Resultados da pesquisa - Phoenix, Timothy N

Spred1, a negative regulator of Ras–MAPK–ERK, is enriched in CNS germinal zones, dampens NSC proliferation, and maintains ventricular zone structure Por Phoenix, Timothy N., Temple, Sally

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HGG-13. DETERMINING REGIONAL DIFFERENCES IN HIGH-GRADE GLIOMA VASCULATURE PHENOTYPE Por Wei, Xin, Hartley, Rachel, Bear, Heather, Fuller, Christine, Phoenix, Timothy N

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Defining tumor-associated vascular heterogeneity in pediatric high-grade and diffuse midline gliomas Por Wei, Xin, Meel, Michaël H., Breur, Marjolein, Bugiani, Marianna, Hulleman, Esther, Phoenix, Timothy N.

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Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain Por Fasano, Christopher A., Phoenix, Timothy N., Kokovay, Erzsebet, Lowry, Natalia, Elkabetz, Yechiel, Dimos, John T., Lemischka, Ihor R., Studer, Lorenz, Temple, Sally

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Generation of diffuse intrinsic pontine glioma mouse models by brainstem-targeted in utero electroporation Por Patel, Smruti K, Hartley, Rachel M, Wei, Xin, Furnish, Robin, Escobar-Riquelme, Fernanda, Bear, Heather, Choi, Kwangmin, Fuller, Christine, Phoenix, Timothy N

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DIPG-22. DISSECTING THE ONCOGENIC ROLE OF FOXR2 IN DIFFUSE INTRINSIC PONTINE GLIOMA Por Tsai, Jessica W, Patel, Smruti K, Bear, Heather, Dubois, Frank, Khadka, Prasidda, Lu, Sophie, Gonzalez, Elizabeth, Ligon, Keith, Bandopadhayay, Pratiti, Phoenix, Timothy N

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Molecular Characterisation of Transport Mechanisms at the Developing Mouse Blood–CSF Interface: A Transcriptome Approach Por Liddelow, Shane A., Temple, Sally, Møllgård, Kjeld, Gehwolf, Renate, Wagner, Andrea, Bauer, Hannelore, Bauer, Hans-Christian, Phoenix, Timothy N., Dziegielewska, Katarzyna M., Saunders, Norman R.

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Correction: Molecular Characterisation of Transport Mechanisms at the Developing Mouse Blood–CSF Interface: A Transcriptome Approach Por Liddelow, Shane A., Temple, Sally, Møllgård, Kjeld, Gehwolf, Renate, Wagner, Andrea, Bauer, Hannelore, Bauer, Hans-Christian, Phoenix, Timothy N., Dziegielewska, Katarzyna M., Saunders, Norman R.

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Glioblastoma genetic drivers dictate the function of tumor-associated macrophages/microglia and responses to CSF1R inhibition Por Rao, Rohit, Han, Rong, Ogurek, Sean, Xue, Chengbin, Wu, Lai Man, Zhang, Liguo, Zhang, Li, Hu, Jian, Phoenix, Timothy N, Waggoner, Stephen N, Lu, Q Richard

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Medulloblastoma genotype dictates blood brain barrier phenotype Por Phoenix, Timothy N., Patmore, Deanna M., Boop, Scott, Boulos, Nidal, Jacus, Megan O., Patel, Yogesh T., Roussel, Martine F, Finkelstein, David, Goumnerova, Lilian, Perreault, Sebastien, Wadhwa, Elizabeth, Cho, Yoon-Jae, Stewart, Clinton F., Gilbertson, Richard J.

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Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma Por du Chatinier, Aimée, Meel, Michaël H, Das, Arvid I, Metselaar, Dennis S, Waranecki, Piotr, Bugiani, Marianna, Breur, Marjolein, Simonds, Erin F, Lu, Edbert D, Weiss, William A, Garcia Vallejo, Juan J, Hoving, Eelco W, Phoenix, Timothy N, Hulleman, Esther

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MEK/MELK inhibition and blood–brain barrier deficiencies in atypical teratoid/rhabdoid tumors Por Meel, Michaël H, Guillén Navarro, Miriam, de Gooijer, Mark C, Metselaar, Dennis S, Waranecki, Piotr, Breur, Marjolein, Lagerweij, Tonny, Wedekind, Laurine E, Koster, Jan, van de Wetering, Marianne D, Schouten-van Meeteren, Netteke, Aronica, Eleonora, van Tellingen, Olaf, Bugiani, Marianna, Phoenix, Timothy N, Kaspers, Gertjan J L, Hulleman, Esther

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Epigenetically defined therapeutic targeting in H3G34R/V high-grade gliomas Por Sweha, Stefan R., Chung, Chan, Natarajan, Siva Kumar, Panwalkar, Pooja, Pun, Matthew, Ghali, Amer, Bayliss, Jill, Pratt, Drew, Shankar, Anand, Ravikumar, Visweswaran, Rao, Arvind, Cieslik, Marcin, Wilder-Romans, Kari, Scott, Andrew J., Wahl, Daniel R., Jessa, Selin, Kleinman, Claudia L., Jabado, Nada, Mackay, Alan, Jones, Chris, Martinez, Daniel, Santi, Mariarita, Judkins, Alexander R., Yadav, Viveka Nand, Qin, Tingting, Phoenix, Timothy N., Koschmann, Carl J., Baker, Suzanne J., Chinnaiyan, Arul M., Venneti, Sriram

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Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma Por Miklja, Zachary, Yadav, Viveka Nand, Cartaxo, Rodrigo T., Siada, Ruby, Thomas, Chase C., Cummings, Jessica R., Mullan, Brendan, Stallard, Stefanie, Paul, Alyssa, Bruzek, Amy K., Wierzbicki, Kyle, Yang, Tao, Garcia, Taylor, Wolfe, Ian, Leonard, Marcia, Robertson, Patricia L., Garton, Hugh J.L., Wahl, Daniel R., Parmar, Hemant, Sarkaria, Jann N., Kline, Cassie, Mueller, Sabine, Nicolaides, Theodore, Glasser, Chana, Leary, Sarah E.S., Venneti, Sriram, Kumar-Sinha, Chandan, Chinnaiyan, Arul M., Mody, Rajen, Pai, Manjunath P., Phoenix, Timothy N., Marini, Bernard L., Koschmann, Carl

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C11orf95-RELA fusions drive oncogenic NF-κB signaling in ependymoma Por Parker, Matthew, Mohankumar, Kumarasamypet M., Punchihewa, Chandanamali, Weinlich, Ricardo, Dalton, James D., Li, Yongjin, Lee, Ryan, Tatevossian, Ruth G., Phoenix, Timothy N., Thiruvenkatam, Radhika, White, Elsie, Tang, Bo, Orisme, Wilda, Gupta, Kirti, Rusch, Michael, Chen, Xiang, Li, Yuxin, Nagahawhatte, Panduka, Hedlund, Erin, Finkelstein, David, Wu, Gang, Shurtleff, Sheila, Easton, John, Boggs, Kristy, Yergeau, Donald, Vadodaria, Bhavin, Mulder, Heather L, Becksford, Jared, Gupta, Pankaj, Huether, Robert, Ma, Jing, Song, Guangchun, Gajjar, Amar, Merchant, Thomas, Boop, Frederick, Smith, Amy A, Ding, Li, Lu, Charles, Ochoa, Kerri, Zhao, David, Fulton, Robert S, Fulton, Lucinda L, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Green, Douglas R., Zhang, Jinghui, Ellison, David W., Gilbertson, Richard J.

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Novel mutations target distinct subgroups of medulloblastoma Por Robinson, Giles, Parker, Matthew, Kranenburg, Tanya A., Lu, Charles, Chen, Xiang, Ding, Li, Phoenix, Timothy N., Hedlund, Erin, Wei, Lei, Zhu, Xiaoyan, Chalhoub, Nader, Baker, Suzanne J., Huether, Robert, Kriwacki, Richard, Curley, Natasha, Thiruvenkatam, Radhika, Wang, Jianmin, Wu, Gang, Rusch, Michael, Hong, Xin, Beckford, Jared, Gupta, Pankaj, Ma, Jing, Easton, John, Vadodaria, Bhavin, Onar-Thomas, Arzu, Lin, Tong, Li, Shaoyi, Pounds, Stanley, Paugh, Steven, Zhao, David, Kawauchi, Daisuke, Roussel, Martine F., Finkelstein, David, Ellison, David W., Lau, Ching C., Bouffet, Eric, Hassall, Tim, Gururangan, Sridharan, Cohn, Richard, Fulton, Robert S., Fulton, Lucinda L., Dooling, David J., Ochoa, Kerri, Gajjar, Amar, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Zhang, Jinghui, Gilbertson, Richard J.

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C11ORF95-RELA FUSIONS DRIVE ONCOGENIC NF-KB SIGNALING IN EPENDYMOMA Por Gilbertson, Richard, Parker, Matthew, Mohankumar, Kumarasamypet M., Punchihewa, Chandanamali, Weinlich, Ricardo, Dalton, James D., Li, Yongjin, Lee, Ryan, Tatevossian, Ruth G., Phoenix, Timothy N., Thiruvenkatam, Radhika, White, Elsie, Tang, Bo, Orisme, Wilda, Gupta, Kirti, Rusch, Michael, Chen, Xiang, Li, Yuxin, Nagahawhatta, Panduka, Hedlund, Erin, Finkelstein, David, Wu, Gang, Shurtleff, Sheila, Easton, John, Boggs, Kristy, Yergeau, Donald, Vadodaria, Bhavin, Mulder, Heather L., Becksford, Jared, Gupta, Pankaj, Huether, Robert, Ma, Jing, Song, Guangchun, Gajjar, Amar, Merchant, Thomas, Boop, Frederick, Smith, Amy A, Ding, Li, Lu, Charles, Ochoa, Kerri, Zhao, David, Fulton, Robert S., Fulton, Lucinda L., Mardis, Elaine R., Wilson, Richard K., Downing, James R., Green, Douglas R., Zhang, Jinghui, Ellison, David W., Gilbertson, Richard J.

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DIPG-19. FOXR2 is an oncogenic driver across pediatric and adult cancers Por Tsai, Jessica W, Cejas, Paloma, Wang, Dayle K, Patel, Smruti, Wu, David W, Arounleut, Phonepasong, Wei, Xin, Zhou, Ningxuan, Syamala, Sudeepa, Dubois, Frank P B, Crane, Alexander, Pelton, Kristine, Vogelzang, Jayne, Sousa, Cecilia, Baguette, Audrey, Chen, Xiaolong, Condurat, Alexandra L, Dixon-Clarke, Sarah E, Zhou, Kevin N, Lu, Sophie D, Gonzalez, Elizabeth M, Chacon, Madison S, Digiacomo, Jeromy J, Kumbhani, Rushil, Novikov, Dana, Hunter, J'Ya, Tsoli, Maria, Ziegler, David S, Dirksen, Uta, Jager, Natalie, Balasubramanian, Gnana Prakash, Kramm, Christof M, Nathrath, Michaela, Bielack, Stefan, Baker, Suzanne J, Zhang, Jinghui, McFarland, James M, Getz, Gad, Aguet, Francois, Jabado, Nada, Witt, Olaf, Pfister, Stefan M, Ligon, Keith L, Kleinman, Claudia L, Long, Henry, Jones, David T W, Bandopadhayay, Pratiti, Phoenix, Timothy N

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Resolving medulloblastoma cellular architecture by single-cell genomics Por Hovestadt, Volker, Smith, Kyle S., Bihannic, Laure, Filbin, Mariella G., Shaw, McKenzie L., Baumgartner, Alicia, DeWitt, John C., Groves, Andrew, Mayr, Lisa, Weisman, Hannah R., Richman, Alyssa R., Shore, Marni E., Goumnerova, Liliana, Rosencrance, Celeste, Carter, Robert A., Phoenix, Timothy N., Hadley, Jennifer L., Tong, Yiai, Houston, Jim, Ashmun, Richard A., DeCuypere, Michael, Sharma, Tanvi, Flasch, Diane, Silkov, Antonina, Ligon, Keith, Pomeroy, Scott L., Rivera, Miguel N., Rozenblatt-Rosen, Orit, Rusert, Jessica M., Wechsler-Reya, Robert J., Li, Xiao-Nan, Peyrl, Andreas, Gojo, Johannes, Kirchhofer, Dominik, Lötsch, Daniela, Czech, Thomas, Dorfer, Christian, Haberler, Christine, Geyeregger, Rene, Halfmann, Angela, Gawad, Charles, Easton, John, Pfister, Stefan M., Regev, Aviv, Gajjar, Amar, Orr, Brent A., Slavc, Irene, Robinson, Giles W., Bernstein, Bradley E., Suvà, Mario L., Northcott, Paul A.

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PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation Por Khadka, Prasidda, Reitman, Zachary J., Lu, Sophie, Buchan, Graham, Gionet, Gabrielle, Dubois, Frank, Carvalho, Diana M., Shih, Juliann, Zhang, Shu, Greenwald, Noah F., Zack, Travis, Shapira, Ofer, Pelton, Kristine, Hartley, Rachel, Bear, Heather, Georgis, Yohanna, Jarmale, Spandana, Melanson, Randy, Bonanno, Kevin, Schoolcraft, Kathleen, Miller, Peter G., Condurat, Alexandra L., Gonzalez, Elizabeth M., Qian, Kenin, Morin, Eric, Langhnoja, Jaldeep, Lupien, Leslie E., Rendo, Veronica, Digiacomo, Jeromy, Wang, Dayle, Zhou, Kevin, Kumbhani, Rushil, Guerra Garcia, Maria E., Sinai, Claire E., Becker, Sarah, Schneider, Rachel, Vogelzang, Jayne, Krug, Karsten, Goodale, Amy, Abid, Tanaz, Kalani, Zohra, Piccioni, Federica, Beroukhim, Rameen, Persky, Nicole S., Root, David E., Carcaboso, Angel M., Ebert, Benjamin L., Fuller, Christine, Babur, Ozgun, Kieran, Mark W., Jones, Chris, Keshishian, Hasmik, Ligon, Keith L., Carr, Steven A., Phoenix, Timothy N., Bandopadhayay, Pratiti

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