle, Priya Koppikar, Sascha Haubner, Joachim Wahl, Christoph Dahlhoff, Tobias Raum, Matthew J. Rardin, Christine Sastri, Dan A. Rock, Michael von Bergwelt‐Baildon, Brendon Frank, Klaus H. Metzeler, Ryan Case, Matthias Friedrich, Mercedesz Balázs, Karsten Spiekermann, Angela Coxon, Marion Subklewe, Tara Arvedson

    Published 2020
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  18. 18
    CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms

    CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms by Sara C. Meyer, Matthew D. Keller, Sophia Chiu, Priya Koppikar, Olga A. Guryanova, Franck Rapaport, Ke Xu, Katia Manova, Dmitry Pankov, Richard J. O’Reilly, Maria Kleppe, Anna Sophia McKenney, Alan H. Shih, Kaitlyn Shank, Jihae Ahn, Eftymia Papalexi, Barbara Spitzer, Nick Socci, Agnès Viale, Emeline Mandon, Nicolas Ebel, Rita Andraos, Joëlle Rubert, Ernesta Dammassa, Vincent Romanet, Arno Dölemeyer, Michael Zender, Melanie Heinlein, Raajit K. Rampal, Rona Singer Weinberg, Ronald Hoffman, William R. Sellers, Francesco Hofmann, Masato Murakami, Fabienne Baffert, Christoph Gaul, Thomas Radimerski, Ross L. Levine

    Published 2015
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  19. 19
    Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias

    Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias by Won Jun Kim, Edie I. Crosse, Emma De Neef, Iñaki Etxeberría, Erich Sabio, Eric Wang, Jan Philipp Bewersdorf, Kuan‐Ting Lin, Sydney X. Lu, Andrea E. Belleville, Nina Fox, Cynthia Castro, Pu Zhang, Takeshi Fujino, Jennifer Lewis, Jahan Rahman, Beatrice Zhang, Jeffrey D. Winick, Alexander M. Lewis, Robert F. Stanley, Susan DeWolf, Brigita Meškauskaitė Urben, Meril Takizawa, Tobias Krause, Henrik Molina, Ronan Chaligné, Priya Koppikar, Jeffrey J. Molldrem, Mathieu Gigoux, Taha Merghoub, Anthony F. Daniyan, Smita S. Chandran, Benjamin D. Greenbaum, Christopher A. Klebanoff, Robert K. Bradley, Omar Abdel‐Wahab

    Published 2025
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