检索结果 - Philip B. Verghese
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A randomized controlled study to evaluate the effect of bexarotene on amyloid‐β and apolipoprotein E metabolism in healthy subjects 由 Kaushik Ghosal, Michael Haag, Philip B. Verghese, Tim West, T VEENSTRA, Joel B. Braunstein, Randall J. Bateman, David M. Holtzman, Gary E. Landreth
出版 2016Artigo -
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Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism 由 Qingyi Ma, Zhen Zhao, Abhay P. Sagare, Yingxi Wu, Min Wang, Nelly Chuqui Owens, Philip B. Verghese, Joachim Herz, David M. Holtzman, Berislav V. Zloković
出版 2018Artigo -
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Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death 由 Philip B. Verghese, Yo Sasaki, Donghan M. Yang, Floy R. Stewart, Fatima Sabar, Mary Beth Finn, Christine M. Wroge, Steven Mennerick, Jeffrey J. Neil, Jeffrey Milbrandt, David M. Holtzman
出版 2011Artigo -
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Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation 由 Thiyagaragan M. Achariyar, Baoman Li, Weiguo Peng, Philip B. Verghese, Yang Shi, Evan McConnell, Abdellatif Benraiss, Tristan Kasper, Wei Song, Takahiro Takano, David M. Holtzman, Maiken Nedergaard, Rashid Deane
出版 2016Artigo -
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Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis 由 Joseph M. Castellano, Rashid Deane, Andrew J. Gottesdiener, Philip B. Verghese, Floy R. Stewart, Tim West, Andrew C. Paoletti, Tristan Kasper, Ronald B. DeMattos, Berislav V. Zloković, David M. Holtzman
出版 2012Artigo -
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In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis 由 Jason D. Ulrich, Jack M. Burchett, Jessica L. Restivo, Dorothy R. Schuler, Philip B. Verghese, Thomas E. Mahan, Gary E. Landreth, Joseph M. Castellano, Hong Jiang, John R. Cirrito, David M. Holtzman
出版 2013Artigo -
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Targeting Apolipoprotein E/Amyloid β Binding by Peptoid CPO_Aβ17-21 P Ameliorates Alzheimer’s Disease Related Pathology and Cognitive Decline 由 Shan Liu, Shin-Ae Park, Garrett Allington, Frances Prelli, Yanjie Sun, Mitchell Martá-Ariza, Henrieta Scholtzova, Goutam Biswas, Bernard J. Treves Brown, Philip B. Verghese, Pankaj Mehta, Yong-Uk Kwon, Thomas Wısnıewskı
出版 2017Artigo -
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The PrecivityAD™ test: Accurate and reliable LC-MS/MS assays for quantifying plasma amyloid beta 40 and 42 and apolipoprotein E proteotype for the assessment of brain amyloidosis 由 Kristopher M. Kirmess, Matthew R. Meyer, Mary S. Holubasch, S Knapik, Yan Hu, Erin N. Jackson, Scott E. Harpstrite, Philip B. Verghese, Tim West, I. Fogelman, Joel B. Braunstein, Kevin E. Yarasheski, John H. Contois
出版 2021Artigo -
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Clinical Utility of an Alzheimer’s Disease Blood Test Among Cognitively Impaired Patients: Results from the Quality Improvement PrecivityAD2 (QUIP II) Clinician Survey Study 由 Mark Monane, Demetrius M. Maraganore, Robert G. Carlile, Kim Johnson, David A. Merrill, Darren R. Gitelman, Kenneth S. Sharlin, Lawren VandeVrede, Kristi K. George, Jimin Wang, Tim West, Leslie Jacobs, Philip B. Verghese, Joel B. Braunstein
出版 2025Artigo -
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A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysi... 由 Tim West, Kristopher M. Kirmess, Matthew R. Meyer, Mary S. Holubasch, S Knapik, Yan Hu, John H. Contois, Erin N. Jackson, Scott E. Harpstrite, Randall J. Bateman, David M. Holtzman, Philip B. Verghese, I. Fogelman, Joel B. Braunstein, Kevin E. Yarasheski
出版 2021Artigo -
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microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain 由 Jaekwang Kim, Hyejin Yoon, Takahiro Horie, Jack M. Burchett, Jessica L. Restivo, Noemí Rotllán, Cristina M. Ramírez, Philip B. Verghese, Masafumi Ihara, Hyang-Sook Hoe, Christine Esau, Carlos Fernández‐Hernando, David M. Holtzman, John R. Cirrito, Koh Ono, Jungsu Kim
出版 2015Artigo -
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Comparison of plasma and <scp>CSF</scp> biomarkers in predicting cognitive decline 由 Andrew J. Aschenbrenner, Yan Li, Rachel L. Henson, Katherine Volluz, Jason Hassenstab, Philip B. Verghese, Tim West, Matthew R. Meyer, Kristopher M. Kirmess, Anne M. Fagan, Chengjie Xiong, David M. Holtzman, John C. Morris, Randall J. Bateman, Suzanne E. Schindler
出版 2022Artigo
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