Rezultati - Perry, Jason

The Epc-N domain: a predicted protein-protein interaction domain found in select chromatin associated proteins od Perry, Jason

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A Mutation in the Anticodon of a Single tRNA(ala) Is Sufficient to Confer Auxin Resistance in Arabidopsis od Perry, Jason, Dai, Xinhua, Zhao, Yunde

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Effects of transition metals on nitric oxide synthase catalysis od Perry, Jason M., Marletta, Michael A.

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Bioinformatic analyses implicate the collaborating meiotic crossover/chiasma proteins Zip2, Zip3, and Spo22/Zip4 in ubiquitin labeling od Perry, Jason, Kleckner, Nancy, Börner, G. Valentin

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1646. Combined Resistance Analyses From Phase 2b Studies of Presatovir Treatment in RSV-Infected Adults od Porter, Danielle, Guo, Ying, Perry, Jason, Gossage, David, Watkins, Timothy, Chien, Jason, Jordan, Robert

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Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resist... od Martin, Ross, Li, Jiani, Parvangada, Aiyappa, Perry, Jason, Cihlar, Tomas, Mo, Hongmei, Porter, Danielle, Svarovskaia, Evguenia

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An atomistic model of the coronavirus replication-transcription complex as a hexamer assembled around nsp15 od Perry, Jason K., Appleby, Todd C., Bilello, John P., Feng, Joy Y., Schmitz, Uli, Campbell, Elizabeth A.

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Assessment of Drug Resistance during Phase 2b Clinical Trials of Presatovir in Adults Naturally Infected with Respiratory Syncytial Virus od Porter, Danielle P., Guo, Ying, Perry, Jason, Gossage, David L., Watkins, Timothy R., Chien, Jason W., Jordan, Robert

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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency od Gordon, Calvin J., Tchesnokov, Egor P., Woolner, Emma, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action od Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocinkova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Correction: Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action od Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocincova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir od Gordon, Calvin J., Lee, Hery W., Tchesnokov, Egor P., Perry, Jason K., Feng, Joy Y., Bilello, John P., Porter, Danielle P., Götte, Matthias

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Optimized high-throughput screen for Hepatitis C virus translation inhibitors od Berry, Katherine E., Peng, Betty, Koditek, David, Beeman, Douglas, Pagratis, Nikos, Perry, Jason K., Parrish, Jay, Zhong, Weidong, Doudna, Jennifer A., Shih, I-hung

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Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex od Chen, James, Wang, Qi, Malone, Brandon, Llewellyn, Eliza, Pechersky, Yakov, Maruthi, Kashyap, Eng, Ed T., Perry, Jason K., Campbell, Elizabeth A., Shaw, David E., Darst, Seth A.

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Particle size and gastrointestinal absorption influence tiotropium pharmacokinetics: a pilot bioequivalence study of PUR0200 and Spiriva HandiHaler od Perry, Jason, Trautman, Brian, Takher‐Smith, Joe, Kramer, Steve, Kane, Katie, Silverman, Michael, Tan, Lisa, Haughie, Scott, Richter, Wolfram, Kirkov, Valentin, Arsova, Sacha, Ward, Jonathan, Hava, David L.

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In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance od Checkmahomed, Liva, Carbonneau, Julie, Du Pont, Venice, Riola, Nicholas C., Perry, Jason K., Li, Jiani, Paré, Bastien, Simpson, Shawn M., Smith, Martin A., Porter, Danielle P., Boivin, Guy

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Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors od Lansdon, Eric B., Liu, Qi, Leavitt, Stephanie A., Balakrishnan, Mini, Perry, Jason K., Lancaster-Moyer, Candra, Kutty, Nilima, Liu, Xiaohong, Squires, Neil H., Watkins, William J., Kirschberg, Thorsten A.

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Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors od Boyce, Sarah E., Tirunagari, Neeraj, Niedziela-Majka, Anita, Perry, Jason, Wong, Melanie, Kan, Elaine, Lagpacan, Leanna, Barauskas, Ona, Hung, Magdeleine, Fenaux, Martijn, Appleby, Todd, Watkins, William J., Schmitz, Uli, Sakowicz, Roman

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A New Natural Defense Against Airborne Pathogens od Edwards, David, Hickey, Anthony, Batycky, Richard, Griel, Lester, Lipp, Michael, Dehaan, Wes, Clarke, Robert, Hava, David, Perry, Jason, Laurenzi, Brendan, Curran, Aidan K., Beddingfield, Brandon J., Roy, Chad J., Devlin, Tom, Langer, Robert

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A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics od Hava, David L., Tan, Lisa, Johnson, Patrick, Curran, Aidan K., Perry, Jason, Kramer, Steve, Kane, Katie, Bedwell, Pauline, Layton, Gary, Swann, Clarie, Henderson, Dennis, Khan, Naimat, Connor, Lucy, McKenzie, Litza, Singh, Dave, Roach, James

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