نتائج البحث - Petr Pávek

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  1. 1
    Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions

    Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions حسب Petr Pávek

    منشور في 2016
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  2. 2
    Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily

    Post-translational and Post-transcriptional Modifications of Pregnane X Receptor (PXR) in Regulation of the Cytochrome P450 Superfamily حسب Tomáš Smutný, Sridhar Mani, Petr Pávek

    منشور في 2013
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  3. 3
    Pregnane X Receptor and Cancer: Context-Specificity is Key

    Pregnane X Receptor and Cancer: Context-Specificity is Key حسب Satyanarayana R. Pondugula, Petr Pávek, Sridhar Mani

    منشور في 2016
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    Artigo
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  4. 4
    Rifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human Hepatocytes

    Rifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human Hepatocytes حسب Petr Pávek, Lucie Stejskalová, Lucie Krausová, Michal Bitman, Radim Vrzal, Zdeněk Dvořák

    منشور في 2012
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  5. 5
    Metformin induces <scp>PGC</scp>‐1α expression and selectively affects hepatic <scp>PGC</scp>‐1α functions

    Metformin induces <scp>PGC</scp>‐1α expression and selectively affects hepatic <scp>PGC</scp>‐1α functions حسب Sanna‐Mari Aatsinki, Marcin Buler, Henriikka Salomäki, Markku Koulu, Petr Pávek, Jukka Hakkola

    منشور في 2014
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    Artigo
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  6. 6
    Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene

    Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene حسب Lucie Krausová, Lucie Stejskalová, Hongwei Wang, Radim Vrzal, Zdeněk Dvořák, Sridhar Mani, Petr Pávek

    منشور في 2011
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  7. 7
    Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug‐metabolizing cytochrome P450 enzymes

    Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug‐metabolizing cytochrome P450 enzymes حسب Alice Rulcová, Ilona Prokopová, Lucie Krausová, Michal Bitman, Radim Vrzal, Zdeněk Dvořák, J Blahoš, Petr Pávek

    منشور في 2010
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    Artigo
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  8. 8
    Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 gene

    Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 gene حسب Petr Pávek, Kateřina Pospěchová, Lucie Svecova, Zdeňka Syrová, Lucie Stejskalová, Jana Blažková, Zdeněk Dvořák, Jaroslav Blahoš

    منشور في 2009
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  9. 9
    When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists

    When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists حسب Alejandro Díaz‐Holguín, Azam Rashidian, Dirk Pijnenburg, Gláucio Monteiro Ferreira, Alžbeta Štefela, Miroslav Kašpar, Eva Kudová, Antti Poso, Rinie van Beuningen, Petr Pávek, Thales Kronenberger

    منشور في 2022
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  10. 10
    Front Cover: When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists (ChemMedChem 4/2023)

    Front Cover: When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists (ChemMedChem 4/2023) حسب Alejandro Díaz‐Holguín, Azam Rashidian, Dirk Pijnenburg, Gláucio Monteiro Ferreira, Alžbeta Štefela, Miroslav Kašpar, Eva Kudová, Antti Poso, Rinie van Beuningen, Petr Pávek, Thales Kronenberger

    منشور في 2023
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    Paratexto
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  11. 11
    Targeted Protein Degradation (TPD) for Immunotherapy: Understanding Proteolysis Targeting Chimera-Driven Ubiquitin-Proteasome Interactions

    Targeted Protein Degradation (TPD) for Immunotherapy: Understanding Proteolysis Targeting Chimera-Driven Ubiquitin-Proteasome Interactions حسب Rajamanikkam Kamaraj, Subhrojyoti Ghosh, Souvadra Das, Shinjini Sen, Priyanka Kumar, Madhurima Majumdar, R. Dasgupta, Sampurna Mukherjee, Shrimanti Das, Indrilla Ghose, Petr Pávek, Muruga Poopathi Raja Karuppiah, Anil A. Chuturgoon, Krishnan Anand

    منشور في 2024
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  12. 12
    Unexpected Effects of Propiconazole, Tebuconazole, and Their Mixture on the Receptors CAR and PXR in Human Liver Cells

    Unexpected Effects of Propiconazole, Tebuconazole, and Their Mixture on the Receptors CAR and PXR in Human Liver Cells حسب Constanze Knebel, Jannika Neeb, Elisabeth Zahn, Flávia de Holanda Schmidt, Alejandro Carazo, Ondřej Holas, Petr Pávek, Gerhard P. Püschel, Ulrich M. Zanger, Roderich D. Süßmuth, Alfonso Lampen, Philip Marx‐Stoelting, Albert Braeuning

    منشور في 2018
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  13. 13
    The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model

    The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model حسب Ján Dušek, Ivana Mejdrová, Klára Dohnalová, Tomáš Smutný, Karel Chalupský, Mária Krutáková, Josef Škoda, Azam Rashidian, Ivona Pávková, Kryštof Škach, Jana Hricová, Michaela Chocholoušková, Lucie Smutná, Rajamanikkam Kamaraj, M Hroch, Martin Leníček, Stanislav Mičuda, Dirk Pijnenburg, Rinie van Beuningen, Michal Holčapek, Libor Vı́tek, Magnus Ingelman‐Sundberg, Oliver Burk, Thales Kronenberger, Radim Nencka, Petr Pávek

    منشور في 2025
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  14. 14
    The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group

    The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group حسب Mirko Koziolek, Stefano Alcaro, Patrick Augustijns, Abdul W. Basit, Michael Grimm, Bart Hens, Caroline L. Hoad, Philipp Jedamzik, Christine M. Madla, Marc Maliepaard, Luca Marciani, Annalisa Maruca, Neil Parrott, Petr Pávek, Christopher J. H. Porter, Christos Reppas, Diana A. van Riet‐Nales, Jari Rubbens, Marina Statelova, Natalie L. Trevaskis, Kateřina Valentová, Maria Vertzoni, Dubravka Vitali Čepo, Maura Corsetti

    منشور في 2019
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  15. 15
    Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

    Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network حسب Zahari Vinarov, Bertil Abrahamsson, Per Artursson, Hannah Batchelor, Philippe Berben, Andreas Bernkop‐Schnürch, James Butler, Jens Ceulemans, Nigel Davies, Didier Dupont, Gøril Eide Flaten, Nikoletta Fotaki, Brendan T. Griffin, Vincent Jannin, Janneke Keemink, Filippos Kesisoglou, Mirko Koziolek, Martin Kuentz, Alan R. Mackie, Antonio J. Meléndez‐Martínez, Mark McAllister, Anette Müllertz, Caitríona M. O’Driscoll, Neil Parrott, Jadwiga Paszkowska, Petr Pávek, Christopher J. H. Porter, Christos Reppas, Cordula Stillhart, Kiyohiko Sugano, Elena Toader, Kateřina Valentová, Maria Vertzoni, Saskia N. de Wildt, Clive Wilson, Patrick Augustijns

    منشور في 2021
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