Resultados de procura - Perry, Jason
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Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resist... por Martin, Ross, Li, Jiani, Parvangada, Aiyappa, Perry, Jason, Cihlar, Tomas, Mo, Hongmei, Porter, Danielle, Svarovskaia, Evguenia
Publicado 2021Text -
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Assessment of Drug Resistance during Phase 2b Clinical Trials of Presatovir in Adults Naturally Infected with Respiratory Syncytial Virus por Porter, Danielle P., Guo, Ying, Perry, Jason, Gossage, David L., Watkins, Timothy R., Chien, Jason W., Jordan, Robert
Publicado 2020Text -
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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency por Gordon, Calvin J., Tchesnokov, Egor P., Woolner, Emma, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias
Publicado 2020Text -
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Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action por Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocinkova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias
Publicado 2020Text -
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Correction: Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action por Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocincova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias
Publicado 2021Text -
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Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir por Gordon, Calvin J., Lee, Hery W., Tchesnokov, Egor P., Perry, Jason K., Feng, Joy Y., Bilello, John P., Porter, Danielle P., Götte, Matthias
Publicado 2021Text -
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Optimized high-throughput screen for Hepatitis C virus translation inhibitors por Berry, Katherine E., Peng, Betty, Koditek, David, Beeman, Douglas, Pagratis, Nikos, Perry, Jason K., Parrish, Jay, Zhong, Weidong, Doudna, Jennifer A., Shih, I-hung
Publicado 2011Text -
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Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex por Chen, James, Wang, Qi, Malone, Brandon, Llewellyn, Eliza, Pechersky, Yakov, Maruthi, Kashyap, Eng, Ed T., Perry, Jason K., Campbell, Elizabeth A., Shaw, David E., Darst, Seth A.
Publicado 2022Text -
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Particle size and gastrointestinal absorption influence tiotropium pharmacokinetics: a pilot bioequivalence study of PUR0200 and Spiriva HandiHaler por Perry, Jason, Trautman, Brian, Takher‐Smith, Joe, Kramer, Steve, Kane, Katie, Silverman, Michael, Tan, Lisa, Haughie, Scott, Richter, Wolfram, Kirkov, Valentin, Arsova, Sacha, Ward, Jonathan, Hava, David L.
Publicado 2019Text -
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In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance por Checkmahomed, Liva, Carbonneau, Julie, Du Pont, Venice, Riola, Nicholas C., Perry, Jason K., Li, Jiani, Paré, Bastien, Simpson, Shawn M., Smith, Martin A., Porter, Danielle P., Boivin, Guy
Publicado 2022Text -
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Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors por Lansdon, Eric B., Liu, Qi, Leavitt, Stephanie A., Balakrishnan, Mini, Perry, Jason K., Lancaster-Moyer, Candra, Kutty, Nilima, Liu, Xiaohong, Squires, Neil H., Watkins, William J., Kirschberg, Thorsten A.
Publicado 2011Text -
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Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors por Boyce, Sarah E., Tirunagari, Neeraj, Niedziela-Majka, Anita, Perry, Jason, Wong, Melanie, Kan, Elaine, Lagpacan, Leanna, Barauskas, Ona, Hung, Magdeleine, Fenaux, Martijn, Appleby, Todd, Watkins, William J., Schmitz, Uli, Sakowicz, Roman
Publicado 2014Text -
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A New Natural Defense Against Airborne Pathogens por Edwards, David, Hickey, Anthony, Batycky, Richard, Griel, Lester, Lipp, Michael, Dehaan, Wes, Clarke, Robert, Hava, David, Perry, Jason, Laurenzi, Brendan, Curran, Aidan K., Beddingfield, Brandon J., Roy, Chad J., Devlin, Tom, Langer, Robert
Publicado 2020Text -
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A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics por Hava, David L., Tan, Lisa, Johnson, Patrick, Curran, Aidan K., Perry, Jason, Kramer, Steve, Kane, Katie, Bedwell, Pauline, Layton, Gary, Swann, Clarie, Henderson, Dennis, Khan, Naimat, Connor, Lucy, McKenzie, Litza, Singh, Dave, Roach, James
Publicado 2020Text