检索结果 - Peter J. Choi
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Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles 由 Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi, Daniel Conole, Adrian Blaser, Scott G. Franzblau, Christopher B. Cooper, Anna M. Upton, Manisha U. Lotlikar, William A. Denny, Brian D. Palmer
出版 2018Artigo -
2
Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline 由 Adrian Blaser, Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi, Daniel Conole, Scott G. Franzblau, Christopher B. Cooper, Anna M. Upton, Manisha U. Lotlikar, William A. Denny, Brian D. Palmer
出版 2019Artigo -
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3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel 由 Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi, Adrian Blaser, Daniel Conole, Scott G. Franzblau, Manisha U. Lotlikar, Christopher B. Cooper, Anna M. Upton, William A. Denny, Brian D. Palmer
出版 2019Artigo -
4
6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis 由 Amy S.T. Tong, Peter J. Choi, Adrian Blaser, Hamish S. Sutherland, Sophia K. Y. Tsang, Jérôme Guillemont, Magali Motte, Christopher B. Cooper, Koen Andries, Walter Van den Broeck, Scott G. Franzblau, Anna M. Upton, William A. Denny, Brian D. Palmer, Daniel Conole
出版 2017Artigo -
5
Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units 由 Peter J. Choi, Hamish S. Sutherland, Amy S.T. Tong, Adrian Blaser, Scott G. Franzblau, Christopher B. Cooper, Manisha U. Lotlikar, Anna M. Upton, Jérôme Guillemont, Magali Motte, Laurence Quéguiner, Koen Andries, Walter Van den Broeck, William A. Denny, Brian D. Palmer
出版 2017Artigo
相关主题
Bedaquiline
Biochemistry
Chemistry
In vitro
Lipophilicity
Medicine
Mycobacterium tuberculosis
Pathology
Pharmacology
Potassium channel
Stereochemistry
Tuberculosis
hERG
Biology
Drug
Combinatorial chemistry
Internal medicine
Potency
Biophysics
Biotechnology
In vivo
Lead compound
Organic chemistry
Bicyclic molecule
Bioavailability
Chemical synthesis
Efflux
IC50
Membrane
Naphthalene