Search Results - Peter J. Choi
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1
Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles by Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi, Daniel Conole, Adrian Blaser, Scott G. Franzblau, Christopher B. Cooper, Anna M. Upton, Manisha U. Lotlikar, William A. Denny, Brian D. Palmer
Published 2018Artigo -
2
Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline by Adrian Blaser, Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi, Daniel Conole, Scott G. Franzblau, Christopher B. Cooper, Anna M. Upton, Manisha U. Lotlikar, William A. Denny, Brian D. Palmer
Published 2019Artigo -
3
3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel by Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi, Adrian Blaser, Daniel Conole, Scott G. Franzblau, Manisha U. Lotlikar, Christopher B. Cooper, Anna M. Upton, William A. Denny, Brian D. Palmer
Published 2019Artigo -
4
6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis by Amy S.T. Tong, Peter J. Choi, Adrian Blaser, Hamish S. Sutherland, Sophia K. Y. Tsang, Jérôme Guillemont, Magali Motte, Christopher B. Cooper, Koen Andries, Walter Van den Broeck, Scott G. Franzblau, Anna M. Upton, William A. Denny, Brian D. Palmer, Daniel Conole
Published 2017Artigo -
5
Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units by Peter J. Choi, Hamish S. Sutherland, Amy S.T. Tong, Adrian Blaser, Scott G. Franzblau, Christopher B. Cooper, Manisha U. Lotlikar, Anna M. Upton, Jérôme Guillemont, Magali Motte, Laurence Quéguiner, Koen Andries, Walter Van den Broeck, William A. Denny, Brian D. Palmer
Published 2017Artigo
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Related Subjects
Bedaquiline
Biochemistry
Chemistry
In vitro
Lipophilicity
Medicine
Mycobacterium tuberculosis
Pathology
Pharmacology
Potassium channel
Stereochemistry
Tuberculosis
hERG
Biology
Drug
Combinatorial chemistry
Internal medicine
Potency
Biophysics
Biotechnology
In vivo
Lead compound
Organic chemistry
Bicyclic molecule
Bioavailability
Chemical synthesis
Efflux
IC50
Membrane
Naphthalene