Search Results - Perry, Jason
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Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resist... by Martin, Ross, Li, Jiani, Parvangada, Aiyappa, Perry, Jason, Cihlar, Tomas, Mo, Hongmei, Porter, Danielle, Svarovskaia, Evguenia
Published 2021Text -
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Assessment of Drug Resistance during Phase 2b Clinical Trials of Presatovir in Adults Naturally Infected with Respiratory Syncytial Virus by Porter, Danielle P., Guo, Ying, Perry, Jason, Gossage, David L., Watkins, Timothy R., Chien, Jason W., Jordan, Robert
Published 2020Text -
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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency by Gordon, Calvin J., Tchesnokov, Egor P., Woolner, Emma, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias
Published 2020Text -
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Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action by Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocinkova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias
Published 2020Text -
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Correction: Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action by Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocincova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias
Published 2021Text -
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Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir by Gordon, Calvin J., Lee, Hery W., Tchesnokov, Egor P., Perry, Jason K., Feng, Joy Y., Bilello, John P., Porter, Danielle P., Götte, Matthias
Published 2021Text -
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Optimized high-throughput screen for Hepatitis C virus translation inhibitors by Berry, Katherine E., Peng, Betty, Koditek, David, Beeman, Douglas, Pagratis, Nikos, Perry, Jason K., Parrish, Jay, Zhong, Weidong, Doudna, Jennifer A., Shih, I-hung
Published 2011Text -
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Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex by Chen, James, Wang, Qi, Malone, Brandon, Llewellyn, Eliza, Pechersky, Yakov, Maruthi, Kashyap, Eng, Ed T., Perry, Jason K., Campbell, Elizabeth A., Shaw, David E., Darst, Seth A.
Published 2022Text -
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Particle size and gastrointestinal absorption influence tiotropium pharmacokinetics: a pilot bioequivalence study of PUR0200 and Spiriva HandiHaler by Perry, Jason, Trautman, Brian, Takher‐Smith, Joe, Kramer, Steve, Kane, Katie, Silverman, Michael, Tan, Lisa, Haughie, Scott, Richter, Wolfram, Kirkov, Valentin, Arsova, Sacha, Ward, Jonathan, Hava, David L.
Published 2019Text -
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In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance by Checkmahomed, Liva, Carbonneau, Julie, Du Pont, Venice, Riola, Nicholas C., Perry, Jason K., Li, Jiani, Paré, Bastien, Simpson, Shawn M., Smith, Martin A., Porter, Danielle P., Boivin, Guy
Published 2022Text -
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Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors by Lansdon, Eric B., Liu, Qi, Leavitt, Stephanie A., Balakrishnan, Mini, Perry, Jason K., Lancaster-Moyer, Candra, Kutty, Nilima, Liu, Xiaohong, Squires, Neil H., Watkins, William J., Kirschberg, Thorsten A.
Published 2011Text -
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Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors by Boyce, Sarah E., Tirunagari, Neeraj, Niedziela-Majka, Anita, Perry, Jason, Wong, Melanie, Kan, Elaine, Lagpacan, Leanna, Barauskas, Ona, Hung, Magdeleine, Fenaux, Martijn, Appleby, Todd, Watkins, William J., Schmitz, Uli, Sakowicz, Roman
Published 2014Text -
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A New Natural Defense Against Airborne Pathogens by Edwards, David, Hickey, Anthony, Batycky, Richard, Griel, Lester, Lipp, Michael, Dehaan, Wes, Clarke, Robert, Hava, David, Perry, Jason, Laurenzi, Brendan, Curran, Aidan K., Beddingfield, Brandon J., Roy, Chad J., Devlin, Tom, Langer, Robert
Published 2020Text -
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A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics by Hava, David L., Tan, Lisa, Johnson, Patrick, Curran, Aidan K., Perry, Jason, Kramer, Steve, Kane, Katie, Bedwell, Pauline, Layton, Gary, Swann, Clarie, Henderson, Dennis, Khan, Naimat, Connor, Lucy, McKenzie, Litza, Singh, Dave, Roach, James
Published 2020Text