Výsledky vyhledávání - Peter Mullen

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  1. 1
    The interplay between cell signalling and the mevalonate pathway in cancer

    The interplay between cell signalling and the mevalonate pathway in cancer Autor Peter Mullen, Rosemary Yu, Joseph Longo, Michael C. Archer, Linda Z. Penn

    Vydáno 2016
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  2. 2
    Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer

    Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer Autor Carlos Martínez-Pérez, Carol Ward, Graeme Cook, Peter Mullen, Donald B. McPhail, David J. Harrison, Simon P. Langdon

    Vydáno 2014
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  3. 3
    Embedding a Panoramic Representation of Infrared Light in the Adult Rat Somatosensory Cortex through a Sensory Neuroprosthesis

    Embedding a Panoramic Representation of Infrared Light in the Adult Rat Somatosensory Cortex through a Sensory Neuroprosthesis Autor Konstantin Hartmann, Eric E. Thomson, Ivan Zea, Richy Yun, Peter Mullen, Jay Canarick, Albert Huh, Miguel A. L. Nicolelis

    Vydáno 2016
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  4. 4
    Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins

    Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins Autor Rosemary Yu, Joseph Longo, Jenna E. van Leeuwen, Peter Mullen, Wail Ba-Alawi, Benjamin Haibe‐Kains, Linda Z. Penn

    Vydáno 2017
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  5. 5
    Altered ErbB Receptor Signaling and Gene Expression in Cisplatin-Resistant Ovarian Cancer

    Altered ErbB Receptor Signaling and Gene Expression in Cisplatin-Resistant Ovarian Cancer Autor Kenneth G. MacLeod, Peter Mullen, Jane Michelle Sewell, Genevieve J. Rabiasz, S. S. Lawrie, Eric P. Miller, John F. Smyth, Simon P. Langdon

    Vydáno 2005
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  6. 6
    Systems Biology Reveals New Strategies for Personalizing Cancer Medicine and Confirms the Role of PTEN in Resistance to Trastuzumab

    Systems Biology Reveals New Strategies for Personalizing Cancer Medicine and Confirms the Role of PTEN in Resistance to Trastuzumab Autor Dana Faratian, Alexey Goltsov, Galina Lebedeva, Anatoly Sorokin, Stuart Moodie, Peter Mullen, Charlene Kay, In Hwa Um, Simon P. Langdon, Igor Goryanin, David J. Harrison

    Vydáno 2009
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  7. 7
    Immediate Utility of Two Approved Agents to Target Both the Metabolic Mevalonate Pathway and Its Restorative Feedback Loop

    Immediate Utility of Two Approved Agents to Target Both the Metabolic Mevalonate Pathway and Its Restorative Feedback Loop Autor Aleksandra A. Pandyra, Peter Mullen, Manpreet Kalkat, Rosemary Yu, Janice T. Pong, Zhihua Li, Suzanne Trudel, Karl S. Lang, Mark D. Minden, Aaron D. Schimmer, Linda Z. Penn

    Vydáno 2014
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  8. 8
    Trastuzumab and Pertuzumab Produce Changes in Morphology and Estrogen Receptor Signaling in Ovarian Cancer Xenografts Revealing New Treatment Strategies

    Trastuzumab and Pertuzumab Produce Changes in Morphology and Estrogen Receptor Signaling in Ovarian Cancer Xenografts Revealing New Treatment Strategies Autor Dana Faratian, Annelien J.M. Zweemer, Yoko Nagumo, Andrew H. Sims, Morwenna Muir, Michael Dodds, Peter Mullen, Inhwa Um, Charlene Kay, Max Hasmann, David J. Harrison, Simon P. Langdon

    Vydáno 2011
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  9. 9
    An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer

    An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer Autor Joseph Longo, Peter Mullen, Rosemary Yu, Jenna E. van Leeuwen, Mehdi Masoomian, Dixon Woon, Yuzhuo Wang, Eric X. Chen, Robert J. Hamilton, Joan Sweet, Theodorus van der Kwast, Neil Fleshner, Linda Z. Penn

    Vydáno 2019
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  10. 10
    Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death

    Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death Autor Aleksandra A. Pandyra, Peter Mullen, Carolyn A. Goard, Elke Ericson, Piyush Sharma, Manpreet Kalkat, Rosemary Yu, Janice T. Pong, Kevin R. Brown, Traver Hart, Marinella Gebbia, Karl S. Lang, Guri Giaever, Corey Nislow, Jason Moffat, Linda Z. Penn

    Vydáno 2015
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  11. 11
    A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer

    A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer Autor Joseph Longo, Robert J. Hamilton, Mehdi Masoomian, Najia Khurram, Emily Branchard, Peter Mullen, Mohamad Elbaz, Karen Hersey, Dianne Chadwick, Sangeet Ghai, David W. Andrews, Eric X. Chen, Theodorus van der Kwast, Neil Fleshner, Linda Z. Penn

    Vydáno 2020
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  12. 12
    SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition

    SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition Autor Peter Mullen, Gustavo Garcia, Arunima Purkayastha, Nedas Matulionis, E. Schmid, Milica Momcilovic, Chandani Sen, Justin Langerman, Arunachalam Ramaiah, David B. Shackelford, Robert Damoiseaux, Samuel W. French, Kathrin Plath, Brigitte N. Gomperts, Vaithilingaraja Arumugaswami, Heather R. Christofk

    Vydáno 2021
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  13. 13
    Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

    Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells Autor James Meehan, Carol Ward, Arran Turnbull, Jimi Wills, Andrew J. Finch, Edward J. Jarman, Chrysi Xintaropoulou, Carlos Martínez-Pérez, Mark Gray, Matthew Pearson, Peter Mullen, Claudiu T. Supuran, Fabrizio Carta, David J. Harrison, Ian Kunkler, Simon P. Langdon

    Vydáno 2017
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  14. 14
    Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of<i>in vitro</i>breast cancer models

    Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of<i>in vitro</i>breast cancer models Autor Carol Ward, James Meehan, Peter Mullen, Claudiu T. Supuran, J. Michael Dixon, Jeremy Thomas, Jean‐Yves Winum, Philippe Lambin, Ludwig J. Dubois, Nanda-Kumar Pavathaneni, Edward J. Jarman, Lorna Renshaw, In Hwa Um, Charlene Kay, David J. Harrison, Ian Kunkler, Simon P. Langdon

    Vydáno 2015
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  15. 15
    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization Autor William J. Sullivan, Peter Mullen, E. Schmid, Aimee Flores, Milica Momcilovic, Mark S. Sharpley, David Jelínek, Andrew E. Whiteley, Matthew B. Maxwell, Blake R. Wilde, Utpal Banerjee, Hilary A. Coller, David B. Shackelford, Daniel Braas, Donald E. Ayer, Thomas Q. de Aguiar Vallim, William E. Lowry, Heather R. Christofk

    Vydáno 2018
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  16. 16
    Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells

    Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells Autor Falko Hochgräfe, Luxi Zhang, Sandra O’Toole, Brigid C. Browne, Mark Pinese, Ana Porta Cubas, Gillian M. Lehrbach, David R. Croucher, Danny Rickwood, Alice Boulghourjian, Robert F. Shearer, Radhika Nair, Alexander Swarbrick, Dana Faratian, Peter Mullen, David J. Harrison, Andrew V. Biankin, Robert L. Sutherland, Mark J. Raftery, Roger J. Daly

    Vydáno 2010
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  17. 17
    AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

    AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress Autor Shrivani Sriskanthadevan, Danny V. Jeyaraju, Timothy Chung, Swayam Prabha, Wei Xu, Marko Škrtić, Bozhena Jhas, Rose Hurren, Marcela Gronda, Xiaoming Wang, Yulia Jitkova, Mahadeo A. Sukhai, Feng-Hsu Lin, Neil MacLean, Rob C. Laister, Carolyn A. Goard, Peter Mullen, Stephanie Z. Xie, Linda Z. Penn, Ian M. Rogers, John E. Dick, Mark D. Minden, Aaron D. Schimmer

    Vydáno 2015
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