檢索結果 - Peter Mullen
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Systems Biology Reveals New Strategies for Personalizing Cancer Medicine and Confirms the Role of PTEN in Resistance to Trastuzumab 由 Dana Faratian, Alexey Goltsov, Galina Lebedeva, Anatoly Sorokin, Stuart Moodie, Peter Mullen, Charlene Kay, In Hwa Um, Simon P. Langdon, Igor Goryanin, David J. Harrison
出版 2009Artigo -
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Immediate Utility of Two Approved Agents to Target Both the Metabolic Mevalonate Pathway and Its Restorative Feedback Loop 由 Aleksandra A. Pandyra, Peter Mullen, Manpreet Kalkat, Rosemary Yu, Janice T. Pong, Zhihua Li, Suzanne Trudel, Karl S. Lang, Mark D. Minden, Aaron D. Schimmer, Linda Z. Penn
出版 2014Artigo -
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Trastuzumab and Pertuzumab Produce Changes in Morphology and Estrogen Receptor Signaling in Ovarian Cancer Xenografts Revealing New Treatment Strategies 由 Dana Faratian, Annelien J.M. Zweemer, Yoko Nagumo, Andrew H. Sims, Morwenna Muir, Michael Dodds, Peter Mullen, Inhwa Um, Charlene Kay, Max Hasmann, David J. Harrison, Simon P. Langdon
出版 2011Artigo -
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An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer 由 Joseph Longo, Peter Mullen, Rosemary Yu, Jenna E. van Leeuwen, Mehdi Masoomian, Dixon Woon, Yuzhuo Wang, Eric X. Chen, Robert J. Hamilton, Joan Sweet, Theodorus van der Kwast, Neil Fleshner, Linda Z. Penn
出版 2019Artigo -
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Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death 由 Aleksandra A. Pandyra, Peter Mullen, Carolyn A. Goard, Elke Ericson, Piyush Sharma, Manpreet Kalkat, Rosemary Yu, Janice T. Pong, Kevin R. Brown, Traver Hart, Marinella Gebbia, Karl S. Lang, Guri Giaever, Corey Nislow, Jason Moffat, Linda Z. Penn
出版 2015Artigo -
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A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer 由 Joseph Longo, Robert J. Hamilton, Mehdi Masoomian, Najia Khurram, Emily Branchard, Peter Mullen, Mohamad Elbaz, Karen Hersey, Dianne Chadwick, Sangeet Ghai, David W. Andrews, Eric X. Chen, Theodorus van der Kwast, Neil Fleshner, Linda Z. Penn
出版 2020Artigo -
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SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition 由 Peter Mullen, Gustavo Garcia, Arunima Purkayastha, Nedas Matulionis, E. Schmid, Milica Momcilovic, Chandani Sen, Justin Langerman, Arunachalam Ramaiah, David B. Shackelford, Robert Damoiseaux, Samuel W. French, Kathrin Plath, Brigitte N. Gomperts, Vaithilingaraja Arumugaswami, Heather R. Christofk
出版 2021Artigo -
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Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells 由 James Meehan, Carol Ward, Arran Turnbull, Jimi Wills, Andrew J. Finch, Edward J. Jarman, Chrysi Xintaropoulou, Carlos Martínez-Pérez, Mark Gray, Matthew Pearson, Peter Mullen, Claudiu T. Supuran, Fabrizio Carta, David J. Harrison, Ian Kunkler, Simon P. Langdon
出版 2017Artigo -
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Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of<i>in vitro</i>breast cancer models 由 Carol Ward, James Meehan, Peter Mullen, Claudiu T. Supuran, J. Michael Dixon, Jeremy Thomas, Jean‐Yves Winum, Philippe Lambin, Ludwig J. Dubois, Nanda-Kumar Pavathaneni, Edward J. Jarman, Lorna Renshaw, In Hwa Um, Charlene Kay, David J. Harrison, Ian Kunkler, Simon P. Langdon
出版 2015Artigo -
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Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization 由 William J. Sullivan, Peter Mullen, E. Schmid, Aimee Flores, Milica Momcilovic, Mark S. Sharpley, David Jelínek, Andrew E. Whiteley, Matthew B. Maxwell, Blake R. Wilde, Utpal Banerjee, Hilary A. Coller, David B. Shackelford, Daniel Braas, Donald E. Ayer, Thomas Q. de Aguiar Vallim, William E. Lowry, Heather R. Christofk
出版 2018Artigo -
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Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells 由 Falko Hochgräfe, Luxi Zhang, Sandra O’Toole, Brigid C. Browne, Mark Pinese, Ana Porta Cubas, Gillian M. Lehrbach, David R. Croucher, Danny Rickwood, Alice Boulghourjian, Robert F. Shearer, Radhika Nair, Alexander Swarbrick, Dana Faratian, Peter Mullen, David J. Harrison, Andrew V. Biankin, Robert L. Sutherland, Mark J. Raftery, Roger J. Daly
出版 2010Artigo -
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AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress 由 Shrivani Sriskanthadevan, Danny V. Jeyaraju, Timothy Chung, Swayam Prabha, Wei Xu, Marko Škrtić, Bozhena Jhas, Rose Hurren, Marcela Gronda, Xiaoming Wang, Yulia Jitkova, Mahadeo A. Sukhai, Feng-Hsu Lin, Neil MacLean, Rob C. Laister, Carolyn A. Goard, Peter Mullen, Stephanie Z. Xie, Linda Z. Penn, Ian M. Rogers, John E. Dick, Mark D. Minden, Aaron D. Schimmer
出版 2015Artigo
相關主題
Biology
Cancer
Cancer research
Medicine
Internal medicine
Biochemistry
Cell biology
Genetics
Signal transduction
Breast cancer
Enzyme
Gene
Mevalonate pathway
Statin
Pharmacology
Reductase
Biosynthesis
Chemistry
Fluvastatin
HMG-CoA reductase
Oncology
Simvastatin
Apoptosis
Biotechnology
Cancer cell
Cell culture
Computational biology
In vivo
Metabolism
Ovarian cancer