検索結果 - Peter R. Strack

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  1. 1
    The SCFbeta -TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta -catenin and stimulates Ikappa Balpha ubiquitination in vitro

    The SCFbeta -TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta -catenin and stimulates Ikappa Balpha ubiquitina... 著者: Jeffrey Winston, Peter R. Strack, Peggy Beer‐Romero, Chia‐Yu Chu, Stephen J. Elledge, J. Wade Harper

    出版事項 1999
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  2. 2
    Oxygen Concentration Determines the Biological Effects of NOTCH-1 Signaling in Adenocarcinoma of the Lung

    Oxygen Concentration Determines the Biological Effects of NOTCH-1 Signaling in Adenocarcinoma of the Lung 著者: Yuanbin Chen, Melissa A. De Marco, Irene Graziani, Adi F. Gazdar, Peter R. Strack, Lucio Miele, Maurizio Bocchetta

    出版事項 2007
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  3. 3
    Inhibition of Notch Signaling Blocks Growth of Glioblastoma Cell Lines and Tumor Neurospheres

    Inhibition of Notch Signaling Blocks Growth of Glioblastoma Cell Lines and Tumor Neurospheres 著者: Y-H. Chen, Santosh Kesari, Cliona M. Rooney, Peter R. Strack, Y-H. Chen, Huangxuan Shen, Lizi Wu, J D Griffin

    出版事項 2010
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    Artigo
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  4. 4
    Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models

    Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models 著者: Chaoxin Hu, Tikva Dadon, Venugopal Chenna, Shinichi Yabuuchi, Rajat Bannerji, Robert Booher, Peter R. Strack, Nilofer S. Azad, Barry D. Nelkin, Anirban Maitra

    出版事項 2015
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    Artigo
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  5. 5
    Opposite Effects of Notch-1 and Notch-2 on Mesothelioma Cell Survival under Hypoxia Are Exerted through the Akt Pathway

    Opposite Effects of Notch-1 and Notch-2 on Mesothelioma Cell Survival under Hypoxia Are Exerted through the Akt Pathway 著者: Irene Graziani, Sandra Eliasz, Melissa A. De Marco, Yuanbin Chen, Harvey I. Pass, Richard M. De May, Peter R. Strack, Lucio Miele, Maurizio Bocchetta

    出版事項 2008
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    Artigo
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  6. 6
    Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2.

    Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2. 著者: Peter R. Strack, Michelle West Frey, Carmelo J. Rizzo, Beverly C. Cordova, Henry J. George, Robin Meade, S. P. HO, John M. Corman, R.J. Tritch, Bruce D. Korant

    出版事項 1996
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  7. 7
    Differentiation of Hdm2-mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors

    Differentiation of Hdm2-mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors 著者: Zhihong Lai, Tao Yang, Young B. Kim, Thais M. Sielecki, Melody Diamond, Peter R. Strack, Mark Rolfe, Maureen Caligiuri, Pamela A. Benfield, Kurt R. Auger, Robert A. Copeland

    出版事項 2002
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  8. 8
    Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

    Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia 著者: Takaomi Sanda, Xiaoyu Li, Alejandro Gutiérrez, Yebin Ahn, Donna Neuberg, Jennifer O’Neil, Peter R. Strack, Christopher Winter, Stuart S. Winter, Richard A. Larson, Harald von Boehmer, A. Thomas Look

    出版事項 2009
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    Artigo
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  9. 9
    <i>FBW7</i> mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

    <i>FBW7</i> mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors 著者: Jennifer O’Neil, Jonathan Grim, Peter R. Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James C.H. Hardwick, Markus Welcker, Jules P.P. Meijerink, Rob Pieters, Giulio Draetta, Rosalie C. Sears, Bruce E. Clurman, A. Thomas Look

    出版事項 2007
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    Artigo
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  10. 10
    Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells

    Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells 著者: Sudhir Rao, Jennifer O’Neil, Cole D. Liberator, James S. Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E. Kohl, Victoria M. Richon, Lex H.T. Van der Ploeg, Pamela M. Carroll, Giulio Draetta, A. Thomas Look, Peter R. Strack, Christopher Winter

    出版事項 2009
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    Artigo
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  11. 11
    Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells

    Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells 著者: Jieun Yun, Antonio Pannuti, Ignacio Espinoza, He Zhu, Chindo Hicks, Xulong Zhu, M. W. Caskey, Paola Rizzo, Gwendolyn D'Souza, Kandis V. Backus, Mitchell F. Denning, John S. Coon, Mu Sun, Emery H. Bresnick, Clodia Osipo, Jing Wu, Peter R. Strack, Debra A. Tonetti, Lucio Miele

    出版事項 2013
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    Artigo
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  12. 12
    Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model

    Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model 著者: Clay L. Efferson, Christopher T. Winkelmann, Christopher Ware, Timothy M. Sullivan, Saverio Giampaoli, Jennifer Tammam, Shailendra B. Patel, Giuseppe Mesiti, John F. Reilly, Raymond E. Gibson, Carolyn A. Buser, Timothy J. Yeatman, Domenico Coppola, Christopher Winter, Edwin Clark, Giulio Draetta, Peter R. Strack, Pradip K. Majumder

    出版事項 2010
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    Artigo
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  13. 13
    Evaluating TBK1 as a Therapeutic Target in Cancers with Activated IRF3

    Evaluating TBK1 as a Therapeutic Target in Cancers with Activated IRF3 著者: Asli Muvaffak, Qi Pan, Haiyan Yan, Rafael Fernández, Jongwon Lim, Brian Dolinski, Thi Thinh Nguyen, Peter R. Strack, Stephen Wu, Rossana Chung, Weiqun Zhang, Chris Hulton, Steven Ripley, Heather A. Hirsch, Kumiko Nagashima, Kwok‐Kin Wong, Pasi A. Jänne, Cynthia Seidel‐Dugan, Leigh Zawel, Paul T. Kirschmeier, Richard E. Middleton, Erick J. Morris, Yan Wang

    出版事項 2014
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    Artigo
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  14. 14
    Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia

    Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia 著者: Jennifer Tammam, C. Ware, Clay L. Efferson, Jennifer O’Neil, Sudhir Rao, Xianlu Qu, Julie Gorenstein, Minilik Angagaw, H Kim, Candia M. Kenific, Kaiko Kunii, KJ Leach, George N. Nikov, Junlong Zhao, Xudong Dai, James C.H. Hardwick, Martin Scott, Christopher Winter, Linda J. Bristow, Cem Elbi, John F. Reilly, Thomas Look, Giulio Draetta, LHT Van der Ploeg, NE Kohl, Peter R. Strack, PK Majumder

    出版事項 2009
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    Artigo
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  15. 15
    MCL1 and BCL-xL Levels in Solid Tumors Are Predictive of Dinaciclib-Induced Apoptosis

    MCL1 and BCL-xL Levels in Solid Tumors Are Predictive of Dinaciclib-Induced Apoptosis 著者: Robert N. Booher, Harold Hatch, Brian Dolinski, Thi Phuong Nguyen, Lauren Harmonay, Ali-Samer Al-Assaad, Mark Ayers, Michael Nebozhyn, Andrey Loboda, Heather A. Hirsch, Theresa Zhang, Bin Shi, C. Merkel, Minilik Angagaw, Yaolin Wang, Brian J. Long, Xianlu Q. Lennon, Nathan R. Miselis, Vincenzo Pucci, James W. Monahan, Junghoon Lee, Anna Kondic, Eun Kyung Im, David Mauro, Rebecca Blanchard, Gary Gilliland, Stephen E. Fawell, Leigh Zawel, Alwin G. Schuller, Peter R. Strack

    出版事項 2014
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