Результати пошуку - Peter R. Strack

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  1. 1
    The SCFbeta -TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta -catenin and stimulates Ikappa Balpha ubiquitination in vitro

    The SCFbeta -TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta -catenin and stimulates Ikappa Balpha ubiquitina... за авторством Jeffrey Winston, Peter R. Strack, Peggy Beer‐Romero, Chia‐Yu Chu, Stephen J. Elledge, J. Wade Harper

    Опубліковано 1999
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  2. 2
    Oxygen Concentration Determines the Biological Effects of NOTCH-1 Signaling in Adenocarcinoma of the Lung

    Oxygen Concentration Determines the Biological Effects of NOTCH-1 Signaling in Adenocarcinoma of the Lung за авторством Yuanbin Chen, Melissa A. De Marco, Irene Graziani, Adi F. Gazdar, Peter R. Strack, Lucio Miele, Maurizio Bocchetta

    Опубліковано 2007
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  3. 3
    Inhibition of Notch Signaling Blocks Growth of Glioblastoma Cell Lines and Tumor Neurospheres

    Inhibition of Notch Signaling Blocks Growth of Glioblastoma Cell Lines and Tumor Neurospheres за авторством Y-H. Chen, Santosh Kesari, Cliona M. Rooney, Peter R. Strack, Y-H. Chen, Huangxuan Shen, Lizi Wu, J D Griffin

    Опубліковано 2010
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  4. 4
    Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models

    Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models за авторством Chaoxin Hu, Tikva Dadon, Venugopal Chenna, Shinichi Yabuuchi, Rajat Bannerji, Robert Booher, Peter R. Strack, Nilofer S. Azad, Barry D. Nelkin, Anirban Maitra

    Опубліковано 2015
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  5. 5
    Opposite Effects of Notch-1 and Notch-2 on Mesothelioma Cell Survival under Hypoxia Are Exerted through the Akt Pathway

    Opposite Effects of Notch-1 and Notch-2 on Mesothelioma Cell Survival under Hypoxia Are Exerted through the Akt Pathway за авторством Irene Graziani, Sandra Eliasz, Melissa A. De Marco, Yuanbin Chen, Harvey I. Pass, Richard M. De May, Peter R. Strack, Lucio Miele, Maurizio Bocchetta

    Опубліковано 2008
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  6. 6
    Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2.

    Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2. за авторством Peter R. Strack, Michelle West Frey, Carmelo J. Rizzo, Beverly C. Cordova, Henry J. George, Robin Meade, S. P. HO, John M. Corman, R.J. Tritch, Bruce D. Korant

    Опубліковано 1996
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  7. 7
    Differentiation of Hdm2-mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors

    Differentiation of Hdm2-mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors за авторством Zhihong Lai, Tao Yang, Young B. Kim, Thais M. Sielecki, Melody Diamond, Peter R. Strack, Mark Rolfe, Maureen Caligiuri, Pamela A. Benfield, Kurt R. Auger, Robert A. Copeland

    Опубліковано 2002
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  8. 8
    Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

    Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia за авторством Takaomi Sanda, Xiaoyu Li, Alejandro Gutiérrez, Yebin Ahn, Donna Neuberg, Jennifer O’Neil, Peter R. Strack, Christopher Winter, Stuart S. Winter, Richard A. Larson, Harald von Boehmer, A. Thomas Look

    Опубліковано 2009
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  9. 9
    <i>FBW7</i> mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

    <i>FBW7</i> mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors за авторством Jennifer O’Neil, Jonathan Grim, Peter R. Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James C.H. Hardwick, Markus Welcker, Jules P.P. Meijerink, Rob Pieters, Giulio Draetta, Rosalie C. Sears, Bruce E. Clurman, A. Thomas Look

    Опубліковано 2007
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  10. 10
    Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells

    Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells за авторством Sudhir Rao, Jennifer O’Neil, Cole D. Liberator, James S. Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E. Kohl, Victoria M. Richon, Lex H.T. Van der Ploeg, Pamela M. Carroll, Giulio Draetta, A. Thomas Look, Peter R. Strack, Christopher Winter

    Опубліковано 2009
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  11. 11
    Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells

    Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells за авторством Jieun Yun, Antonio Pannuti, Ignacio Espinoza, He Zhu, Chindo Hicks, Xulong Zhu, M. W. Caskey, Paola Rizzo, Gwendolyn D'Souza, Kandis V. Backus, Mitchell F. Denning, John S. Coon, Mu Sun, Emery H. Bresnick, Clodia Osipo, Jing Wu, Peter R. Strack, Debra A. Tonetti, Lucio Miele

    Опубліковано 2013
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  12. 12
    Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model

    Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model за авторством Clay L. Efferson, Christopher T. Winkelmann, Christopher Ware, Timothy M. Sullivan, Saverio Giampaoli, Jennifer Tammam, Shailendra B. Patel, Giuseppe Mesiti, John F. Reilly, Raymond E. Gibson, Carolyn A. Buser, Timothy J. Yeatman, Domenico Coppola, Christopher Winter, Edwin Clark, Giulio Draetta, Peter R. Strack, Pradip K. Majumder

    Опубліковано 2010
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  13. 13
    Evaluating TBK1 as a Therapeutic Target in Cancers with Activated IRF3

    Evaluating TBK1 as a Therapeutic Target in Cancers with Activated IRF3 за авторством Asli Muvaffak, Qi Pan, Haiyan Yan, Rafael Fernández, Jongwon Lim, Brian Dolinski, Thi Thinh Nguyen, Peter R. Strack, Stephen Wu, Rossana Chung, Weiqun Zhang, Chris Hulton, Steven Ripley, Heather A. Hirsch, Kumiko Nagashima, Kwok‐Kin Wong, Pasi A. Jänne, Cynthia Seidel‐Dugan, Leigh Zawel, Paul T. Kirschmeier, Richard E. Middleton, Erick J. Morris, Yan Wang

    Опубліковано 2014
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  14. 14
    Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia

    Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia за авторством Jennifer Tammam, C. Ware, Clay L. Efferson, Jennifer O’Neil, Sudhir Rao, Xianlu Qu, Julie Gorenstein, Minilik Angagaw, H Kim, Candia M. Kenific, Kaiko Kunii, KJ Leach, George N. Nikov, Junlong Zhao, Xudong Dai, James C.H. Hardwick, Martin Scott, Christopher Winter, Linda J. Bristow, Cem Elbi, John F. Reilly, Thomas Look, Giulio Draetta, LHT Van der Ploeg, NE Kohl, Peter R. Strack, PK Majumder

    Опубліковано 2009
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  15. 15
    MCL1 and BCL-xL Levels in Solid Tumors Are Predictive of Dinaciclib-Induced Apoptosis

    MCL1 and BCL-xL Levels in Solid Tumors Are Predictive of Dinaciclib-Induced Apoptosis за авторством Robert N. Booher, Harold Hatch, Brian Dolinski, Thi Phuong Nguyen, Lauren Harmonay, Ali-Samer Al-Assaad, Mark Ayers, Michael Nebozhyn, Andrey Loboda, Heather A. Hirsch, Theresa Zhang, Bin Shi, C. Merkel, Minilik Angagaw, Yaolin Wang, Brian J. Long, Xianlu Q. Lennon, Nathan R. Miselis, Vincenzo Pucci, James W. Monahan, Junghoon Lee, Anna Kondic, Eun Kyung Im, David Mauro, Rebecca Blanchard, Gary Gilliland, Stephen E. Fawell, Leigh Zawel, Alwin G. Schuller, Peter R. Strack

    Опубліковано 2014
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