Torthaí cuardaigh - Peter R. Strack
- 1 - 15 toradh as 15 á dtaispeáint
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1
The SCFbeta -TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta -catenin and stimulates Ikappa Balpha ubiquitina... de réir Jeffrey Winston, Peter R. Strack, Peggy Beer‐Romero, Chia‐Yu Chu, Stephen J. Elledge, J. Wade Harper
Foilsithe / Cruthaithe 1999Artigo -
2
Oxygen Concentration Determines the Biological Effects of NOTCH-1 Signaling in Adenocarcinoma of the Lung de réir Yuanbin Chen, Melissa A. De Marco, Irene Graziani, Adi F. Gazdar, Peter R. Strack, Lucio Miele, Maurizio Bocchetta
Foilsithe / Cruthaithe 2007Artigo -
3
Inhibition of Notch Signaling Blocks Growth of Glioblastoma Cell Lines and Tumor Neurospheres de réir Y-H. Chen, Santosh Kesari, Cliona M. Rooney, Peter R. Strack, Y-H. Chen, Huangxuan Shen, Lizi Wu, J D Griffin
Foilsithe / Cruthaithe 2010Artigo -
4
Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models de réir Chaoxin Hu, Tikva Dadon, Venugopal Chenna, Shinichi Yabuuchi, Rajat Bannerji, Robert Booher, Peter R. Strack, Nilofer S. Azad, Barry D. Nelkin, Anirban Maitra
Foilsithe / Cruthaithe 2015Artigo -
5
Opposite Effects of Notch-1 and Notch-2 on Mesothelioma Cell Survival under Hypoxia Are Exerted through the Akt Pathway de réir Irene Graziani, Sandra Eliasz, Melissa A. De Marco, Yuanbin Chen, Harvey I. Pass, Richard M. De May, Peter R. Strack, Lucio Miele, Maurizio Bocchetta
Foilsithe / Cruthaithe 2008Artigo -
6
Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2. de réir Peter R. Strack, Michelle West Frey, Carmelo J. Rizzo, Beverly C. Cordova, Henry J. George, Robin Meade, S. P. HO, John M. Corman, R.J. Tritch, Bruce D. Korant
Foilsithe / Cruthaithe 1996Artigo -
7
Differentiation of Hdm2-mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors de réir Zhihong Lai, Tao Yang, Young B. Kim, Thais M. Sielecki, Melody Diamond, Peter R. Strack, Mark Rolfe, Maureen Caligiuri, Pamela A. Benfield, Kurt R. Auger, Robert A. Copeland
Foilsithe / Cruthaithe 2002Artigo -
8
Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia de réir Takaomi Sanda, Xiaoyu Li, Alejandro Gutiérrez, Yebin Ahn, Donna Neuberg, Jennifer O’Neil, Peter R. Strack, Christopher Winter, Stuart S. Winter, Richard A. Larson, Harald von Boehmer, A. Thomas Look
Foilsithe / Cruthaithe 2009Artigo -
9
<i>FBW7</i> mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors de réir Jennifer O’Neil, Jonathan Grim, Peter R. Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James C.H. Hardwick, Markus Welcker, Jules P.P. Meijerink, Rob Pieters, Giulio Draetta, Rosalie C. Sears, Bruce E. Clurman, A. Thomas Look
Foilsithe / Cruthaithe 2007Artigo -
10
Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells de réir Sudhir Rao, Jennifer O’Neil, Cole D. Liberator, James S. Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E. Kohl, Victoria M. Richon, Lex H.T. Van der Ploeg, Pamela M. Carroll, Giulio Draetta, A. Thomas Look, Peter R. Strack, Christopher Winter
Foilsithe / Cruthaithe 2009Artigo -
11
Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells de réir Jieun Yun, Antonio Pannuti, Ignacio Espinoza, He Zhu, Chindo Hicks, Xulong Zhu, M. W. Caskey, Paola Rizzo, Gwendolyn D'Souza, Kandis V. Backus, Mitchell F. Denning, John S. Coon, Mu Sun, Emery H. Bresnick, Clodia Osipo, Jing Wu, Peter R. Strack, Debra A. Tonetti, Lucio Miele
Foilsithe / Cruthaithe 2013Artigo -
12
Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model de réir Clay L. Efferson, Christopher T. Winkelmann, Christopher Ware, Timothy M. Sullivan, Saverio Giampaoli, Jennifer Tammam, Shailendra B. Patel, Giuseppe Mesiti, John F. Reilly, Raymond E. Gibson, Carolyn A. Buser, Timothy J. Yeatman, Domenico Coppola, Christopher Winter, Edwin Clark, Giulio Draetta, Peter R. Strack, Pradip K. Majumder
Foilsithe / Cruthaithe 2010Artigo -
13
Evaluating TBK1 as a Therapeutic Target in Cancers with Activated IRF3 de réir Asli Muvaffak, Qi Pan, Haiyan Yan, Rafael Fernández, Jongwon Lim, Brian Dolinski, Thi Thinh Nguyen, Peter R. Strack, Stephen Wu, Rossana Chung, Weiqun Zhang, Chris Hulton, Steven Ripley, Heather A. Hirsch, Kumiko Nagashima, Kwok‐Kin Wong, Pasi A. Jänne, Cynthia Seidel‐Dugan, Leigh Zawel, Paul T. Kirschmeier, Richard E. Middleton, Erick J. Morris, Yan Wang
Foilsithe / Cruthaithe 2014Artigo -
14
Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia de réir Jennifer Tammam, C. Ware, Clay L. Efferson, Jennifer O’Neil, Sudhir Rao, Xianlu Qu, Julie Gorenstein, Minilik Angagaw, H Kim, Candia M. Kenific, Kaiko Kunii, KJ Leach, George N. Nikov, Junlong Zhao, Xudong Dai, James C.H. Hardwick, Martin Scott, Christopher Winter, Linda J. Bristow, Cem Elbi, John F. Reilly, Thomas Look, Giulio Draetta, LHT Van der Ploeg, NE Kohl, Peter R. Strack, PK Majumder
Foilsithe / Cruthaithe 2009Artigo -
15
MCL1 and BCL-xL Levels in Solid Tumors Are Predictive of Dinaciclib-Induced Apoptosis de réir Robert N. Booher, Harold Hatch, Brian Dolinski, Thi Phuong Nguyen, Lauren Harmonay, Ali-Samer Al-Assaad, Mark Ayers, Michael Nebozhyn, Andrey Loboda, Heather A. Hirsch, Theresa Zhang, Bin Shi, C. Merkel, Minilik Angagaw, Yaolin Wang, Brian J. Long, Xianlu Q. Lennon, Nathan R. Miselis, Vincenzo Pucci, James W. Monahan, Junghoon Lee, Anna Kondic, Eun Kyung Im, David Mauro, Rebecca Blanchard, Gary Gilliland, Stephen E. Fawell, Leigh Zawel, Alwin G. Schuller, Peter R. Strack
Foilsithe / Cruthaithe 2014Artigo
Uirlisí cuardaigh:
Ábhair a bhaineann le hábhar
Biology
Cell biology
Cancer research
Signal transduction
Gene
Genetics
Notch signaling pathway
Biochemistry
Cancer
Medicine
Internal medicine
Cell culture
Protein kinase B
Apoptosis
Cell growth
Chemistry
Gene knockdown
In vitro
Molecular biology
PI3K/AKT/mTOR pathway
Ubiquitin
Ubiquitin ligase
Biotechnology
Breast cancer
Cell cycle
Colorectal cancer
Downregulation and upregulation
Enzyme
Hes3 signaling axis
In vivo