Search Results - Phillippa Dudley
- Showing 1 - 3 results of 3
-
1
Intermittent High-Dose Scheduling of AZD8835, a Novel Selective Inhibitor of PI3Kα and PI3Kδ, Demonstrates Treatment Strategies for <i>PIK3CA</i>-Dependent Breast Cancers by Kevin Hudson, Urs J. Hancox, Cath Trigwell, Robert McEwen, Urszula M. Polanska, Myria Nikolaou, Pablo Morentin Gutierrez, Alvaro Avivar‐Valderas, Oona Delpuech, Phillippa Dudley, Lyndsey Hanson, Rebecca Ellston, Alys Jones, Marie Cumberbatch, Sabina Cosulich, Lara Ward, Francisco Cruzalegui, Stephen Green
Published 2016Artigo -
2
Preclinical Pharmacology of AZD5363, an Inhibitor of AKT: Pharmacodynamics, Antitumor Activity, and Correlation of Monotherapy Activity with Genetic Background by Barry R. Davies, Hannah E. Greenwood, Phillippa Dudley, Claire Crafter, Dehua Yu, Jingchuan Zhang, Jing Li, Beirong Gao, Qunsheng Ji, Juliana Maynard, Sally‐Ann Ricketts, Darren A.E. Cross, Sabina Cosulich, Christine C. Chresta, Ken Page, James Yates, Clare Lane, Rebecca Watson, Richard Luke, Donald Ogilvie, Martin Pass
Published 2012Artigo -
3
AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with <i>In vitro</i> and <i>In vivo</i> Antitumor Activity by Christine M. Chresta, Barry R. Davies, Ian Hickson, Tom Harding, Sabina Cosulich, Susan E. Critchlow, John P. Vincent, Rebecca Ellston, Darren Jones, Patrizia Sini, Dominic I. James, Zoë Howard, Phillippa Dudley, Gareth Hughes, Lisa M. Smith, Sharon Maguire, Marc Hummersone, Karine Malagu, Keith Menear, Richard O. Jenkins, Matt Jacobsen, Graeme C.M. Smith, Sylvie M. Guichard, Martin Pass
Published 2009Artigo
Search Tools:
Related Subjects
Biochemistry
Pharmacology
Biology
Breast cancer
Cancer
Cancer research
Chemistry
Internal medicine
Medicine
PI3K/AKT/mTOR pathway
Phosphorylation
Protein kinase B
Apoptosis
Biotechnology
Cell growth
Docetaxel
Drug
Estrogen receptor
In vitro
In vivo
Kinase
Mechanistic target of rapamycin
Pharmacodynamics
Pharmacokinetics
Potency
Signal transduction
Therapeutic index
Trastuzumab
Triple-negative breast cancer
mTORC1